Severe COVID-19 in inflammatory bowel disease patients in a population-based setting

Article Gastroenterology & Hepatology

From the American Epicenter: Coronavirus Disease 2019 in Patients with Inflammatory Bowel Disease in the New York City Metropolitan Area

Jordan E. Axelrad et al.

Summary: This case series study found that severe outcomes of COVID-19 after infection in patients with IBD were rare, and comparable to similarly aged individuals in the general population.

INFLAMMATORY BOWEL DISEASES (2021)

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Article Gastroenterology & Hepatology

Prevalence and Outcomes of COVID-19 Among Patients With Inflammatory Bowel Disease-A Danish Prospective Population-based Cohort Study

Mohamed Attauabi et al.

Summary: Patients with immune-mediated inflammatory diseases, including IBD, were less susceptible to COVID-19 compared to patients without such diseases, and use of immunosuppressive therapies or disease activity of IBD did not affect the disease course of COVID-19.

JOURNAL OF CROHNS & COLITIS (2021)

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Review Gastroenterology & Hepatology

Risk and outcomes of coronavirus disease in patients with inflammatory bowel disease: A systematic review and meta-analysis

Anupam Kumar Singh et al.

Summary: The risk of SARS-CoV-2 infection in patients with inflammatory bowel disease is comparable to the general population, with worse outcomes in ulcerative colitis, patients on steroids or 5-aminosalicylates, but better outcomes with biological agents.

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2021)

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Article Immunology

Coronavirus disease 2019, immune-mediated inflammatory diseases and immunosuppressive therapies-A Danish population-based cohort study

Mohamed Attauabi et al.

Summary: The study found a lower occurrence but a more severe disease course of COVID-19 among patients with IMIDs, associated with the use of systemic steroids and suspension of other immunosuppressants. Therefore, it emphasizes the importance of weighing risks before suspending immunosuppressants during COVID-19.

JOURNAL OF AUTOIMMUNITY (2021)

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Article Gastroenterology & Hepatology

Inflammatory bowel disease and risk of severe COVID-19: A nationwide population-based cohort study in Sweden

Jonas F. Ludvigsson et al.

Summary: While individuals with IBD were more likely to be admitted to hospital for COVID-19 than the general population, the risk of severe COVID-19 was not higher.

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2021)

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Article Immunology

Outcome of COVID-19 in hospitalized patients with chronic inflammatory diseases. A population based national register study in Denmark

Jens Kjeldsen et al.

Summary: The study found that hospitalized patients with COVID-19 and chronic inflammatory diseases did not have significantly increased length of hospital stay, had the same need for respiratory support devices (such as CPAP and mechanical ventilation), and had similar mortality rates compared to patients hospitalized with COVID-19 and no chronic inflammatory diseases.

JOURNAL OF AUTOIMMUNITY (2021)

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Article Medicine, General & Internal