4.6 Article

Optical phased array neural probes for beam-steering in brain tissue

Journal

OPTICS LETTERS
Volume 47, Issue 5, Pages 1073-1076

Publisher

OPTICAL SOC AMER
DOI: 10.1364/OL.441609

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Funding

  1. National Institutes of Health [NS090596, NS099726]
  2. Canadian Institutes of Health Research
  3. Natural Sciences and Engineering Research Council of Canada
  4. Caltech Kavli Nanoscience Institute

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This article introduces implantable silicon neural probes with integrated optical phased arrays and demonstrates optical beam steering in vitro. The formation of beams in brain tissue is simulated and characterized, and the probes are used for optogenetic stimulation and calcium imaging.
Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue is simulated and characterized. The probes are used for optogenetic stimulation and calcium imaging. (C) 2022 Optical Society of America

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