Journal
ORGANIC LETTERS
Volume 23, Issue 20, Pages 7851-7854Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c02873
Keywords
-
Categories
Funding
- National Key Research and Development Program [2019YFA0905700]
- National Natural Science Foundation of China [31970065, 31770104, U1902214]
- Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project [TSBICIP-KJGG002]
- Yunnan Key Research and Development Program [2019ZF011-2]
Ask authors/readers for more resources
In this study, three glycosyltransferases involved in the biosynthesis of a complex acylated phenolic glycoside in Ligustrum robustum were characterized. These enzymes expand the toolbox for synthesizing natural products with various sugar chains.
In this study, we report the characterization of three glycosyltransferases involved in the biosynthesis of ligupurpuroside B, a complex acylated phenolic glycoside in Ligustrum robustum. UGT85AF8 catalyzed the formation of salidroside from tyrosol. UGT79G7, an osmanthuside A 1,3-rhamnosyltransferase, and UGT79A19, an osmanthuside B 1,4-rhamnosyltransferase, sequentially converted osmanthuside A into ligupurpuroside B. Orthologs of UGT79G7 were also discovered from other plants producing verbascoside. These rhamnosyltransferases expand the toolbox for the biosynthesis of natural products with various sugar chains.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
