4.6 Article

Deep learning for brain disorder diagnosis based on fMRI images

Journal

NEUROCOMPUTING
Volume 469, Issue -, Pages 332-345

Publisher

ELSEVIER
DOI: 10.1016/j.neucom.2020.05.113

Keywords

Artificial intelligence; Deep learning; Machine learning; Functional magnetic resonance imaging; Brain disorders; Diagnosis

Funding

  1. Natural Science and Engineering Research Council of Canada (NSERC)

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This article discusses the application of deep learning methods for brain disorder diagnosis based on fMRI images. Deep learning techniques have shown promise in better interpreting and processing fMRI data, and different deep learning models can be used for different fMRI tasks. The goal is to provide an overview of brain disorder diagnosis from the perspective of deep learning applications.
In modern neuroscience and clinical study, neuroscientists and clinicians often use non-invasive imaging techniques to validate theories and computational models, observe brain activities and diagnose brain disorders. The functional Magnetic Resonance Imaging (fMRI) is one of the commonly-used imaging modalities that can be used to understand human brain mechanisms as well as the diagnosis and treatment of brain disorders. The advances in artificial intelligence and the emergence of deep learning techniques have shown promising results to better interpret fMRI data. Deep learning techniques have rapidly become the state of the art for analyzing fMRI data sets and resulted in performance improvements in diverse fMRI applications. Deep learning is normally presented as an end-to-end learning process and can alleviate feature engineering requirements and hence reduce domain knowledge requirements to some extent. Under the framework of deep learning, fMRI data can be considered as images, time series or images series. Hence, different deep learning models such as convolutional neural networks, recurrent neural network, or a combination of both, can be developed to process fMRI data for different tasks. In this review, we discussed the basics of deep learning methods and focused on its successful implementations for brain disorder diagnosis based on fMRI images. The goal is to provide a high-level overview of brain disorder diagnosis with fMRI images from the perspective of deep learning applications. (c) 2020 Elsevier B.V. All rights reserved.

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