4.7 Article

Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Prenatal dexamethasone exposure induces nonalcoholic fatty liver disease in male rat offspring via the miR-122/YY1/ACE2-MAS1 pathway

Heze Liu et al.

Summary: Studies have demonstrated that prenatal dexamethasone exposure can lead to nonalcoholic fatty liver disease in adult male rat offspring, with mechanisms including inhibition of miR-122 expression, increased YY1 expression, and inhibition of the ACE2-MAS1 signaling pathway, resulting in increased hepatic triglyceride synthesis and decreased oxidative function.

BIOCHEMICAL PHARMACOLOGY (2021)

Article Pharmacology & Pharmacy

Low-activity programming of the PDGFRβ/FAK pathway mediates H-type vessel dysplasia and high susceptibility to osteoporosis in female offspring rats after prenatal dexamethasone exposure

Yangfan Shangguan et al.

Summary: Research has shown that prenatal dexamethasone exposure may lead to osteoporosis in female offspring, affecting bone mass and H-type vessel formation, with mechanisms involving low-activity programming of the PDGFRα/FAK pathway.

BIOCHEMICAL PHARMACOLOGY (2021)

Article Pharmacology & Pharmacy

miR-148a/LDLR mediates hypercholesterolemia induced by prenatal dexamethasone exposure in male offspring rats

Li Li et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2020)

Review Biochemistry & Molecular Biology

Mechanisms for establishment of the placental glucocorticoid barrier, a guard for life

Ping Zhu et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Review Biochemistry & Molecular Biology

Genomic imprinting and its effects on postnatal growth and adult metabolism

Steven J. Millership et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Article Pharmacology & Pharmacy

cAMP/PKA/EGR1 signaling mediates the molecular mechanism of ethanol-induced inhibition of placental 11β-HSD2 expression

Luting Yu et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2018)

Article Multidisciplinary Sciences

Sex-specific gene-environment interactions underlying ASD-like behaviors

Sara M. Schaafsma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Peripheral Vascular Disease

11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome

Matthew A. Bailey

CURRENT HYPERTENSION REPORTS (2017)

Review Medicine, Research & Experimental

Gender differences in developmental programming of cardiovascular diseases

John Henry Dasinger et al.

CLINICAL SCIENCE (2016)

Article Endocrinology & Metabolism

Sex-Dimorphic Effects of Prenatal Treatment With Dexamethasone

Lena Wallensteen et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

Review Physiology

Sex differences in the developmental programming of hypertension

N. B. Ojeda et al.

ACTA PHYSIOLOGICA (2014)

Review Endocrinology & Metabolism

Glucocorticoids and fetal programming part 1: outcomes

Vasilis G. Moisiadis et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Review Endocrinology & Metabolism

Glucocorticoids and fetal programming part 2: mechanisms

Vasilis G. Moisiadis et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Article Endocrinology & Metabolism

Critical Role of Histone Acetylation by p300 in Human Placental 11β-HSD2 Expression

Jianneng Li et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Obstetrics & Gynecology

Growth and insulin dynamics in two generations of female offspring of mothers receiving a single course of synthetic glucocorticoids

Nathan M. Long et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2012)

Article Endocrinology & Metabolism

Impact of Antenatal Synthetic Glucocorticoid Exposure on Endocrine Stress Reactivity in Term-Born Children

Nina Alexander et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Article Psychology, Developmental

Sex moderates associations between prenatal glucocorticoid exposure and human fetal neurological development

Laura M. Glynn et al.

DEVELOPMENTAL SCIENCE (2012)

Article Biochemistry & Molecular Biology

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

Elmar W. Tobi et al.

HUMAN MOLECULAR GENETICS (2009)

Article Endocrinology & Metabolism

Identification and developmental changes of aromatase and estrogen receptor expression in prepubertal and pubertal human adrenal tissues

Maria Sonia Baquedano et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Review Medicine, General & Internal

Sexual dysfunction 3 - Sexual dysfunction in men and women with endocrine disorders

Shalender Bhasin et al.

LANCET (2007)

Review Endocrinology & Metabolism

GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release

EJ Filardo et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2005)

Article Biochemistry & Molecular Biology

Cell- and ligand-specific regulation of promoters containing activator protein-1 and sp1 sites by estrogen receptors α and β

JR Schultz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Endocrinology & Metabolism

Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology

D O'Regan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Multidisciplinary Sciences

A transgenic model of visceral obesity and the metabolic syndrome

H Masuzaki et al.

SCIENCE (2001)

Article Biochemistry & Molecular Biology

Ligand-, cell-, and estrogen receptor subtype (α/β)-dependent activation at GC-rich (Sp1) promoter elements

B Saville et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Medicine, Research & Experimental

Antenatal corticosteroid therapy and blood pressure at 14 years of age in preterm children

LW Doyle et al.

CLINICAL SCIENCE (2000)