Related references
Note: Only part of the references are listed.Microtubule dynamics in healthy and injured neurons
Melissa M. Rolls et al.
DEVELOPMENTAL NEUROBIOLOGY (2021)
The cytoskeleton as a modulator of tension driven axon elongation
Sara C. Sousa et al.
DEVELOPMENTAL NEUROBIOLOGY (2021)
Role of glia in optic nerve
Meysam Yazdankhah et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2021)
Age-related loss of axonal regeneration is reflected by the level of local translation
Susan van Erp et al.
EXPERIMENTAL NEUROLOGY (2021)
Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice
Marco Leibinger et al.
NATURE COMMUNICATIONS (2021)
Posttranslational Modification of Sox11 Regulates RGC Survival and Axon Regeneration
Kun-Che Chang et al.
ENEURO (2021)
Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers
Eitan Erez Zahavi et al.
DEVELOPMENTAL CELL (2021)
Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury
Veselina Petrova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Actin dynamics in the growth cone: a key player in axon regeneration
Sergio Carvalho Leite et al.
CURRENT OPINION IN NEUROBIOLOGY (2021)
Neuro-protection and neuro-regeneration of the optic nerve: recent advances and future directions
Kimberly K. Gokoffski et al.
CURRENT OPINION IN NEUROLOGY (2020)
Spatiotemporal distribution of chondroitin sulfate proteoglycans after optic nerve injury in rodents
Craig S. Pearson et al.
EXPERIMENTAL EYE RESEARCH (2020)
Immune cell regulation of glia during CNS injury and disease
Andrew D. Greenhalgh et al.
NATURE REVIEWS NEUROSCIENCE (2020)
Microglia Mediated Neuroinflammation: Focus on PI3K Modulation
Antonia Cianciulli et al.
BIOMOLECULES (2020)
Glial Cells: Role of the Immune Response in Ischemic Stroke
Shenbin Xu et al.
FRONTIERS IN IMMUNOLOGY (2020)
Injured adult neurons regress to an embryonic transcriptional growth state
Gunnar H. D. Poplawski et al.
NATURE (2020)
Reactive Astrocytes Display Pro-inflammatory Adaptability with Modulation of Notch-PI3K-AKT Signaling Pathway Under Inflammatory Stimulation
Ying-Ying Cheng et al.
NEUROSCIENCE (2020)
PI3-kinase delta enhances axonalPIP3to support axon regeneration in the adultCNS
Bart Nieuwenhuis et al.
EMBO MOLECULAR MEDICINE (2020)
The protein kinase Akt acts as a coat adaptor in endocytic recycling
Jia-Wei Hsu et al.
NATURE CELL BIOLOGY (2020)
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
William Renthal et al.
NEURON (2020)
Protective Functions of Reactive Astrocytes Following Central Nervous System Insult
Mathias Linnerbauer et al.
FRONTIERS IN IMMUNOLOGY (2020)
Axon Regeneration in the Mammalian Optic Nerve
Philip R. Williams et al.
ANNUAL REVIEW OF VISION SCIENCE, VOL 6, 2020 (2020)
Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury
Di Wu et al.
NATURE COMMUNICATIONS (2020)
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS
Veselina Petrova et al.
NATURE COMMUNICATIONS (2020)
Harnessing PTEN's Growth Potential in Neuronal Development and Disease
Joachim Fuchs et al.
NEUROSCIENCE INSIGHTS (2020)
Bisperoxovanadium Mediates Neuronal Protection through Inhibition of PTEN and Activation of PI3K/AKT-mTOR Signaling after Traumatic Spinal Injuries
Chandler L. Walker et al.
JOURNAL OF NEUROTRAUMA (2019)
Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis
Kazuma Sakamoto et al.
NATURE CHEMICAL BIOLOGY (2019)
PI3K isoforms in cell signalling and vesicle trafficking
Benoit Bilanges et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Emerging role of PI3K/AKT in tumor-related epigenetic regulation
Qi Yang et al.
SEMINARS IN CANCER BIOLOGY (2019)
p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model
Ramon Martinez-Marmol et al.
JOURNAL OF NEUROSCIENCE (2019)
ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS
Andrea Tedeschi et al.
NEURON (2019)
Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons
Ilaria Palmisano et al.
NATURE NEUROSCIENCE (2019)
The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches
Annika Brosig et al.
CELL REPORTS (2019)
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex
Alexandros Poulopoulos et al.
NATURE (2019)
GSK3-CRMP2 signaling mediates axonal regeneration induced by Pten knockout
Marco Leibinger et al.
COMMUNICATIONS BIOLOGY (2019)
Integrins promote axonal regeneration after injury of the nervous system
Bart Nieuwenhuis et al.
BIOLOGICAL REVIEWS (2018)
Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury
Emily R. Burnside et al.
BRAIN (2018)
Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury
Faith H. Brennan et al.
CURRENT OPINION IN NEUROLOGY (2018)
Neuronal Intrinsic Regenerative Capacity: The Impact of Microtubule Organization and Axonal Transport
Blanca Murillo et al.
DEVELOPMENTAL NEUROBIOLOGY (2018)
The Virtuous Cycle of Axon Growth: Axonal Transport of Growth-Promoting Machinery as an Intrinsic Determinant of Axon Regeneration
Veselina Petrova et al.
DEVELOPMENTAL NEUROBIOLOGY (2018)
Signaling Pathways Involved in the Regulation of mRNA Translation
Philippe P. Roux et al.
MOLECULAR AND CELLULAR BIOLOGY (2018)
Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
Arnau Hervera et al.
NATURE CELL BIOLOGY (2018)
The functions and regulation of the PTEN tumour suppressor: new modes and prospects
Yu-Ru Lee et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Intrinsic mechanisms of neuronal axon regeneration
Marcus Mahar et al.
NATURE REVIEWS NEUROSCIENCE (2018)
Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System
Yi-Lan Weng et al.
NEURON (2018)
Advances and Limitations of Current Epigenetic Studies Investigating Mammalian Axonal Regeneration
Ilaria Palmisano et al.
NEUROTHERAPEUTICS (2018)
PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules
Christina Kath et al.
PLOS ONE (2018)
Locally translated mTOR controls axonal local translation in nerve injury
Marco Terenzio et al.
SCIENCE (2018)
Axon Regeneration in the Central Nervous System: Facing the Challenges from the Inside
Michele Curcio et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)
Required growth facilitators propel axon regeneration across complete spinal cord injury
Mark A. Anderson et al.
NATURE (2018)
Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor/tropomyosin- related kinase receptor-B signaling
Andrew Osborne et al.
CELL DEATH & DISEASE (2018)
Coordination of Necessary and Permissive Signals by PTEN Inhibition for CNS Axon Regeneration
Jie Zhang et al.
FRONTIERS IN NEUROSCIENCE (2018)
Epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration
Young Mi Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury
Hassan Al-Ali et al.
JOURNAL OF NEUROSCIENCE (2017)
PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
Mouhannad Malek et al.
MOLECULAR CELL (2017)
Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others
Michael W. Norsworthy et al.
NEURON (2017)
An Intrinsic Epigenetic Barrier for Functional Axon Regeneration
Yi-Lan Weng et al.
NEURON (2017)
A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions
Yuanyuan Liu et al.
NEURON (2017)
Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity
Marco Leibinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Selective rab11 transport and the intrinsic regenerative ability of CNS axons
Hiroaki Koseki et al.
ELIFE (2017)
The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer
Jennifer M. Spangle et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2017)
The PI3K Pathway in Human Disease
David A. Fruman et al.
CELL (2017)
Bisperoxovandium (pyridin-2-squaramide) targets both PTEN and ERK1/2 to confer neuroprotection
Zhi-Feng Zhang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
AKT/PKB Signaling: Navigating the Network
Brendan D. Manning et al.
CELL (2017)
Promotion of Functional Nerve Regeneration by Inhibition of Microtubule Detyrosination
Philipp Gobrecht et al.
JOURNAL OF NEUROSCIENCE (2016)
Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord
Menghon Cheah et al.
JOURNAL OF NEUROSCIENCE (2016)
Boosting Central Nervous System Axon Regeneration by Circumventing Limitations of Natural Cytokine Signaling
Marco Leibinger et al.
MOLECULAR THERAPY (2016)
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program
Vijayendran Chandran et al.
NEURON (2016)
Evidence for an Age-Dependent Decline in Axon Regeneration in the Adult Mammalian Central Nervous System
Cedric G. Geoffroy et al.
CELL REPORTS (2016)
Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent
Melissa R. Andrews et al.
ENEURO (2016)
PI3K signalling in inflammation
P. T. Hawkins et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)
Conditional genetic deletion of PTEN after a spinal cord injury enhances regenerative growth of CST axons and motor function recovery in mice
Camelia A. Danilov et al.
EXPERIMENTAL NEUROLOGY (2015)
Viral vector-based improvement of optic nerve regeneration: characterization of individual axons' growth patterns and synaptogenesis in a visual target
B. J. Yungher et al.
GENE THERAPY (2015)
Pten Deletion Promotes Regrowth of Corticospinal Tract Axons 1 Year after Spinal Cord Injury
Kaimeng Du et al.
JOURNAL OF NEUROSCIENCE (2015)
Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice
Cedric G. Geoffroy et al.
JOURNAL OF NEUROSCIENCE (2015)
Exclusion of Integrins from CNS Axons Is Regulated by Arf6 Activation and the AIS
Elske H. P. Franssen et al.
JOURNAL OF NEUROSCIENCE (2015)
Subtype-Specific Regeneration of Retinal Ganglion Cells following Axotomy: Effects of Osteopontin and mTOR Signaling
Xin Duan et al.
NEURON (2015)
Systemic administration of epothilone B promotes axon regeneration after spinal cord injury
Joerg Ruschel et al.
SCIENCE (2015)
Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase
Lizhen Chen et al.
ELIFE (2015)
Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia
Jerry Silver et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
The effect of systemic PTEN antagonist peptides on axon growth and functional recovery after spinal cord injury
Yosuke Ohtake et al.
BIOMATERIALS (2014)
Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2
Marcia A. Liz et al.
BMC BIOLOGY (2014)
Myelin-associated inhibitors in axonal growth after CNS injury
Cedric G. Geoffroy et al.
CURRENT OPINION IN NEUROBIOLOGY (2014)
Activation of PI3K and R-Ras Signaling Promotes the Extension of Sensory Axons on Inhibitory Chondroitin Sulfate Proteoglycans
Lee Silver et al.
DEVELOPMENTAL NEUROBIOLOGY (2014)
PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury
Chandler L. Walker et al.
NEUROSCIENCE LETTERS (2014)
PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model
Pei Ching Low et al.
NATURE COMMUNICATIONS (2014)
Activation of diverse signalling pathways by oncogenic PIK3CA mutations
Xinyan Wu et al.
NATURE COMMUNICATIONS (2014)
The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration
Liu Yang et al.
NATURE COMMUNICATIONS (2014)
Sustained GSK3 activity markedly facilitates nerve regeneration
Philipp Gobrecht et al.
NATURE COMMUNICATIONS (2014)
GnRH Neuronal Migration and Olfactory Bulb Neurite Outgrowth Are Dependent on FGF Receptor 1 Signaling, Specifically via the PI3K p110α Isoform in Chick Embryo
Youli Hu et al.
ENDOCRINOLOGY (2013)
Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance
Steven J. Henle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Short Hairpin RNA against PTEN Enhances Regenerative Growth of Corticospinal Tract Axons after Spinal Cord Injury
Katherine Zukor et al.
JOURNAL OF NEUROSCIENCE (2013)
Motor Axon Regeneration and Muscle Reinnervation in Young Adult and Aged Animals
Hyuno Kang et al.
JOURNAL OF NEUROSCIENCE (2013)
BDNF Regulates Rab11-Mediated Recycling Endosome Dynamics to Induce Dendritic Branching
Oscar M. Lazo et al.
JOURNAL OF NEUROSCIENCE (2013)
DELAYED ADMINISTRATION OF A PTEN INHIBITOR BPV IMPROVES FUNCTIONAL RECOVERY AFTER EXPERIMENTAL STROKE
L. Mao et al.
NEUROSCIENCE (2013)
Optogenetic Control of PIP3: PIP3 Is Sufficient to Induce the Actin-Based Active Part of Growth Cones and Is Regulated via Endocytosis
Toshiyuki Kakumoto et al.
PLOS ONE (2013)
PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1
Saijilafu et al.
NATURE COMMUNICATIONS (2013)
Phosphoinositides Differentially Regulate Protrudin Localization through the FYVE Domain
Jung-Eun Gil et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons
Richard Eva et al.
JOURNAL OF NEUROSCIENCE (2012)
PI3K signalling: the path to discovery and understanding
Bart Vanhaesebroeck et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Assembly of a new growth cone after axotomy: the precursor to axon regeneration
Frank Bradke et al.
NATURE REVIEWS NEUROSCIENCE (2012)
Systemic Bisperoxovanadium Activates Akt/mTOR, Reduces Autophagy, and Enhances Recovery following Cervical Spinal Cord Injury
Chandler L. Walker et al.
PLOS ONE (2012)
Promoting optic nerve regeneration
Dietmar Fischer et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2012)
Asymmetric PI(3,4,5)P3 and Akt Signaling Mediates Chemotaxis of Axonal Growth Cones
Steven J. Henle et al.
JOURNAL OF NEUROSCIENCE (2011)
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3
Fang Sun et al.
NATURE (2011)
Self-amplifying autocrine actions of BDNF in axon development
Pei-Lin Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury
Farida Hellal et al.
SCIENCE (2011)
Phosphatidylinositol 3-Kinase Facilitates Microtubule-dependent Membrane Transport for Neuronal Growth Cone Guidance
Hiroki Akiyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord
Alex J. T. Hyatt et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Rab11 and Its Effector Rab Coupling Protein Contribute to the Trafficking of β1 Integrins during Axon Growth in Adult Dorsal Root Ganglion Neurons and PC12 Cells
Richard Eva et al.
JOURNAL OF NEUROSCIENCE (2010)
PTEN deletion enhances the regenerative ability of adult corticospinal neurons
Kai Liu et al.
NATURE NEUROSCIENCE (2010)
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2
Gerald R. V. Hammond et al.
BIOCHEMICAL JOURNAL (2009)
IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury
Edmund R. Hollis et al.
EXPERIMENTAL NEUROLOGY (2009)
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
Matthew Oser et al.
JOURNAL OF CELL BIOLOGY (2009)
Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation
Edmund R. Hollis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
KLF Family Members Regulate Intrinsic Axon Regeneration Ability
Darcie L. Moore et al.
SCIENCE (2009)
The pleckstrin homology domain of the Arf6-specific exchange factor EFA6 localizes to the plasma membrane by interacting with phosphatidylinositol 4,5-bisphosphate and F-actin
Eric Macia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2
Jin Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments
Patrick T. Caswell et al.
JOURNAL OF CELL BIOLOGY (2008)
Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
Kevin Kyungsuk Park et al.
SCIENCE (2008)
Control of Axonal Growth and Regeneration of Sensory Neurons by the p110δ PI 3-Kinase
Britta J. Eickholt et al.
PLOS ONE (2007)
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
Frederic Tremblay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis
K. E. Cosker et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Control of cell polarity and motility by the PtdIns(3,4,5)P-3 phosphatase SHIP1
Miki Nishio et al.
NATURE CELL BIOLOGY (2007)
PCAF modulates PTEN activity
Koichi Okumura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
IGF-1 receptor is essential for the establishment of hippocampal neuronal polarity
Lucas Sosa et al.
NATURE NEUROSCIENCE (2006)
Oncogenic transformation induced by the p110β, -γ, and -δ isoforms of class I phosphoinositide 3-kinase
S Kang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin β1 to control cell migration
J Li et al.
DEVELOPMENTAL CELL (2005)
Involvement of a Rac activator, P-Rex1, in neurotrophin-derived signaling and neuronal migration
M Yoshizawa et al.
JOURNAL OF NEUROSCIENCE (2005)
The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK
S Chierzi et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity
T Yoshimura et al.
CELL (2005)
PIP3 is involved in neuronal polarization and axon formation
C Ménager et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Characterisation of the Rab binding properties of Rab coupling protein (RCP) by site-directed mutagenesis
AJ Lindsay et al.
FEBS LETTERS (2004)
Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo
Y Gao et al.
NEURON (2004)
NGF-induced axon growth is mediated by localized inactivation of GSK-30 and functions of the microtubule plus end binding protein APC
FQ Zhou et al.
NEURON (2004)
P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac
HCE Welch et al.
CELL (2002)
Cytohesins and centaurins: mediators of PI 3-kinase regulated Arf signaling
PA Randazzo et al.
TRENDS IN BIOCHEMICAL SCIENCES (2001)