Journal
OSTEOARTHRITIS AND CARTILAGE
Volume 30, Issue 1, Pages 32-41Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.joca.2021.09.010
Keywords
Hip osteoarthritis; Knee osteoarthritis; Non-surgical treatments; Exercise
Categories
Funding
- National Health and Medical Research Council (NHMRC) Investigator Grant Emerging Leader 1 [1172928]
- NHMRC Senior Research Fellowship [1154217]
- NHMRC Investigator Grant Leadership 2 [1174431]
- NIHR CRN (Clinical Research Networks) West Midlands Research Scholarship
- Haywood Foundation
- National Health and Medical Research Council of Australia [1172928, 1174431] Funding Source: NHMRC
Ask authors/readers for more resources
Hip and knee osteoarthritis have distinct characteristics in terms of prevalence, pathophysiology, clinical presentation, and treatment. Researchers should focus on the specificity of hip OA to develop more effective treatments.
Hip and knee osteoarthritis (OA) are leading causes of global disability. Most research to date has focused on the knee, with results often extrapolated to the hip, and this extends to treatment recommendations in clinical guidelines. Extrapolating results from research on knee OA may limit our understanding of disease characteristics specific to hip OA, thereby constraining development and implementation of effective treatments. This review highlights differences between hip and knee OA with respect to prevalence, prognosis, epigenetics, pathophysiology, anatomical and biomechanical factors, clinical presentation, pain and non-surgical treatment recommendations and management. (c) 2021 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
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