Hepatitis C Virus Treatment Response to Direct-acting Antivirals Among Adolescents With HIV/HCV Coinfection: Real-world Data From Ukraine

Article Immunology

Effectiveness and Safety of Interferon-Free Direct-Acting Antiviral Hepatitis C Virus Therapy in HIV/Hepatitis C Virus Coinfected Individuals: Results From a Pan-European Study

Sarah Amele et al.

Summary: The study in Europe on HIV/HCV coinfected individuals showed that DAAs treatment is well tolerated, with high rates of SVR12 achievable in all regions.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2021)

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Article Gastroenterology & Hepatology

Efficacy of Sofosbuvir/Ledipasvir in Adolescents With Chronic Hepatitis C Genotypes 1, 3, and 4: A Real-world Study

Daniele Serranti et al.

Summary: This study aimed to evaluate the efficacy and safety of Sofosbuvir/Ledipasvir in adolescents with chronic hepatitis C. The results showed high efficacy and optimal safety profile of SOF/LDV in treating CHC in adolescents, with a SVR12 rate of 98.7% and no severe adverse events observed.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2021)

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Review Gastroenterology & Hepatology

Where are the children in national hepatitis C policies? A global review of national strategic plans and guidelines

Farihah Malik et al.

Summary: This study highlighted significant gaps in policies for testing and treating HCV-infected children and adolescents in many countries, emphasizing the urgent need for advocacy and updated guidelines specific to this population.

JHEP REPORTS (2021)

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Article Gastroenterology & Hepatology