4.4 Review

Mitochondrial iron metabolism and neurodegenerative diseases

Related references

Note: Only part of the references are listed.
Article Pediatrics

Association of Anemia with Neurodevelopmental Disorders in a Nationally Representative Sample of US Children

Wenhan Yang et al.

Summary: In a nationally representative sample of US children, significant associations were found between anemia and neurodevelopmental disorders including ASD, ADHD, and learning disability. Children with anemia were more likely to have neurodevelopmental disorders.

JOURNAL OF PEDIATRICS (2021)

Article Biochemistry & Molecular Biology

The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia

Piergiorgio La Rosa et al.

Summary: Ferroptosis is a form of iron-dependent cell death that may be involved in Friedreich's Ataxia. Nrf2 signaling plays a crucial role in ferroptosis, suggesting it as a potential target to combat neurodegenerative diseases.

REDOX BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation

Shannon Chiang et al.

Summary: This study investigated mitochondrial homeostasis in Friedreich's ataxia (FA) cardiomyopathy, revealing significant changes in key mitochondrial homeostatic mechanisms in the hearts of frataxin-deficient mice. The findings demonstrated dysfunction in mitochondrial proliferation, NAD+ metabolism, and mitochondrial dynamics, with an accumulation of Pink1/Parkin and increased autophagic/mitophagic flux. This mechanistic dissection offers insights into potential treatments targeting mitochondrial homeostasis and NAD+ metabolism in FA and other cardiodegenerative diseases.

REDOX BIOLOGY (2021)

Article Pharmacology & Pharmacy

Drp1-dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia

Joseph Johnson et al.

Summary: Friedreich ataxia is a neurodegenerative disease characterized by the lack of frataxin protein in mitochondria. Deficiency of frataxin leads to excessive mitochondrial fragmentation, partially dependent on Drp1 activity. Inhibiting Drp1 can reverse mitochondrial fragmentation.

PHARMACOLOGY RESEARCH & PERSPECTIVES (2021)

Article Multidisciplinary Sciences

Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5

Erdem M. Terzi et al.

Summary: Intracellular iron levels are strictly regulated to avoid iron-mediated ROS production. Loss of ISC synthesis can activate IRP2 independently of IRP1 and FBXL5, promoting ferroptosis sensitivity. Deletion of both IRP1 and IRP2 abolishes the iron-starvation response, preventing its activation by ISC synthesis inhibition.

SCIENCE ADVANCES (2021)

Article Biochemistry & Molecular Biology

FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster

Hui Wang et al.

MOLECULAR CELL (2020)

Review Multidisciplinary Sciences

Mitochondrial TCA cycle metabolites control physiology and disease

Inmaculada Martinez-Reyes et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice

Alexandra Seguin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Ferroptosis in Friedreich's Ataxia: A Metal-Induced Neurodegenerative Disease

Piergiorgio La Rosa et al.

BIOMOLECULES (2020)

Article Biochemistry & Molecular Biology

Defining the mechanism of the mitochondrial Atm1p [2Fe-2S] cluster exporter

Stephen A. Pearson et al.

METALLOMICS (2020)

Review Biochemistry & Molecular Biology

Transferrin and transferrin receptors update

Hiroshi Kawabata

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Biochemistry & Molecular Biology

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration

Shashank Masaldan et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Neurosciences

Nitric Oxide, Iron and Neurodegeneration

Chao Liu et al.

FRONTIERS IN NEUROSCIENCE (2019)

Review Neurosciences

Iron in Neurodegeneration - Cause or Consequence?

Alain Ndayisaba et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

Mechanism of frataxin bypass in human iron-sulfur cluster biosynthesis with implications for Friedreich's ataxia

Deepika Das et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Neurosciences

Iron, Myelin, and the Brain: Neuroimaging Meets Neurobiology

Harald E. Moeller et al.

TRENDS IN NEUROSCIENCES (2019)

Review Neurosciences

Aceruloplasminemia: A Severe Neurodegenerative Disorder Deserving an Early Diagnosis

Giacomo Marchi et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Biology

Brain iron transport

Zhong-Ming Qian et al.

BIOLOGICAL REVIEWS (2019)

Article Psychiatry

Association of Prenatal Maternal Anemia With Neurodevelopmental Disorders

Aline Marileen Wiegersma et al.

JAMA PSYCHIATRY (2019)

Article Medicine, Research & Experimental

Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling

Junghyung Park et al.

EXPERIMENTAL NEUROBIOLOGY (2019)

Article Oncology

Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis

Ling-Chu Chang et al.

CANCER LETTERS (2018)

Article Biochemistry & Molecular Biology

Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

Sonal Agrawal et al.

FREE RADICAL BIOLOGY AND MEDICINE (2018)

Review Biochemistry & Molecular Biology

Iron-sulfur clusters: from metals through mitochondria biogenesis to disease

Mauricio Cardenas-Rodriguez et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2018)

Review Medicine, Research & Experimental

Hepcidin, an emerging and important player in brain iron homeostasis

Driton Vela

JOURNAL OF TRANSLATIONAL MEDICINE (2018)

Review Clinical Neurology

Progress in the treatment of Friedreich ataxia

Geneieve Tai et al.

NEUROLOGIA I NEUROCHIRURGIA POLSKA (2018)

Article Biochemistry & Molecular Biology

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease

Li Niu et al.

CELL AND BIOSCIENCE (2018)

Article Neurosciences

Brain Iron Metabolism Dysfunction in Parkinson's Disease

Hong Jiang et al.

MOLECULAR NEUROBIOLOGY (2017)

Article Medicine, General & Internal

Aceruloplasminaemia: a disorder of diabetes and neurodegeneration

Genevieve L. Calder et al.

INTERNAL MEDICINE JOURNAL (2017)

Article Biochemistry & Molecular Biology

Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia

Sara Petrillo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Biochemistry & Molecular Biology

The transferrin receptor: the cellular iron gate

Elena Gammella et al.

METALLOMICS (2017)

Review Biology

Mitochondrial metabolites: undercover signalling molecules

Christian Frezza

INTERFACE FOCUS (2017)

Review Medical Laboratory Technology

Ferritin and iron studies in anaemia and chronic disease

Ying Y. Peng et al.

ANNALS OF CLINICAL BIOCHEMISTRY (2017)

Article Clinical Neurology

Quantitative Susceptibility Mapping Suggests Altered Brain Iron in Premanifest Huntington Disease

J. M. G. van Bergen et al.

AMERICAN JOURNAL OF NEURORADIOLOGY (2016)

Article Clinical Neurology

Iron accumulation in the basal ganglia in Huntington's disease: cross-sectional data from the IMAGE-HD study

Juan F. D. Dominguez et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2016)

Article Clinical Neurology

Compound Heterozygous FXN Mutations and Clinical Outcome in Friedreich Ataxia

Charles A. Galea et al.

ANNALS OF NEUROLOGY (2016)

Article Clinical Neurology

Iron and dopamine: a toxic couple

Dominic J. Hare et al.

BRAIN (2016)

Article Biochemistry & Molecular Biology

Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis?

Tim Hofer et al.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2016)

Review Neurosciences

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

A. M. Bertholet et al.

NEUROBIOLOGY OF DISEASE (2016)

Article Multidisciplinary Sciences

Imaging trace element distributions in single organelles and subcellular features

Yoav Kashiv et al.

SCIENTIFIC REPORTS (2016)

Review Genetics & Heredity

Neurodegeneration with Brain Iron Accumulation: Genetic Diversity and Pathophysiological Mechanisms

Esther Meyer et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 16 (2015)

Review Biochemistry & Molecular Biology

Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease

D. J. R. Lane et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)

Article Neurosciences

Expression and cellular localization of hepcidin mRNA and protein in normal rat brain

Ruma Raha-Chowdhury et al.

BMC NEUROSCIENCE (2015)

Article Medicine, General & Internal

Huntington disease

Gillian P. Bates et al.

NATURE REVIEWS DISEASE PRIMERS (2015)

Article Biochemistry & Molecular Biology

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

David Devos et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Review Biochemistry & Molecular Biology

Iron dysregulation in Huntington's disease

Michelle Muller et al.

JOURNAL OF NEUROCHEMISTRY (2014)

Review Biochemistry & Molecular Biology

Iron and mechanisms of emotional behavior

Jonghan Kim et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)

Review Clinical Neurology

The role of iron in brain ageing and neurodegenerative disorders

Roberta Ward et al.

LANCET NEUROLOGY (2014)

Article Cell Biology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli et al.

NATURE CELL BIOLOGY (2014)

Review Cell Biology

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

Antonio Ayala et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)

Article Clinical Neurology

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease

Scott Ayton et al.

ANNALS OF NEUROLOGY (2013)

Review Biochemistry & Molecular Biology

Metallostasis in Alzheimer's disease

Scott Ayton et al.

FREE RADICAL BIOLOGY AND MEDICINE (2013)

Article Biochemistry & Molecular Biology

Frataxin Deficiency Leads to Reduced Expression and Impaired Translocation of NF-E2-Related Factor (Nrf2) in Cultured Motor Neurons

Valentina D'Oria et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Biochemistry & Molecular Biology

Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

Chuang Guo et al.

NEUROCHEMISTRY INTERNATIONAL (2013)

Review Geriatrics & Gerontology

A delicate balance: Iron metabolism and diseases of the brain

Dominic Hare et al.

FRONTIERS IN AGING NEUROSCIENCE (2013)

Review Hematology

Role of hepcidin in the pathophysiology and diagnosis of anemia

Guido D'Angelo

BLOOD RESEARCH (2013)

Article Clinical Neurology

FXN methylation predicts expression and clinical outcome in Friedreich ataxia

Marguerite V. Evans-Galea et al.

ANNALS OF NEUROLOGY (2012)

Review Biochemistry & Molecular Biology

Functional roles of transferrin in the brain

Dominique F. Leitner et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)

Article Biochemistry & Molecular Biology

Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway

Francois Mouton-Liger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Article Biochemistry & Molecular Biology

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Peng Lei et al.

NATURE MEDICINE (2012)

Review Medicine, General & Internal

Iron Overload in Human Disease

Robert E. Fleming et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Multidisciplinary Sciences

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export

Yoshihiko Ichikawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biochemistry & Molecular Biology

Regulation of cellular iron metabolism

Jian Wang et al.

BIOCHEMICAL JOURNAL (2011)

Article Biochemistry & Molecular Biology

Glutathione: a key component of the cytoplasmic labile iron pool

Robert C. Hider et al.

BIOMETALS (2011)

Article Cell Biology

The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo

Toshiro Moroishi et al.

CELL METABOLISM (2011)

Article Neurosciences

H-ferritin is the Major Source of Iron for Oligodendrocytes

Bozho Todorich et al.

Review Clinical Neurology

Iron-dependent functions of mitochondria-relation to neurodegeneration

Gabriele Gille et al.

JOURNAL OF NEURAL TRANSMISSION (2011)

Review Clinical Neurology

Friedreich's ataxia: Pathology, pathogenesis, and molecular genetics

Arnulf H. Koeppen

JOURNAL OF THE NEUROLOGICAL SCIENCES (2011)

Editorial Material Biochemistry & Molecular Biology

Hugging tight in Huntington's

Ashu Johri et al.

NATURE MEDICINE (2011)

Article Neurosciences

DMT1 polymorphism and risk of Parkinson's disease

Qing He et al.

NEUROSCIENCE LETTERS (2011)

Article Biochemistry & Molecular Biology

Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin

Satoshi Kono et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)

Article Biochemistry & Molecular Biology

Iron in neuronal function and dysfunction

Gabriela A. Salvador

BIOFACTORS (2010)

Review Biochemistry & Molecular Biology

Does oxidative stress contribute to the pathology of Friedreich's ataxia? A radical question

Jeffrey S. Armstrong et al.

FASEB JOURNAL (2010)

Review Neurosciences

Mitochondrial Iron Metabolism and Its Role in Neurodegeneration

Maxx P. Horowitz et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Biochemistry & Molecular Biology

Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1

Hyun-Hee Cho et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Neurosciences

Oxidative stress and cell death in cells expressing L-ferritin variants

Anna Cozzi et al.

NEUROBIOLOGY OF DISEASE (2010)

Review Medicine, General & Internal

MECHANISMS OF DISEASE Alzheimer's Disease

Henry W. Querfurth et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Biochemistry & Molecular Biology

Electrostatics of the FeS clusters in respiratory complex I

Vernon A. Couch et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)

Article Biochemistry & Molecular Biology

Mitochondrial ABC proteins in health and disease

Ariane Zutz et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)

Article Clinical Neurology

Pathophysiology of Huntingtonʼs disease: from huntingtin functions to potential treatments

Emmanuel Roze et al.

CURRENT OPINION IN NEUROLOGY (2009)

Article Biochemistry & Molecular Biology

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene

Ana G. Barbeito et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Regulation of Mitochondrial Iron Import through Differential Turnover of Mitoferrin 1 and Mitoferrin 2

Prasad N. Paradkar et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Oxidative stress induces degradation of mitochondrial DNA

Inna Shokolenko et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant

Michael Li-Hsuan Huang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

Ajay A. Vashisht et al.

SCIENCE (2009)

Article Genetics & Heredity

Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance

Fanny Mochel et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2008)

Review Biochemistry & Molecular Biology

Maturation of iron-sulfur proteins in eukaryotes: Mechanisms, connected processes, and diseases

Roland Lill et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Iron deficiency alters dopamine uptake and response to L-DOPA injection in Sprague-Dawley rats

Laura E. Bianco et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Tim-2 is the receptor for H-ferritin on oligodendrocytes

Bozho Todorich et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Review Neurosciences

Mitochondrial fragmentation in neurodegeneration

Andrew B. Knott et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Article Multidisciplinary Sciences

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

Julio Salazar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Hematology

Mechanisms of iron loading and toxicity

Gregory J. Anderson

AMERICAN JOURNAL OF HEMATOLOGY (2007)

Article Biochemistry & Molecular Biology

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

Alain Martelli et al.

HUMAN MOLECULAR GENETICS (2007)

Article Biochemistry & Molecular Biology

Three histidine residues of amyloid-β peptide control the redox activity of copper and iron

M. Nakamura et al.

BIOCHEMISTRY (2007)

Article Genetics & Heredity

Frataxin gene point mutations in Italian Friedreich ataxia patients

Cinzia Gellera et al.

NEUROGENETICS (2007)

Review Biochemistry & Molecular Biology

Huntingtin-deficient zebrafish exhibit defects in iron utilization and development

Amanda L. Lumsden et al.

HUMAN MOLECULAR GENETICS (2007)

Article Medical Laboratory Technology

Analysis of ferritin genes in Parkinson disease

Barbara Foglieni et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2007)

Review Biochemistry & Molecular Biology

The machines that divide and fuse mitochondria

Suzanne Hoppins et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Huntingtin inclusion bodies are iron-dependent centers of oxidative events

Wance J. J. Firdaus et al.

FEBS JOURNAL (2006)

Review Multidisciplinary Sciences

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

Michael T. Lin et al.

NATURE (2006)

Review Biochemistry & Molecular Biology

Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes

Roland Lill et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)

Article Biochemistry & Molecular Biology

Regional and cellular gene expression changes in human Huntington's disease brain

A Hodges et al.

HUMAN MOLECULAR GENETICS (2006)

Article Multidisciplinary Sciences

Mitoferrin is essential for erythroid iron assimilation

GC Shaw et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant Huntingtin

T Milakovic et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model

T Nguyen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Neurosciences

Iron deficiency: Differential effects on monoamine transporters

MS Burhans et al.

NUTRITIONAL NEUROSCIENCE (2005)

Review Biochemistry & Molecular Biology

Structure, function, and formation of biological iron-sulfur clusters

DC Johnson et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2005)

Review Neurosciences

Iron, brain ageing and neurodegenerative disorders

L Zecca et al.

NATURE REVIEWS NEUROSCIENCE (2004)

Article Biochemistry & Molecular Biology

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

SY Jeong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells

GL Tan et al.

HUMAN MOLECULAR GENETICS (2003)

Article Neurosciences

Iron metabolism in mice with partial frataxin deficiency

MM Santos et al.

CEREBELLUM (2003)

Article Biochemistry & Molecular Biology

Mechanisms of copper incorporation into human ceruloplasmin

NE Hellman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript

JT Rogers et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Clinical Neurology

Weight loss in early stage of Huntington's disease

L Djoussé et al.

NEUROLOGY (2002)

Article Clinical Neurology

Association study between iron-related genes polymorphisms and Parkinson's disease

C Borie et al.

JOURNAL OF NEUROLOGY (2002)

Article Clinical Neurology

Microscopic R2*mapping of reduced brain iron in the belgrade rat

HA Zywicke et al.

ANNALS OF NEUROLOGY (2002)

Article Multidisciplinary Sciences

Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats

PB Walter et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Review Developmental Biology

Brain iron metabolism and neurodegenerative disorders

JC Sipe et al.

DEVELOPMENTAL NEUROSCIENCE (2002)

Review Biochemistry & Molecular Biology

Chemistry and biology of eukaryotic iron metabolism

P Aisen et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2001)

Article Cell Biology

Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells

E Smirnova et al.

MOLECULAR BIOLOGY OF THE CELL (2001)

Article Behavioral Sciences

Iron deficiency decreases dopamine D1 and D2 receptors in rat brain

KM Erikson et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2001)

Article Biochemistry & Molecular Biology

Redox-active iron mediates amyloid-β toxicity

CA Rottkamp et al.

FREE RADICAL BIOLOGY AND MEDICINE (2001)

Article Clinical Neurology

Early and progressive accumulation of reactive microglia in the Huntington disease brain

E Sapp et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)

Article Nutrition & Dietetics

Iron biology in immune function, muscle metabolism and neuronal functioning

JL Beard

JOURNAL OF NUTRITION (2001)

Article Clinical Neurology

Oxidative stress in patients with Friedreich ataxia

JB Schulz et al.

NEUROLOGY (2000)

Article Biochemistry & Molecular Biology

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

R Luthi-Carter et al.

HUMAN MOLECULAR GENETICS (2000)

Article Biochemistry & Molecular Biology

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

A Krause et al.

FEBS LETTERS (2000)