4.8 Article

Nanobase.org: a repository for DNA and RNA nanostructures

Journal

NUCLEIC ACIDS RESEARCH
Volume 50, Issue D1, Pages D246-D252

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkab1000

Keywords

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Funding

  1. National Science Foundation [1931487]
  2. Office of Advanced Cyberinfrastructure (OAC)
  3. Direct For Computer & Info Scie & Enginr [1931487] Funding Source: National Science Foundation

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The database is an online resource for nucleic acid nanostructures, providing an upload interface, searching and database browsing capabilities. It includes conversion tools to encourage design file conversion, aiming to facilitate sharing and reuse of designs in the DNA/RNA nanotechnology community.
We introduce a new online database of nucleic acid nanostructures for the field of DNA and RNA nanotechnology. The database implements an upload interface, searching and database browsing. Each deposited nanostructures includes an image of the nanostructure, design file, an optional 3D view, and additional metadata such as experimental data, protocol or literature reference. The database accepts nanostructures in any preferred format used by the uploader for the nanostructure design. We further provide a set of conversion tools that encourage design file conversion into common formats (oxDNA and PDB) that can be used for setting up simulations, interactive editing or 3D visualization. The aim of the repository is to provide to the DNA/RNA nanotechnology community a resource for sharing their designs for further reuse in other systems and also to function as an archive of the designs that have been achieved in the field so far. Nanobase.org is available at https://nanobase.org/.

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