4.2 Review

The use of hydroxyapatite toothpaste to prevent dental caries

Journal

ODONTOLOGY
Volume 110, Issue 2, Pages 223-230

Publisher

SPRINGER
DOI: 10.1007/s10266-021-00675-4

Keywords

Hydroxyapatite; Oral care; Enamel; Toothpaste

Funding

  1. National Science and Engineering Research Council (NSERC) of Canada [RGPIN-2019-07070]

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This narrative review aims to summarize recent findings on the remineralization potential of HAP toothpaste in vitro, in situ, and in vivo, as well as other applications in dentistry.
Dissolution of hydroxyapatite from the tooth structure at low pH can lead to the irreversible destruction of enamel and dentin, which if left untreated can result in pain and tooth loss. Hydroxyapatite toothpastes contain hydroxyapatite particles in micro- or nanocrystalline form that have been shown to deposit and restore demineralized enamel surfaces. As such, they are currently being explored as a fluoride-free anti-caries agent. This narrative review article aims to summarize the recent findings of the research investigating the remineralization potential of HAP toothpaste in vitro, in situ and in vivo, as well as some other applications in dentistry.

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