New developments in MRI: System characterization, technical advances and radiotherapy applications

Article Radiology, Nuclear Medicine & Medical Imaging

Delta radiomics for rectal cancer response prediction using low field magnetic resonance guided radiotherapy: an external validation

Davide Cusumano et al.

Summary: The study confirmed the predictive value of ΔL-least and Δglnu features for clinical and pathological complete response in LARC patients, emphasizing the potential role of radiomics in MRgRT treatment.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Artificial Intelligence in magnetic Resonance guided Radiotherapy: Medical and physical considerations on state of art and future perspectives

Davide Cusumano et al.

Summary: The introduction of Magnetic Resonance-guided Radiotherapy (MRgRT) systems has significantly improved treatment with higher soft tissue contrast and real-time monitoring of tumor motion. Artificial Intelligence (AI) plays a key role in automating operations and applications in areas such as image segmentation, CT reconstruction, online planning, and predictive model development within MRgRT systems.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Investigating DWI changes in white matter of meningioma patients treated with proton therapy

Giulia Buizza et al.

Summary: This study evaluated changes in diffusion and perfusion-related properties of white matter (WM) induced by proton therapy, showing significant influence of dose and time on these properties and observing the impact of age, gender, and surgery extent on changes in ADC. The results suggest the potential for building normal tissue complication probability models using advanced imaging data to better integrate clinical and dose information.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Characterization of displacement forces and image artifacts in the presence of passive medical implants in low-field (<100 mT) permanent magnet-based MRI systems, and comparisons with clinical MRI systems

C. D. E. Van Speybroeck et al.

Summary: The study investigated the displacement forces and image artifacts associated with passive medical implants in low-field MRI systems (<100 mT) compared with higher field strengths. Results showed that displacement forces on all implants except the ferromagnetic one were between 1 and 10 mN at 50 mT, and image artifacts were much less at low-field compared to clinical field strengths. SAR simulations demonstrated that long echo train turbo spin echo sequences can be run within SAR limits under certain conditions.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

In phantom evaluation of targeting accuracy in MRI-based brain radiosurgery

S. Calusi et al.

Summary: The study aimed to determine the targeting accuracy of brain radiosurgery when planning procedures employing different MRI and MRI + CT combinations. The results showed that procedures using a combination of MR and CT images provide targeting accuracies comparable to those of MRI-only procedures, and the BrainTool proved to be a suitable tool for carrying out co-registration and targeting accuracy of Gamma Knife brain radiosurgery treatments.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

A role for magnetic susceptibility in synthetic computed tomography

Veronique Fortier et al.

Summary: This study introduces a method for generating synthetic CT using MRI-based susceptibility mapping to differentiate bone from air. The experiment successfully distinguished the skull, spine, teeth, and major sinuses in sCT from healthy volunteers and patients. The mean absolute CT number error between X-ray CT and sCT in patients ranged moderately, showing the potential of the proposed method for clinical applications.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

On the dependence of quantitative diffusion-weighted imaging on scanner system characteristics and acquisition parameters: A large multicenter and multiparametric phantom study with unsupervised clustering analysis

Luca Fedeli et al.

Summary: This multicenter phantom study assessed potential biases in ADC estimation due to different scanner characteristics using an innovative approach and unsupervised clustering analysis. The study found no significant dependence of in-center ADC values on acquisition plan/phase encoding direction and identified an association between measured ADC values and manufacturer/model of scanner. Several acquisition setups were shown to introduce different biases in ADC estimation.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

A novel phantom with dia- and paramagnetic substructure for quantitative susceptibility mapping and relaxometry

Julian Emmerich et al.

Summary: A phantom for experimental evaluation of QSM reconstruction algorithms was presented in this study. The phantom can separate isotropic dia- and paramagnetic susceptibility, with relaxation rates and susceptibility values generally coinciding with theoretical values under certain assumptions. This phantom may find application in the development and quantitative validation of current and future QSM reconstruction algorithms.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Artifact quantification of venous stents in the MRI environment: Differences between braided and laser-cut designs

Simon Reiss et al.

Summary: The study quantified and compared imaging artifacts induced by braided venous stents and laser-cut stents in MR imaging. Braided stents showed smaller frequency shifts and signal voids at 1.5 T compared to laser-cut stents, while differences in B-0 field distortions and B-1 distortions were observed between the two types of stents.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Quantification of magnetic susceptibility fingerprint of a 3D linearity medical device

T. Stanescu et al.

Summary: The study examines numerical modelling and experimental validation of magnetic susceptibility effects in a 3D linearity phantom for quantifying MR image distortions. By modeling the susceptibility signature of the device accurately, the procedure enables determination of GNL field and B-0 map without extra acquisitions or phantoms, after removing it as a post-processing correction step.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Empirical validation of gradient field models for an accurate ADC measured on clinical 3T MR systems in body oncologic applications

Yuxi Pang et al.

Summary: The study empirically verified the gradient nonlinearity characteristics provided by different vendors on 3T MR systems and demonstrated the effectiveness of GNL bias correction for human brain apparent diffusion coefficient (ADC). The results showed that accurate WM ADC was recovered using system-specific tensor-based GNL correction, regardless of spatial locations and clinical MR platforms.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

A new method for investigating osteoarthritis using Fast Field-Cycling nuclear magnetic resonance

Lionel M. Broche et al.

Summary: The study presents a novel MRI methodology, Fast Field-Cycling, to assess changes in critical proteins in human cartilage, offering potential for non-invasive monitoring of cartilage and evaluation of treatments for osteoarthritis.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

RESUMEN: A flexible class of multi-parameter qMRI protocols

Serena Monti et al.

Summary: The study introduces a class of fast 3D quantitative MRI schemes (RESUMEN) aimed at characterizing microstructural properties of brain tissues. The results show homogeneous and high SNR RESUMEN maps across the field-of-view, making them suitable for whole-brain acquisition in less than 15 minutes with isotropic voxel resolution of 700 micrometers.

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2021)

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Article Neurosciences