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Article
Biochemistry & Molecular Biology
Adipocyte-derived exosomes may promote breast cancer progression in type 2 diabetes
Naser Jafari et al.
Summary: The study found that vesicles shed by adipocytes from type 2 diabetes patients or insulin-resistant individuals contain protein TSP5 that promotes EMT in breast cancer cells, potentially worsening the prognosis for breast cancer patients. Additionally, the gene expression in these vesicles can affect the prognosis of breast cancer patients.
SCIENCE SIGNALING (2021)