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GENES (2018)
Cyclooxygenase and lipoxygenase gene expression in the inflammogenesis of breast cancer
Brian M. Kennedy et al.
INFLAMMOPHARMACOLOGY (2018)
High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
In-geun Ryoo et al.
REDOX BIOLOGY (2018)
Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
Ron Shah et al.
ACS CENTRAL SCIENCE (2018)
Emerging cellular functions of the lipid metabolizing enzyme 15-Lipoxygenase-1
Melis Colakoglu et al.
CELL PROLIFERATION (2018)
MnSOD mediates shear stress-promoted tumor cell migration and adhesion
Shijun Ma et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
被撤回的出版物: Long non-coding RNA SNHG14 induces trastuzumab resistance of breast cancer via regulating PABPC1 expression through H3K27 acetylation (Retracted article. See vol. 42, 2023)
Huaying Dong et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases
Mingzhu Tang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium
Haider H. Dar et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase
Andrew Hinman et al.
PLOS ONE (2018)
3-Chloro-N′-(2-hydroxybenzylidene)benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy
Federica Sarno et al.
FRONTIERS IN PHARMACOLOGY (2018)
Breast cancer in postmenopausal women is associated with an altered gut metagenome
Jia Zhu et al.
MICROBIOME (2018)
Identification of a functional antioxidant response element at the HIF1A locus
Sarah E. Lacher et al.
REDOX BIOLOGY (2018)
Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors
Zheyu Shen et al.
ACS NANO (2018)
Transcriptional Regulation by Nrf2
Claudia Tonelli et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer
Daiha Shin et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells
Soumyadip Paul et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Whole Genome Transcriptome Analysis of the Association between Obesity and Triple-Negative Breast Cancer in Caucasian Women
Tarun K. K. Mamidi et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2018)
Statin drugs to reduce breast cancer recurrence and mortality
Colin H. Beckwitt et al.
BREAST CANCER RESEARCH (2018)
Cisplatin-Stitched Polysaccharide Vesicles for Synergistic Cancer Therapy of Triple Antagonistic Drugs
Nilesh Umakant Deshpande et al.
BIOMACROMOLECULES (2017)
Synthesis and cytotoxic activity of certain benzothiazole derivatives against human MCF-7 cancer cell line
Lamia W. Mohamed et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2017)
Hypoxia-inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
Gregg L. Semenza
EMBO JOURNAL (2017)
Lipid Osteoclastokines Regulate Breast Cancer Bone Metastasis
Jing Y. Krzeszinski et al.
ENDOCRINOLOGY (2017)
Coenzyme Q0 Enhances Ultraviolet B-Induced Apoptosis in Human Estrogen Receptor-Positive Breast (MCF-7) Cancer Cells
Hui-Min Wang et al.
INTEGRATIVE CANCER THERAPIES (2017)
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Valerian E. Kagan et al.
NATURE CHEMICAL BIOLOGY (2017)
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
Sebastian Doll et al.
NATURE CHEMICAL BIOLOGY (2017)
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
Shiro L. Cramer et al.
NATURE MEDICINE (2017)
Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism
A. Cacace et al.
ONCOGENE (2017)
Physical interaction of estrogen receptor with MnSOD: implication in mitochondrial O2•- upregulation and mTORC2 potentiation in estrogen-responsive breast cancer cells
M-U-D Lone et al.
ONCOGENE (2017)
RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations
Robert Shenkar et al.
STROKE (2017)
DuCLOX-2/5 inhibition: a promising target for cancer chemoprevention
Swetlana Gautam et al.
BREAST CANCER (2017)
Effects of physical activity on systemic oxidative/DNA status in breast cancer survivors
Barbara Tomasello et al.
ONCOLOGY LETTERS (2017)
Cadmium, arsenic, selenium and iron- Implications for tumor progression in breast cancer
E. Jablonska et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2017)
Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells
Chia-Han Tsai et al.
FOOD AND CHEMICAL TOXICOLOGY (2017)
Ten-eleven translocation 1 functions as a mediator of SOD3 expression in human lung cancer A549 cells
Tetsuro Kamiya et al.
FREE RADICAL RESEARCH (2017)
Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors
Sara Pizzamiglio et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells
Annapina Russo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Cardioprotective Effect of Dexrazoxane in Patients with HER2-Positive Breast Cancer Who Receive Anthracycline Based Adjuvant Chemotherapy Followed by Trastuzumab
In-Ho Kim et al.
JOURNAL OF BREAST CANCER (2017)
Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis
I. Aversa et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity
Brian Kawahara et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Clk1-regulated aerobic glycolsis is involved in glioma chemoresistance
Li Zhang et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Synergic prooxidant, apoptotic and TRPV1 channel activator effects of alpha-lipoic acid and cisplatin in MCF-7 breast cancer cells
Gokhan Nur et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2017)
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Vasanthi S. Viswanathan et al.
NATURE (2017)
Salinomycin kills cancer stem cells by sequestering iron in lysosomes
Trang Thi Mai et al.
NATURE CHEMISTRY (2017)
IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model
H. Kitamura et al.
ONCOGENE (2017)
Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis
T. C. Kenny et al.
ONCOGENE (2017)
VPS34 stimulation of p62 phosphorylation for cancer progression
X. Jiang et al.
ONCOGENE (2017)
ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner
D. Chen et al.
ONCOGENE (2017)
Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells
Shumei Ma et al.
PLOS ONE (2017)
Redox status in the sentinel lymph node of women with breast cancer
Maria Jesus Ramirez-Exposito et al.
UPSALA JOURNAL OF MEDICAL SCIENCES (2017)
Immunoexpression of lactoferrin in triple-negative breast cancer patients: A proposal to select a less aggressive subgroup
Antonio Ieni et al.
ONCOLOGY LETTERS (2017)
The role of quercetin and vitamin C in Nrf2-dependent oxidative stress production in breast cancer cells
Zohreh Mostafavi-Pour et al.
ONCOLOGY LETTERS (2017)
Comparison of the seleno-transcriptome expression between human non-cancerous mammary epithelial cells and two human breast cancer cell lines
Fabiola Rusolo et al.
ONCOLOGY LETTERS (2017)
The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
Chun-Shik Shin et al.
NATURE COMMUNICATIONS (2017)
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
Ya-fang Wang et al.
NATURE COMMUNICATIONS (2017)
CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway
Meng-Shian Chen et al.
ONCOTARGET (2017)
ALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia
Yungui Wang et al.
SCIENTIFIC REPORTS (2017)
EGLN1/c-Myc Induced Lymphoid-Specific Helicase Inhibits Ferroptosis through Lipid Metabolic Gene Expression Changes
Yiqun Jiang et al.
THERANOSTICS (2017)
Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis
Yang Jiang et al.
THERANOSTICS (2017)
Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective
Julia Chifman et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Pathway-based discovery of genetic interactions in breast cancer
Wen Wang et al.
PLOS GENETICS (2017)
Low-Dose Paclitaxel Inhibits Tumor Cell Growth by Regulating Glutaminolysis in Colorectal Carcinoma Cells
Chaoxiang Lv et al.
FRONTIERS IN PHARMACOLOGY (2017)
Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis
Z. Fan et al.
ONCOGENESIS (2017)
Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis
Jong-Lyel Roh et al.
REDOX BIOLOGY (2017)
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
Theodossis A. Theodossiou et al.
REDOX BIOLOGY (2017)
The down-regulation of SLC7A11 enhances ROS induced P-gp over-expression and drug resistance in MCF-7 breast cancer cells
Chun Ge et al.
SCIENTIFIC REPORTS (2017)
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization
Ryota Nakashima et al.
SCIENTIFIC REPORTS (2017)
Whey Protein Concentrate Renders MDA-MB-231 Cells Sensitive to Rapamycin by Altering Cellular Redox State and Activating GSK3β/mTOR Signaling
Shih-Hsuan Cheng et al.
SCIENTIFIC REPORTS (2017)
NFE2L2/NRF2 Activity Is Linked to Mitochondria and AMP-Activated Protein Kinase Signaling in Cancers Through miR-181c/Mitochondria-Encoded Cytochrome c Oxidase Regulation
Kyeong-Ah Jung et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Lipoxygenase-mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3
Ryosuke Shintoku et al.
CANCER SCIENCE (2017)
Haloperidol, a sigma receptor 1 antagonist, promotes ferroptosis in hepatocellular carcinoma cells
Tao Bai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Lipoxygenase inhibitors protect acute lymphoblastic leukemia cells from ferroptotic cell death
Lukas Probst et al.
BIOCHEMICAL PHARMACOLOGY (2017)
Synergistic anti-tumor activity of Nimotuzumab in combination with Trastuzumab in HER2-positive breast cancer
Yun Yang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction
Kevin Lu et al.
CANCER RESEARCH (2017)
HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
Shan Zhu et al.
CANCER RESEARCH (2017)
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
Xiaofang Sun et al.
HEPATOLOGY (2016)
Reactive Oxygen Species Mediate TNF-alpha Cytotoxic Effects in the Multidrug-Resistant Breast Cancer Cell Line MCF-7/MX
Morteza Ghandadi et al.
ONCOLOGY RESEARCH AND TREATMENT (2016)
Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma
Ser Yue Loo et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype
Xianghui Zou et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Autophagy promotes ferroptosis by degradation of ferritin
Wen Hou et al.
AUTOPHAGY (2016)
Iron participated in breast cancer chemoresistance by reinforcing IL-6 paracrine loop
Jing Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis
Luis Martinez et al.
BMC CANCER (2016)
Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer
Jong-Lyel Roh et al.
CANCER LETTERS (2016)
A Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase Pathway
Yan Jiang et al.
CANCER RESEARCH (2016)
Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
Sangbin Lim et al.
CANCER RESEARCH (2016)
Serum 5-LOX: a progressive protein marker for breast cancer and new approach for therapeutic target
Rahul Kumar et al.
CARCINOGENESIS (2016)
Ferroptosis: process and function
Y. Xie et al.
CELL DEATH AND DIFFERENTIATION (2016)
P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2
Marsha Rebecca Eno et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2016)
MicroRNA-153 Regulates NRF2 Expression and is Associated with Breast Carcinogenesis
Bo Wang et al.
CLINICAL LABORATORY (2016)
Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients
Tina Gruosso et al.
EMBO MOLECULAR MEDICINE (2016)
Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells
Katrin Gutsche et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model
Matthew Jennis et al.
GENES & DEVELOPMENT (2016)
Metallothionein-1G Facilitates Sorafenib Resistance Through Inhibition of Ferroptosis
Xiaofang Sun et al.
HEPATOLOGY (2016)
Co-encapsulation of paclitaxel and baicalein in nanoemulsions to overcome multidrug resistance via oxidative stress augmentation and P-glycoprotein inhibition
Luhua Meng et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Deferoxamine-induced increase in the intracellular iron levels in highly aggressive breast cancer cells leads to increased cell migration by enhancing TNF-α-dependent NF-κB signaling and TGF-β signaling
Ping Liu et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2016)
Redox homeostasis of breast cancer lineages contributes to differential cell death response to exogenous hydrogen peroxide
Fabio Hecht et al.
LIFE SCIENCES (2016)
Iron speciation, ferritin concentrations and Fe : ferritin ratios in different malignant breast cancer cell lines: on the search for cancer biomarkers
J. Alonso Garcia et al.
METALLOMICS (2016)
Mutational analysis of FANCJ helicase
Manhong Guo et al.
METHODS (2016)
Mitochondrial common deletion is elevated in blood of breast cancer patients mediated by oxidative stress
Hezhongrong Nie et al.
MITOCHONDRION (2016)
Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib
Aline Houessinon et al.
MOLECULAR CANCER (2016)
Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer
Evan C. Lien et al.
NATURE CELL BIOLOGY (2016)
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
Dawid Walerych et al.
NATURE CELL BIOLOGY (2016)
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
Kenichi Shimada et al.
NATURE CHEMICAL BIOLOGY (2016)
Regulated necrosis: disease relevance and therapeutic opportunities
Marcus Conrad et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance
A. L. Furfaro et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters
Merav Darash-Yahana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism
Samuel N. Rodman et al.
RADIATION RESEARCH (2016)
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
S. Ma et al.
CELL DEATH & DISEASE (2016)
NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction
Chao Zhang et al.
ONCOTARGET (2016)
Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity
Kenichi Shimada et al.
CELL CHEMICAL BIOLOGY (2016)
The multifaceted roles of fatty acid synthesis in cancer
Florian Roehrig et al.
NATURE REVIEWS CANCER (2016)
HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages
Oriana Marques et al.
CANCER MICROENVIRONMENT (2016)
The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis
Yang Liu et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2015)
Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer
Jessica A. Gibbons et al.
BMC CANCER (2015)
The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells
Christophe Louandre et al.
CANCER LETTERS (2015)
Elucidating Compound Mechanism of Action by Network Perturbation Analysis
Jung Hoon Woo et al.
CELL (2015)
Quantitative assessment of human serum transferrin receptor in breast cancer patients pre- and post-chemotherapy using peptide immunoaffinity enrichment coupled with targeted proteomics
Qingqing Xu et al.
CLINICA CHIMICA ACTA (2015)
Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment
Ganesh Venkatraman et al.
FASEB JOURNAL (2015)
Kalkitoxin Inhibits Angiogenesis, Disrupts Cellular Hypoxic Signaling, and Blocks Mitochondrial Electron Transport in Tumor Cells
J. Brian Morgan et al.
MARINE DRUGS (2015)
Neutrophils support lung colonization of metastasis-initiating breast cancer cells
Stefanie K. Wculek et al.
NATURE (2015)
Overexpression of Reactive Oxygen Species Scavenger Enzymes Is Associated with a Good Prognosis in Triple-Negative Breast Cancer
Darae Kim et al.
ONCOLOGY (2015)
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer
Fang Bai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer
Peter C. Hart et al.
NATURE COMMUNICATIONS (2015)
Expression of xCT and activity of system X-c(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress
Eric Habib et al.
REDOX BIOLOGY (2015)
Enhancement of ionizing radiation response by histamine in vitro and in vivo in human breast cancer
Diego J. Martinel Lamas et al.
CANCER BIOLOGY & THERAPY (2015)
Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hispanic and non-Hispanic white women: The breast cancer health disparities study
Avonne E. Connor et al.
MOLECULAR CARCINOGENESIS (2015)
Sequestosome 1/p62 facilitates HER2-induced mammary tumorigenesis through multiple signaling pathways
X. Cai-McRae et al.
ONCOGENE (2015)
The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
Yan Yu et al.
MOLECULAR & CELLULAR ONCOLOGY (2015)
Hepcidin and ferritin blood level as noninvasive tools for predicting breast cancer
R. Orlandi et al.
ANNALS OF ONCOLOGY (2014)
The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway
Rina Takamiya et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cells
Travis B. Salisbury et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol
Eva-Maria Kuech et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2014)
Antitumor Activity of Triterpenoid Saponin-Rich Adisia gigantifolia Extract on Human Breast Adenocarcinoma Cells in Vitro and in Vivo
Li-Hua Mu et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2014)
Oxidative stress in susceptibility to breast cancer: study in Spanish population
Patricia Rodrigues et al.
BMC CANCER (2014)
Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways
Bhupendra Singh et al.
CARCINOGENESIS (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Advances in Radical-Trapping Antioxidant Chemistry in the 21st Century: A Kinetics and Mechanisms Perspective
Keith U. Ingold et al.
CHEMICAL REVIEWS (2014)
Iron homeostasis and anemia markers in early breast cancer
Pierre-Jean Lamy et al.
CLINICA CHIMICA ACTA (2014)
Mechanistic Insight of Drug Resistance with Special Focus on Iron in Estrogen Receptor Positive Breast Cancer
Rashmi Mittal et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2014)
Hormone Responsive Breast Cancer and BRCA1 Mutation: Mechanism, Regulation and Iron-mediated Effects
Abdulrazzaq N. Zghair et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2014)
Estrogen increases Nrf2 activity through activation of the PI3K pathway in MCF-7 breast cancer cells
Juanjuan Wu et al.
EXPERIMENTAL CELL RESEARCH (2014)
Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death
Katherine L. Cook et al.
FASEB JOURNAL (2014)
Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms
Anantha Koteswararao Kanugula et al.
FEBS JOURNAL (2014)
Natural Antioxidants Exhibit Chemopreventive Characteristics through the Regulation of CNC b-Zip Transcription Factors in Estrogen-Induced Breast Carcinogenesis
Anwesha Chatterjee et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2014)
A Novel CXCR3-B Chemokine Receptor-induced Growth-inhibitory Signal in Cancer Cells Is Mediated through the Regulation of Bach-1 Protein and Nrf2 Protein Nuclear Translocation
Murugabaskar Balan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
SOD2 to SOD1 Switch in Breast Cancer
Luena Papa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Role of inflammation and oxidative stress in post-menopausal oestrogen-dependent breast cancer
Clelia Madeddu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2014)
Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival
Juan M. Funes et al.
MOLECULAR CANCER (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
CISD2 expression is a novel marker correlating with pelvic lymph node metastasis and prognosis in patients with early-stage cervical cancer
Luxin Liu et al.
MEDICAL ONCOLOGY (2014)
Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis
M. L. Teoh-Fitzgerald et al.
ONCOGENE (2014)
The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells
Daniela Carlisi et al.
ONCOLOGY REPORTS (2014)
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
Antonio Ayala et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
The Sensitivity of Cancer Cells to Pheophorbide a-Based Photodynamic Therapy Is Enhanced by NRF2 Silencing
Bo-hyun Choi et al.
PLOS ONE (2014)
The pharmacology of statins
Cesare R. Sirtori
PHARMACOLOGICAL RESEARCH (2014)
The ErbB/HER family of protein-tyrosine kinases and cancer
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2014)
Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway
Chiara Gorrini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
John D. Hayes et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction
Hyo Jin Kang et al.
SCIENTIFIC REPORTS (2014)
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Scott J. Dixon et al.
ELIFE (2014)
Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3
Chu-An Wang et al.
BREAST CANCER RESEARCH (2014)
Nrf2 is associated with the regulation of basal transcription activity of the BRCA1 gene
Qiaoqiao Wang et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2013)
ROS-Mediated Lipid Peroxidation and RES-Activated Signaling
Edward E. Farmer et al.
ANNUAL REVIEW OF PLANT BIOLOGY, VOL 64 (2013)
Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer
Bhupendra Singh et al.
BMC CANCER (2013)
Ferritin stimulates breast cancer cells through an iron-independent mechanism and is localized within tumor-associated macrophages
Ahmed A. Alkhateeb et al.
BREAST CANCER RESEARCH AND TREATMENT (2013)
Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells
H. Li et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
The role of vascular epithelial growth factor receptor-tyrosine kinase inhibitors in the treatment of advanced breast cancer: a meta-analysis of 12 randomized controlled trials
Jianwen Li et al.
CURRENT MEDICAL RESEARCH AND OPINION (2013)
Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib
Christophe Louandre et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin
Vasyl F. Chekhun et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
Igor P. Pogribny et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Oxidative Stress in Alzheimer's Disease and Mild Cognitive Impairment with High Sensitivity and Specificity
Natividad Lopez et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability
Sanjay Kumar Bharti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Cancer-Produced Metabolites of 5-Lipoxygenase Induce Tumor-Evoked Regulatory B Cells via Peroxisome Proliferator-Activated Receptor α
Katarzyna Wejksza et al.
JOURNAL OF IMMUNOLOGY (2013)
Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis
Z-H Wen et al.
ONCOGENE (2013)
Fatty Acid Metabolites in Rapidly Proliferating Breast Cancer
Joseph T. O'Flaherty et al.
PLOS ONE (2013)
Association between Polymorphisms in Glutathione Peroxidase and Selenoprotein P Genes, Glutathione Peroxidase Activity, HRT Use and Breast Cancer Risk
Catherine Meplan et al.
PLOS ONE (2013)
Non-Invasive In Vivo Imaging of Near Infrared-labeled Transferrin in Breast Cancer Cells and Tumors Using Fluorescence Lifetime FRET
Ken Abe et al.
PLOS ONE (2013)
NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth
Yang-Sung Sohn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Role of arachidonic acid metabolism in Stat5 activation induced by oleic acid in MDA-MB-231 breast cancer cells
Adriana Soto-Guzman et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2013)
A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways
Fei-Fei Gan et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
The aryl hydrocarbon receptor and estrogen receptor alpha differentially modulate nuclear factor erythroid-2-related factor 2 transactivation in MCF-7 breast cancer cells
Raymond Lo et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Manganese superoxide dismutase promotes anoikis resistance and tumor metastasis
S. Kamarajugadda et al.
CELL DEATH & DISEASE (2013)
Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells
Nathalia Serna-Marquez et al.
CELLULAR ONCOLOGY (2013)
Polyphenols, isothiocyanates, and carotenoid derivatives enhance estrogenic activity in bone cells but inhibit it in breast cancer cells
Anna Veprik et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Combating the Drug Resistance of Cisplatin Using a Platinum Prodrug Based Delivery System
Yuanzeng Min et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Pitavastatin, a new HMG-CoA reductase inhibitor, induces phototoxicity in human keratinocytes NCTC-2544 through the formation of benzophenanthridine-like photoproducts
Giampietro Viola et al.
ARCHIVES OF TOXICOLOGY (2012)
Glutathione levels in human tumors
Michael P. Gamcsik et al.
BIOMARKERS (2012)
Differential oxidative status and immune characterization of the early and advanced stages of human breast cancer
C. Panis et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles
Abena S. Agyeman et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Elevated mRNA expression of CHAC1 splicing variants is associated with poor outcome for breast and ovarian cancer patients
G. Goebel et al.
BRITISH JOURNAL OF CANCER (2012)
Pleiotropic effects of pitavastatin
Jean Davignon
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study
Joanne Kotsopoulos et al.
CANCER CAUSES & CONTROL (2012)
Induction of NAD(P)H-quinone oxidoreductase 1 by antioxidants in female ACI rats is associated with decrease in oxidative DNA damage and inhibition of estrogen-induced breast cancer
Bhupendra Singh et al.
CARCINOGENESIS (2012)
Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage and is associated with inhibition of estrogen-induced breast cancer
Bhupendra Singh et al.
CARCINOGENESIS (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: Novel iron chelators with selective antiproliferative action
Eliska Mackova et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2012)
Mammalian proapoptotic factor ChaC1 and its homologues function as γ-glutamyl cyclotransferases acting specifically on glutathione
Akhilesh Kumar et al.
EMBO REPORTS (2012)
Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain
Si-Eun Yoo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Association of superoxide dismutases and NAD(P)H quinone oxidoreductases with prognosis of patients with breast carcinomas
Miluse Hubackova et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
The Functional Interaction between Acyl-CoA Synthetase 4, 5-Lipooxygenase and Cyclooxygenase-2 Controls Tumor Growth: A Novel Therapeutic Target
Ulises D. Orlando et al.
PLOS ONE (2012)
Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages
Nobuhiko Harada et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Evaluation of human LOX-12 as a serum marker for breast cancer
Abhay Kumar Singh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Role of ferritin alterations in human breast cancer cells
Svitlana I. Shpyleva et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism
Muhua Yang et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization
Lydia W. S. Finley et al.
CANCER CELL (2011)
Low Plasma Coenzyme Q10 Levels and Breast Cancer Risk in Chinese Women
Robert V. Cooney et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2011)
An Iron Regulatory Gene Signature Predicts Outcome in Breast Cancer
Lance D. Miller et al.
CANCER RESEARCH (2011)
Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid
Gail E. Grant et al.
CARCINOGENESIS (2011)
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
Jesper Z. Haeggstrom et al.
CHEMICAL REVIEWS (2011)
Hepcidin: A novel peptide hormone regulating iron metabolism
Bhawna Singh et al.
CLINICA CHIMICA ACTA (2011)
Effects of iron deficiency and iron overload on angiogenesis and oxidative stress-a potential dual role for iron in breast cancer
Jinlong Jian et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Regulation of the high basal expression of the manganese superoxide dismutase gene in aggressive breast cancer cells
Marie Ennen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
miR-200a Regulates Nrf2 Activation by Targeting Keap1 mRNA in Breast Cancer Cells
Gabriel Eades et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel Function of Transcription Factor Nrf2 as an Inhibitor of RON Tyrosine Kinase Receptor-mediated Cancer Cell Invasion
Amalraj Thangasamy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species
Santhi Achuthan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse
Dontscho Kerjaschki et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Expression of manganese superoxide dismutase in patients with breast cancer
Shih-Meng Tsai et al.
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES (2011)
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
E. L. Bell et al.
ONCOGENE (2011)
Association of a functional polymorphism (Gln261Arg) in 12-lipoxygenase with breast cancer
Vidudala V. T. S. Prasad et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2011)
Differential Expression of Transferrin Receptor (TfR) in a Spectrum of Normal to Malignant Breast Tissues: Implications for In Situ and Invasive Carcinoma
Meenakshi Singh et al.
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2011)
Nrf2-regulated PPARγ Expression Is Critical to Protection against Acute Lung Injury in Mice
Hye-Youn Cho et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)
Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer
Yuan Yao et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Impaired expression of glutathione peroxidase-4 gene in peripheral blood mononuclear cells: A biomarker of increased breast cancer risk
G. Bermano et al.
CANCER BIOMARKERS (2010)
Plasma Coenzyme Q10 Levels and Postmenopausal Breast Cancer Risk: The Multiethnic Cohort Study
Weiwen Chai et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2010)
Hepcidin and iron metabolism: From laboratory to clinical implications
Massimo Franchini et al.
CLINICA CHIMICA ACTA (2010)
Antioxidant status and lipid peroxidation in the blood of breast cancer patients of different ages after chemotherapy with 5-fluorouracil, doxorubicin and cyclophosphamide
Jelena Kasapovic et al.
CLINICAL BIOCHEMISTRY (2010)
Proteomic Profiling of Mammary Carcinomas Identifies C7orf24, a γ-Glutamyl Cyclotransferase, as a Potential Cancer Biomarker
Pavel Gromov et al.
JOURNAL OF PROTEOME RESEARCH (2010)
Ferritin levels, inflammatory biomarkers, and mortality in peripheral arterial disease: A substudy of the Iron (Fe) and Atherosclerosis Study (FeAST) Trial
Ralph G. DePalma et al.
JOURNAL OF VASCULAR SURGERY (2010)
Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress
Randa Tao et al.
MOLECULAR CELL (2010)
Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model
Massih Bahar et al.
NUTRITION JOURNAL (2010)
Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis
Zandra K. Pinnix et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
The Akt-SREBP nexus: cell signaling meets lipid metabolism
James R. Krycer et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase IIα in Breast Cancer Cells
V. Ashutosh Rao et al.
CANCER RESEARCH (2009)
Overexpression of Extracellular Superoxide Dismutase Attenuates Heparanase Expression and Inhibits Breast Carcinoma Cell Growth and Invasion
Melissa L. T. Teoh et al.
CANCER RESEARCH (2009)
Identification of DDB2 Protein as a Transcriptional Regulator of Constitutive SOD2 Gene Expression in Human Breast Cancer Cells
Vanessa Minig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Improved Survival in Patients with End-stage Cancer Treated with Coenzyme Q10 and Other Antioxidants: a Pilot Study
N. Hertz et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2009)
Catechol estrogens mediated activation of Nrf2 through covalent modification of its quinone metabolite to Keap1
Daigo Sumi et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2009)
Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy
Martin Loignon et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Gene expression profiling of the tumor microenvironment during breast cancer progression
Xiao-Jun Ma et al.
BREAST CANCER RESEARCH (2009)
NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
Guang-Hui Liu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Antiangiogenic and hypolipidemic activity of coenzyme Q(10) supplementation to breast cancer patients undergoing Tamoxifen therapy
Panchanatham Sachdanandam
BIOFACTORS (2008)
Roles of hormone replacement therapy, and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status
Jisen Dai et al.
BREAST (2008)
Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy
Vummidi Giridhar Premkumar et al.
BRITISH JOURNAL OF NUTRITION (2008)
Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1
Eiji Furuta et al.
CANCER RESEARCH (2008)
Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane
Mebrahtu B. Sibhatu et al.
CARCINOGENESIS (2008)
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
Thomas Porstmann et al.
CELL METABOLISM (2008)
Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion-associated cardiac dysfunction
Erinne R. Dabkowski et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Molecular-Targeted Antitumor Agents. 19. Furospongolide from a Marine Lendenfeldia sp Sponge Inhibits Hypoxia-Inducible Factor-1 Activation in Breast Tumor Cells
Yang Liu et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Effects of Cu/Zn superoxide dismutase on estrogen responsiveness and oxidative stress in human breast cancer cells
Abhi K. Rao et al.
MOLECULAR ENDOCRINOLOGY (2008)
Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth
Zilal Kattan et al.
PLOS ONE (2008)
Discovery essential of a lysophospholipid acyltransferase family for membrane asymmetry and diversity
Daisuke Hishikawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Augmented antioxidant status in Tamoxifen treated postmenopausal women with breast cancer on co-administration with Coenzyme Q10, Niacin and Riboflavin
Srinivasan Yuvaraj et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)
Role of manganese superoxide dismutase on growth and invasive properties of human estrogen-independent breast cancer cells
Zilal Kattan et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells
Kip M. Connor et al.
CANCER RESEARCH (2007)
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
Javier A. Menendez et al.
NATURE REVIEWS CANCER (2007)
The nuclear matrix protein, NRP/B, enhances Nrf2-mediated oxidative stress responses in breast cancer cells
Seyha Seng et al.
CANCER RESEARCH (2007)
Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer
Miriam Udler et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda et al.
NATURE (2007)
Serum cytokine levels of interleukin-1β, -6, -8, tumour necrosis factor-α and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q10, riboflavin and niacin
Vummidi Giridhar Premkumar et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2007)
Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy
Vummidi Giridhar Premkumar et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2007)
Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation
Ian J. Sipula et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2006)
Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion
William O. Osburn et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)
Interactions between genes involved in the antioxidant defence system and breast cancer risk
M. Z. Oestergaard et al.
BRITISH JOURNAL OF CANCER (2006)
Overexpression of manganese or copper-zinc superoxide dismutase inhibits breast cancer growth
Christine J. Weydert et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Glycogen synthase kinase-3β inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2
Maria Salazar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines
G Brea-Calvo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Reduction of isoforms of 15-lipoxygenase (15-LOX)-1 and 15-LOX-2 in human breast cancer
WG Jiang et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2006)
Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose
KK Andringa et al.
CANCER RESEARCH (2006)
Therapeutic potential of superoxide dismutase (SOD) for resolution of inflammation
K. Yasui et al.
INFLAMMATION RESEARCH (2006)
Structural biology of mammalian lipoxygenasese enzymatic consequences of targeted alterations of the protein structure
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1α and vascular endothelial growth factor
M Wang et al.
ONCOGENE (2005)
PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP
T Porstmann et al.
ONCOGENE (2005)
Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-κB and AP-1
HP Yang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Therapeutic effect of tamoxifen and energy-modulating vitamins on carbohydrate-metabolizing enzymes in breast cancer
SS Perumal et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2005)
Combined efficacy of tamoxifen and coenzyme Q10 on the status of lipid peroxidation and antioxidants in DMBA induced breast cancer
SS Perumal et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2005)
Augmented efficacy of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin, niacin, and CoQ10:: Effects on lipid peroxidation and antioxidants in mitochondria
SS Perumal et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2005)
Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2α expression during progression of breast cancer
DB Douglas et al.
CANCER RESEARCH (2004)
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
DD Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors
T Kubota et al.
BIOCHEMICAL PHARMACOLOGY (2004)
BRCA1 induces antioxidant gene expression and resistance to oxidative stress
I Bae et al.
CANCER RESEARCH (2004)
Invasive potential induced under long-term oxidative stress in mammary epithelial cells
K Mori et al.
CANCER RESEARCH (2004)
Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anti-cancer iron chelator
R Zhao et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Overexpression of ErbB2 enhances ethanol-stimulated intracellular signaling and invasion of human mammary epithelial and breast cancer cells in vitro
CL Ma et al.
ONCOGENE (2003)
Pharmacogenetics of estrogen metabolism and transport in relation to cancer
NJ Lakhani et al.
CURRENT DRUG METABOLISM (2003)
Estrogen regulation of transferrin gene expression in MCF-7 human breast cancer cells
C. Vyhlidal et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2002)
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
H Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells
WG Tong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Synthesis, structure, spectroscopic and in vitro antitumour studies of a novel gallium(III) complex with 2-acetylpyridine 4N-dimethylthiosemicarbazone
VB Arion et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2002)
Conditional derepression of ferritin synthesis in cells expressing a constitutive IRP1 mutant
J Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Hyperresistance to cholesterol hydroperoxide-induced peroxidative injury and apoptotic death in a tumor cell line that overexpresses glutathione peroxidase isotype-4
R Hurst et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc- cystine transporter:: a new action for an old drug
PW Gout et al.
LEUKEMIA (2001)
p53-independent apoptosis mediated by tachpyridine, an anti-cancer iron chelator
RD Abeysinghe et al.
CARCINOGENESIS (2001)
Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy
HP Wang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
JY Chan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
Plasma coenzyme Q10 in children and adolescents undergoing doxorubicin therapy
S Eaton et al.
CLINICA CHIMICA ACTA (2000)
Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients
O Portakal et al.
CLINICAL BIOCHEMISTRY (2000)
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
T Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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