4.8 Article

Ruthenium-Catalyzed Dual Dehydrogenative Silylation of C(sp3)-H Bonds: Access to Diverse Silicon-Centered Spirocycles

Journal

ORGANIC LETTERS
Volume 23, Issue 19, Pages 7603-7607

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c02821

Keywords

-

Funding

  1. National Natural Science Foundation of China [22072178, 21825109, 21821002, 21732006]
  2. National Basic Research Program of China [2016YFA0202900]
  3. Strategic Priority Research Program of Chinese Academy of Sciences [XDB20000000]
  4. K. C. Wong Education Foundation
  5. Ningbo Municipal Bureau of Science and Technology [2019B10096]

Ask authors/readers for more resources

In this study, a pincer Ru-catalyzed dual intramolecular dehydrogenative silylation of primary C(sp(3))-H bonds was reported. The reaction demonstrated high efficiency, scalability, and good functional group tolerance, allowing for facile and atom-economical access to structurally diverse silicon-centered spirocycles, including unprecedented oxa-spirosilabiindanes and aza-spirosilabiindanes.
We report herein a pincer Ru-catalyzed dual intramolecular dehydrogenative silylation of primary C(sp(3))-H bonds. The reaction features high efficiency, scalability, and good functional group tolerance, allowing a facile and atom-economical access to structurally diverse silicon-centered spirocycles, including unprecedented oxa-spirosilabiindanes and aza-spirosilabiindanes.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available