Study of the Early Telencephalon Genes of Cyclostomes as a Way to Restoring the Evolutionary History of This Unique Part of the Central Nervous System of Vertebrates

The telencephalon, which provides the highest forms of nervous activity in humans and other animals, is one of the most important innovations of vertebrates. Although this part of the brain has been described in all living vertebrates, its evolutionary origin is still poorly understood. This article discusses one of the possible approaches to studying the expression and functional properties of genes that regulate the early development of the forebrain in cyclostomes (lampreys) as the most archaic representatives of vertebrates. The results of studies of genes such as Anf, FoxG1, and genes of the Noggin family are described.

Automated summary

The telencephalon, crucial for high forms of nervous activity in vertebrates, remains a poorly understood evolutionary origin. This article explores the study of gene expression and functional properties in cyclostomes to shed light on the early development of the forebrain. Results of genes such as Anf, FoxG1, and Noggin family genes are discussed.