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An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review

Journal

POLYMER BULLETIN
Volume 80, Issue 1, Pages 241-262

Publisher

SPRINGER
DOI: 10.1007/s00289-022-04091-8

Keywords

Quercetin; Antioxidant; Anticancer; Antidiabetic; Antimicrobial; Anti-inflammatory

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Flavonoids, such as quercetin, are powerful natural antioxidants and cytotoxic compounds found in many fruits and vegetables. A recent review highlighted the various roles of quercetin in the medical field, including antioxidant, antimicrobial, antidiabetic, anticancerous, and anti-inflammatory effects. The review also discussed the use of quercetin complexes in drug delivery systems and therapeutic interventions.
Flavonoids are present naturally in many fruits and vegetables including onions, apples, tea, cabbage, cauliflower, berries and nuts which provide us with quercetin, a powerful natural antioxidant and cytotoxic compound. Due to antioxidant property, many nutraceuticals and cosmeceuticals products contain quercetin as a major ingredient nowadays. Current review enlightened sources and quercetin's role as an antioxidant, antimicrobial, antidiabetic, anticancerous and anti-inflammatory agent in medical field during last 5 to 6 years. Literature search was systematically done using scientific for the published articles of quercetin. A total of 345 articles were reviewed, and it was observed that more than 40% of articles were about quercetin's use as an antioxidant agent, more than 25% of studies were about its use as an anticancer agent, and articles on antimicrobial activity were more than 15%. 10% of the articles showed anti-inflamamatory effects of quercetin. Literature search also revealed that quercetin alone and its complexes with chitosan, metal ions and polymers possessed good antidiabetic properties. Thus, the review focuses on new therapeutic interventions and drug delivery system of quercetin in medical field for the benefit of mankind.

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