4.7 Article

Similar network compositions, but distinct neural dynamics underlying belief updating in environments with and without explicit outcomes

Journal

NEUROIMAGE
Volume 247, Issue -, Pages -

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2021.118821

Keywords

Confidence; Anterior hippocampus; Amygdala; Medial prefrontal cortex; Dynamic causal modeling

Funding

  1. University of Texas at Dallas
  2. Mental Illness Research, Education, and Clinical Center (MIRECC VISN 2) at the James J. Peter Veterans Affairs Medical Center, Bronx, NY
  3. National Institute on Drug Abuse [R01DA043695, R21DA049243]

Ask authors/readers for more resources

The neural dynamics underlying belief updating remain consistent across tasks, but the network dynamics change depending on the presence or absence of trial-by-trial value-based outcomes after each choice selection.
Classic decision theories typically assume the presence of explicit value-based outcomes after action selections to update beliefs about action-outcome contingencies. However, ecological environments are often opaque, and it remains unclear whether the neural dynamics underlying belief updating vary under conditions characterized by the presence or absence of such explicit value-based information, after each choice selection. We investigated this question in healthy humans ( n = 28) using Bayesian inference and two multi-option fMRI tasks: a multi-armed bandit task, and a probabilistic perceptual task, respectively with and without explicit value-based feedback after choice selections. Model-based fMRI analysis revealed a network encoding belief updating which did not change depending on the task. More precisely, we found a confidence-building network that included anterior hippocampus, amygdala, and medial prefrontal cortex (mPFC), which became more active as beliefs about action-outcome probabilities were confirmed by newly acquired information. Despite these consistent responses across tasks, dynamic causal modeling estimated that the network dynamics changed depending on the presence or absence of trial-by-trial value-based outcomes. In the task deprived of immediate feedback, the hippocampus increased its influence towards both amygdala and mPFC, in association with increased strength in the confidence signal. However, the opposite causal relations were found (i.e., from both mPFC and amygdala towards the hippocampus), in presence of immediate outcomes. This finding revealed an asymmetric relationship between decision confidence computations, which were based on similar computational models across tasks, and neural implementation, which varied depending on the availability of outcomes after choice selections.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available