4.8 Article

Hymenoptera Genome Database: new genomes and annotation datasets for improved go enrichment and orthologue analyses

Journal

NUCLEIC ACIDS RESEARCH
Volume 50, Issue D1, Pages D1032-D1039

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkab1018

Keywords

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Funding

  1. United States Department of Agriculture National Institute of Food and Agriculture [2018-67013-27536, 1009273]
  2. NIFA [1009273, 913207] Funding Source: Federal RePORTER

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This article presents an update of the Hymenoptera Genome Database, with a significant increase in the number of species represented and enhancements to the Gene Ontology annotations and orthology datasets available. The database continues to provide genomic data mining capabilities and genome browsers for researchers in the field.
We report an update of the Hymenoptera Genome Database (HGD; http://HymenopteraGenome.org), a genomic database of hymenopteran insect species. The number of species represented in HGD has nearly tripled, with fifty-eight hymenopteran species, including twenty bees, twenty-three ants, eleven wasps and four sawflies. With a reorganized website, HGD continues to provide the HymenopteraMine genomic data mining warehouse and JBrowse/Apollo genome browsers integrated with BLAST. We have computed Gene Ontology (GO) annotations for all species, greatly enhancing the GO annotation data gathered from UniProt with more than a ten-fold increase in the number of GO-annotated genes. We have also generated orthology datasets that encompass all HGD species and provide orthologue clusters for fourteen taxonomic groups. The new GO annotation and orthology data are available for searching in HymenopteraMine, and as bulk file downloads.

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