Journal
PHYTOCHEMISTRY LETTERS
Volume 45, Issue -, Pages 157-160Publisher
ELSEVIER
DOI: 10.1016/j.phytol.2021.08.017
Keywords
Endophytic fungus; Stagonosporopsis oculihominis; Enantiomer; Spectroscopic analyses; Antibacterial activity
Categories
Funding
- Natural Science Key Research Program of Anhui Province University [KJ2020A0915]
- Foundation of Anhui Province Key Laboratory of Research & Development of Chinese Medicine [AKLPDCM202004]
- Natural Science Foundation of Anhui Province [2008085MH289]
- Anhui Province College Excellent Young Talents Fund [gxyqZD2019035]
- Major Science and Technology Projects in Anhui Province [18030801128]
Ask authors/readers for more resources
A successive investigation of the endophytic fungus Stagonosporopsis oculihominis isolated from Dendrobium huoshanense led to the discovery of two undescribed secondary metabolites, (+/-)-stagonosporopsin A and stagonosporopsin B, and a new natural product, stagonosporopsin C. Stagonosporopsin C exhibited moderate inhibitory activity against Staphylococcus aureus subsp. aureus ATCC29213 with an MIC50 value of 41.3 μM.
A successive investigation of the endophytic fungus Stagonosporopsis oculihominis isolated from Dendrobium huoshanense led to the discovery of two undescribed secondary metabolites, (+/-)-stagonosporopsin A and stagonosporopsin B, and a new natural product, stagonosporopsin C. (+/-)-stagonosporopsin A is a pair of enantiomer. The structures of the isolated compounds, including their absolute configurations, were elucidated based on extensive spectroscopic analyses, electronic circular dichroism (ECD) calculations and X-ray diffraction. Stagonosporopsin C exhibited moderate inhibitory activity against Staphylococcus aureus subsp. aureus ATCC29213 with an MIC50 value of 41.3 mu M.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
