Diets high in glycemic index and glycemic load are associated with an increased risk of metabolic syndrome among Korean women

Background and aims: Accurate estimation of the glycemic index (GI) and glycemic load (GL) of diets is essential when assessing health implications of dietary GI and GL. The present study aimed to estimate dietary GI and GL utilizing the updated GI tables with a large number of new, reliable GI values and assess their associations with metabolic syndrome among Korean adults. Methods and results: We analyzed data from 3317 men and 6191 women for this cross-sectional study. Dietary intake was assessed with a validated food frequency questionnaire. Metabolic syndrome and its components were defined based on the harmonized criteria with Korean-specific cutoffs for waist circumference. Multivariate logistic regression was used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Compared with women in the lowest quintiles of energy-adjusted dietary GI and GL, women in the highest quintiles had significantly greater risks of metabolic syndrome (GI, OR Z 1.56, 95% CI Z 1.18-2.06; GL, OR Z 1.80, 95% CI Z 1.27-2.57), elevated blood pressure, reduced high-density lipoprotein cholesterol (HDL-C, both GI and GL), elevated triglycerides (GI only), elevated waist circumference, and elevated fasting glucose (GL only). Among men, no significant association was noted except for a higher risk of reduced HDL-C (OR Z 1.59, 95% CI Z 1.01-2.29) in the highest quintile of energy-adjusted dietary GI than in the lowest quintile. Conclusion: Our findings suggest that dietary GI and GL are positively associated with metabolic syndrome risk among women, but not men, in Korea. (C) 2022 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Automated summary

This study estimated dietary glycemic index (GI) and glycemic load (GL) using updated GI tables and found a positive association between dietary GI and GL and the risk of metabolic syndrome among women in Korea.