Fe3O4@THAM-SO3H: An Eco-Friendly Solid Acid Nanocatalyst for Synthesis of 2-Amino-3-Cyanopyridines and 2,4,6-Triarylpyridines under Mild Reaction Conditions

A green and efficient pathway for the synthesis of 2-amino-3-cyanopyridines and 2,4,6-triarylpyridines has been developed using Fe3O4@THAM-SO3H nanoparticles as a highly reusable nanocatalyst under mild reaction conditions. The use of environmentally friendly conditions, easy separation and reusability of the catalyst, low cost and simple methodology, good to excellent yields (70-90%), and short reaction times (15-40 min) are the advantages of this method.

Automated summary

A green and efficient method for synthesizing 2-amino-3-cyanopyridines and 2,4,6-triarylpyridines has been developed using Fe3O4@THAM-SO3H nanoparticles as a highly reusable nanocatalyst. The method offers environmentally friendly conditions, easy separation and reusability of the catalyst, low cost, simple methodology, and high yields (70-90%) with short reaction times (15-40 min).