4.8 Review

The emergence, genomic diversity and global spread of SARS-CoV-2

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Spike mutation D614G alters SARS-CoV-2 fitness

Jessica A. Plante et al.

Summary: The D614G substitution in the SARS-CoV-2 spike protein enhances viral replication and infectivity in human lung epithelial cells, primary airway tissues, and hamsters. This variant may increase transmission in the upper respiratory tract and doesn't seem to significantly reduce vaccine efficacy. Further research on therapeutic antibodies targeting the circulating G614 virus is recommended.

NATURE (2021)

Article Biochemistry & Molecular Biology

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Erik Volz et al.

Summary: The study suggests a positive selection for the SARS-CoV-2 spike protein variant D614G in the UK, but no evidence of differences in COVID-19 mortality or clinical severity in patients infected with this variant. 614G is associated with higher viral load and younger age of patients compared to 614D.
Article Microbiology

Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

Allison J. Greaney et al.

Summary: Antibodies targeting the SARS-CoV-2 spike receptor-binding domain (RBD) are key in neutralizing antibody responses, and a deep mutational scanning method was used to assess the impact of all amino-acid mutations in the RBD on antibody binding with 10 human monoclonal antibodies. The study identified the clustered escape mutations in different surfaces of the RBD that correspond to structurally defined antibody epitopes, showing that even antibodies targeting the same surface can have distinct escape mutations.

CELL HOST & MICROBE (2021)

Article Multidisciplinary Sciences

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

Bryan A. Johnson et al.

Summary: The genetic mutation in SARS-CoV-2 resulted in better fitness in some cells but lower replication capacity in human respiratory cell lines. Despite reducing disease symptoms, the Delta PRRA mutant provided protection against rechallenge with the wildtype SARS-CoV-2.

NATURE (2021)

News Item Multidisciplinary Sciences

Viral evolution may herald new pandemic phase

Kai Kupferschmidt

SCIENCE (2021)

Article Multidisciplinary Sciences

Inferring the effectiveness of government interventions against COVID-19

Jan M. Brauner et al.

Summary: Research has found that closing educational institutions, limiting gathering sizes, and closing face-to-face businesses are effective nonpharmaceutical interventions in controlling the COVID-19 pandemic, while the additional effect of stay-at-home orders is relatively small.

SCIENCE (2021)

Article Multidisciplinary Sciences

Establishment and lineage dynamics of the SARS-CoV-2 epidemic in the UK

Louis du Plessis et al.

Summary: The study analyzed the genetic lineage structure of the early UK COVID-19 epidemic through genomic sampling, identifying that virus lineages introduced before the national lockdown tended to be larger and more dispersed. After the lockdown, lineage importation and regional diversity decreased, while lineage elimination depended on lineage size. The research emphasizes the impact of genetic perspective on transmission dynamics for COVID-19 epidemiology and control.

SCIENCE (2021)

Article Public, Environmental & Occupational Health

Effect of internationally imported cases on internal spread of COVID-19: a mathematical modelling study

Timothy W. Russell et al.

Summary: The study found that in some countries, imported cases may have little impact on local COVID-19 epidemics, while in others, they may contribute a higher proportion to the total incidence. Stringent travel restrictions may help control the epidemic in some countries, but have limited impact on others.

LANCET PUBLIC HEALTH (2021)

Article Biochemistry & Molecular Biology

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

Wilfredo F. Garcia-Beltran et al.

Summary: New variants of SARS-CoV-2 show high resistance to vaccine neutralization, with some able to escape vaccine responses with just a few mutations, highlighting the importance of developing broadly protective measures against variants.
Article Microbiology

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

Allison J. Greaney et al.

Summary: The evolution of SARS-CoV-2 may impact the recognition of the virus by human antibody-mediated immunity, with mutations affecting antibody binding varying significantly among individuals and within the same individual over time. Despite this variability, mutations that greatly reduce antibody binding usually occur at specific sites in the RBD, with E484 being the most crucial. These findings can inform surveillance efforts for SARS-CoV-2 evolution in the future.

CELL HOST & MICROBE (2021)

Article Multidisciplinary Sciences

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier et al.

Summary: The B.1.1.7 variant of SARS-CoV-2 exhibited reduced neutralization by vaccines and antibodies from recovered COVID-19 patients, with a more substantial loss seen when introducing the E484K mutation. This mutation poses a threat to the efficacy of the BNT162b2 vaccine.

NATURE (2021)

News Item Multidisciplinary Sciences

The coronavirus is here to stay - here's what that means

Nicky Phillips

Summary: Scientists expect the virus that causes COVID-19 to become endemic and pose less danger over time, according to a Nature survey.

NATURE (2021)

Article Multidisciplinary Sciences

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

Pengfei Wang et al.

Summary: The COVID-19 pandemic has had global repercussions, with promising vaccines and monoclonal antibody therapies. However, newly detected variants of SARS-CoV-2 present challenges to these treatment options.

NATURE (2021)

Article Multidisciplinary Sciences

SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp et al.

Summary: Chronic infection with SARS-CoV-2 can lead to viral evolution and increased resistance to neutralizing antibodies in immunosuppressed individuals treated with convalescent plasma. During convalescent plasma therapy, there were significant shifts in the viral population structure and sensitivity, suggesting strong selection pressure on the virus during treatment.

NATURE (2021)

Article Biochemistry & Molecular Biology

Variation in SARS-CoV-2 outbreaks across sub-Saharan Africa

Benjamin L. Rice et al.

Summary: The SARS-CoV-2 pandemic has shown low burdens in sub-Saharan Africa compared to other regions, potentially influenced by factors such as climate and population demographics. Caution is needed when interpreting analyses that aggregate data from low- and middle-income settings. Heterogeneity in connectivity across sub-Saharan Africa may contribute to variance in the pace of viral spread.

NATURE MEDICINE (2021)

Article Biochemistry & Molecular Biology

SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

Constantinos Kurt Wibmer et al.

Summary: The SARS-CoV-2 virus in the B.1.351 variant discovered in South Africa can evade neutralization by most antibodies when expressed, but does not affect binding by convalescent plasma. This suggests the potential for reinfection with antigenically distinct variants and predicts reduced efficacy of spike-based vaccines.

NATURE MEDICINE (2021)

Article Multidisciplinary Sciences

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

Nicholas G. Davies et al.

Summary: A new variant of SARS-CoV-2 has emerged in England, with a higher reproduction number and potential for large resurgences of COVID-19 cases. Without stringent control measures, it is projected that COVID-19 hospitalizations and deaths in England for the first 6 months of 2021 will exceed those in 2020. The variant has spread globally and exhibited similar transmission increases in Denmark, Switzerland, and the United States.

SCIENCE (2021)

Article Multidisciplinary Sciences

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

Chadi M. Saad-Roy et al.

Summary: Given vaccine dose shortages and logistical challenges, various deployment strategies are being proposed to increase population immunity levels to SARS-CoV-2. While focusing on one dose may decrease infections in the short term, the long-term outcomes depend on the relative immune robustness of this approach. Under conditions of partial population immunity, a one-dose policy may increase the potential for antigenic evolution.

SCIENCE (2021)

Article Multidisciplinary Sciences

Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia

Supaporn Wacharapluesadee et al.

Summary: A study identified a SARS-CoV-2-related coronavirus (SC2r-CoV), RacCS203, in Rhinolophus acuminatus bats from Thailand, with 91.5% genome similarity to SARS-CoV-2, and demonstrated that sera obtained from bats and Malayan pangolin can neutralize SARS-CoV-2.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

Oscar A. MacLean et al.

Summary: The study suggests that SARS-CoV-2 has undergone limited significant adaptation to humans, with evidence of moderate positive selection concentrated in the early phases of the pandemic. In contrast, bat Sarbecoviruses show evidence of significant positive selection and an adaptive depletion in CpG composition. This indicates that the progenitor of SARS-CoV-2 likely acquired efficient human-human transmission capabilities through evolutionary history in bats, leading to the emergence of a relatively generalist virus.

PLOS BIOLOGY (2021)

Article Multidisciplinary Sciences

A novel SARS-CoV-2 related coronavirus in bats from Cambodia

Deborah Delaune et al.

Summary: The study identified SARS-CoV-2 related coronaviruses in bats sampled in Cambodia, indicating a wider geographic distribution than previously reported. The findings suggest that Southeast Asia may be a key area to consider for future coronavirus surveillance.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Antibody evasion by the P.1 strain of SARS-CoV-2

Wanwisa Dejnirattisai et al.

Summary: Ending the SARS-CoV-2 pandemic requires global vaccination. New virus strains with mutations impact antibody responses, but some variants are less resistant than others. A monoclonal antibody can neutralize different variants and partially restore neutralization potency for other public antibodies.
Editorial Material Medicine, General & Internal

The Potential Future of the COVID-19 Pandemic Will SARS-CoV-2 Become a Recurrent Seasonal Infection?

Christopher J. L. Murray et al.

Summary: The viewpoint discusses the possibility of COVID-19 becoming a seasonal disease like influenza and suggests strategies to mitigate the consequences for communities and health systems, including changes in surveillance methods, medical and public health responses, and socioeconomic programs.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Article Infectious Diseases

Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study

Dan Frampton et al.

Summary: This study describes the emergence of the B.1.1.7 variant of concern, its virological characteristics, and clinical severity in patients. Increased viral load was found in B.1.1.7 infection, but no association with severe disease was identified in the hospitalized cohort.

LANCET INFECTIOUS DISEASES (2021)

Article Multidisciplinary Sciences

Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7

Nicholas G. Davies et al.

Summary: Studies have shown that the SARS-CoV-2 B.1.1.7 lineage is more transmissible and may cause more severe illness compared to pre-existing variants.

NATURE (2021)

Article Multidisciplinary Sciences

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

Erik Volz et al.

Summary: Genetic and testing data from England indicate that the SARS-CoV-2 variant B.1.1.7 has a transmission advantage over other lineages, showing a rapid expansion during autumn 2020. Analysis of S gene target failures (SGTF) in community-based diagnostic PCR testing suggests that B.1.1.7 is more transmissible than non-variant of concern lineages and has a significant transmission advantage, with a reproduction number 50% to 100% higher. Additionally, cases of B.1.1.7 appear to include a larger share of under 20-year-olds compared to non-variant cases.

NATURE (2021)

Letter Multidisciplinary Sciences

Partial immunity and SARS-CoV-2 mutations

William P. Hanage et al.

SCIENCE (2021)

Article Public, Environmental & Occupational Health

Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study

Mark S. Graham et al.

Summary: The study showed that the B.1.1.7 variant did not result in changes in COVID-19 symptoms or duration of illness, and there was no significant increase in reinfection rate compared to previous variants.

LANCET PUBLIC HEALTH (2021)

Article Biochemistry & Molecular Biology

Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses

Hong Zhou et al.

Summary: A study in Yunnan province, China, found the existence of bat coronaviruses related to both SARS-CoV-2 and SARS-CoV, with RpYN06 virus being the closest relative of SARS-CoV-2. Ecological modeling predicted the co-existence of up to 23 Rhinolophus bat species, with the largest hot-spots extending from South Laos and Vietnam to southern China. The study highlights the remarkable diversity of bat coronaviruses at the local scale.
Article Biochemistry & Molecular Biology

Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum

Chang Liu et al.

Summary: Recent study examined the neutralizing ability of monoclonal antibodies, convalescent and vaccine sera against the Indian variants B.1.617.1 and B.1.617.2, showing that the neutralization of these variants is reduced compared to the ancestral strains, without widespread antibody escape as seen in other variants like B.1.351.
Review Biochemistry & Molecular Biology

The origins of SARS-CoV-2: A critical review

Edward C. Holmes et al.

Summary: This article critically reviews the current scientific evidence to help clarify the origin of SARS-CoV-2. Recent debate has centered around two competing ideas: a laboratory escape scenario and zoonotic emergence.
Article Multidisciplinary Sciences

Untangling introductions and persistence in COVID-19 resurgence in Europe

Philippe Lemey et al.

Summary: In late summer 2020, more than half of the SARS-CoV-2 lineages circulating in many European countries resulted from new introductions, and the success in onward transmission of these newly introduced lineages was negatively associated with the local incidence of COVID-19. The widespread dissemination of variants in summer 2020 highlights the threat of viral spread when restrictions are lifted.

NATURE (2021)

Article Multidisciplinary Sciences

BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants

Jianying Liu et al.

Summary: Serum samples from individuals vaccinated with the BNT162b2 vaccine can neutralize various SARS-CoV-2 variants, indicating mass immunization as a central strategy to end the global COVID-19 pandemic.

NATURE (2021)

Review Microbiology

SARS-CoV-2 variants, spike mutations and immune escape

William T. Harvey et al.

Summary: The evolution of SARS-CoV-2 has been characterized by the emergence of mutations and variants that impact virus characteristics. Manufacturers are preparing for possible updates to vaccines in response to changes in the virus population, and it is crucial to monitor genetic and antigenic changes alongside experiments to understand the impacts of mutations.

NATURE REVIEWS MICROBIOLOGY (2021)

News Item Multidisciplinary Sciences

Delta variant triggers new phase in the pandemic

Kai Kupferschmidt et al.

SCIENCE (2021)

Article Immunology

Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination

Sarah Cobey et al.

Summary: When vaccines are in limited supply, expanding the number of people who receive the vaccine by dose-sparing strategies may reduce disease and mortality, although it could potentially increase the risk of vaccine-escape variants. Preliminary evidence suggests that such strategies could slow the rate of viral escape, as long as vaccination provides some protection against escape variants.

NATURE REVIEWS IMMUNOLOGY (2021)

Article Health Care Sciences & Services

Antibody seroprevalence in the epicenter Wuhan, Hubei, and six selected provinces after containment of the first epidemic wave of COVID-19 in China

Zhongjie Li et al.

Summary: China successfully contained the first wave of the COVID-19 epidemic, as evidenced by low overall infection rates and predominantly asymptomatic cases of SARS-CoV-2 infection revealed in serological surveys.

LANCET REGIONAL HEALTH-WESTERN PACIFIC (2021)

Article Infectious Diseases

Novel coronavirus (2019-nCoV) early-stage importation risk to Europe, January 2020

Giulia Pullano et al.

EUROSURVEILLANCE (2020)

Editorial Material Public, Environmental & Occupational Health

Potential for global spread of a novel coronavirus from China

Isaac I. Bogoch et al.

JOURNAL OF TRAVEL MEDICINE (2020)

Article Multidisciplinary Sciences

A new coronavirus associated with human respiratory disease in China

Fan Wu et al.

NATURE (2020)

Article Multidisciplinary Sciences

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou et al.

NATURE (2020)

Article Medicine, General & Internal

First Case of 2019 Novel Coronavirus in the United States

Michelle L. Holshue et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

A Novel Coronavirus from Patients with Pneumonia in China, 2019

Na Zhu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia

Qun Li et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Multidisciplinary Sciences

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

Qihui Wang et al.

Article Biochemistry & Molecular Biology

Genomic Epidemiology of SARS-CoV-2 in Guangdong Province, China

Jing Lu et al.

Article Biochemistry & Molecular Biology

Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States

Joseph R. Fauver et al.

Article Medicine, General & Internal

Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China

An Pan et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Multidisciplinary Sciences

Impact of international travel and border control measures on the global spread of the novel 2019 coronavirus outbreak

Chad R. Wells et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Susceptible supply limits the role of climate in the early SARS-CoV-2 pandemic

Rachel E. Baker et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Estimating the burden of SARS-CoV-2 in France

Henrik Salje et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

The effect of human mobility and control measures on the COVID-19 epidemic in China

Moritz U. G. Kraemer et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Introductions and early spread of SARS-CoV-2 in the New York City area

Ana S. Gonzalez-Reiche et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2

Salvatore Di Giorgio et al.

SCIENCE ADVANCES (2020)

Article Multidisciplinary Sciences

Effect of non-pharmaceutical interventions to contain COVID-19 in China

Shengjie Lai et al.

NATURE (2020)

Article Multidisciplinary Sciences

Population flow drives spatio-temporal distribution of COVID-19 in China

Jayson S. Jia et al.

NATURE (2020)

Article Multidisciplinary Sciences

Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins

Kangpeng Xiao et al.

NATURE (2020)

Article Multidisciplinary Sciences

Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins

Tommy Tsan-Yuk Lam et al.

NATURE (2020)

Letter Biochemistry & Molecular Biology

The proximal origin of SARS-CoV-2

Kristian G. Andersen et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy

Giulia Giordano et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

Qianqian Li et al.

Article Public, Environmental & Occupational Health

A vulnerability index for the management of and response to the COVID-19 epidemic in India: an ecological study

Rajib Acharya et al.

LANCET GLOBAL HEALTH (2020)

Article Public, Environmental & Occupational Health

Detection and Genetic Characterization of Community-Based SARS-CoV-2 Infections - New York City, March 2020

Dena Bushman et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

Article Microbiology

A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

Andrew Rambaut et al.

NATURE MICROBIOLOGY (2020)

Article Medicine, General & Internal

COVID-19 resurgence in Iran

Sharmila Devi

LANCET (2020)

Article Infectious Diseases

Association between mobility patterns and COVID-19 transmission in the USA: a mathematical modelling study

Hamada S. Badr et al.

LANCET INFECTIOUS DISEASES (2020)

Article Biochemistry & Molecular Biology

Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

Leonid Yurkovetskiy et al.

Article Multidisciplinary Sciences

Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe

Seth Flaxman et al.

NATURE (2020)

Article Multidisciplinary Sciences

Reconstruction of the full transmission dynamics of COVID-19 in Wuhan

Xingjie Hao et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling

Rebecca J. Rockett et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

Bas B. Oude Munnink et al.

NATURE MEDICINE (2020)

Editorial Material Biochemistry & Molecular Biology

COVID-19 in Africa: the spread and response

Marguerite Massinga Loembe et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

Seroprevalence of immunoglobulin M and G antibodies against SARS-CoV-2 in China

Xin Xu et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

Population-based surveys of antibodies against SARS-CoV-2 in Southern Brazil

Mariangela F. Silveira et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

Antoni G. Wrobel et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)

Article Multidisciplinary Sciences

Evolution and epidemic spread of SARS-CoV-2 in Brazil

Darlan S. Candido et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

Hongjing Gu et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City region

Matthew T. Maurano et al.

GENOME RESEARCH (2020)

Letter Public, Environmental & Occupational Health

Countries of origin of imported COVID-19 cases into China and measures to prevent onward transmission

Zhou-Bin Zhang et al.

JOURNAL OF TRAVEL MEDICINE (2020)

Article Public, Environmental & Occupational Health

Uncovering two phases of early intercontinental COVID-19 transmission dynamics

Jing Yang et al.

JOURNAL OF TRAVEL MEDICINE (2020)

Article Multidisciplinary Sciences

Estimating unobserved SARS-CoV-2 infections in the United States

T. Alex Perkins et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Cryptic transmission of SARS-CoV-2 in Washington state

Trevor Bedford et al.

SCIENCE (2020)

Article Public, Environmental & Occupational Health

Excess Deaths Associated with COVID-19, by Age and Race and Ethnicity — United States, January 26–October 3, 2020

Lauren M. Rossen et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

Editorial Material Multidisciplinary Sciences

Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing

Xinghuo Pang et al.

NATIONAL SCIENCE REVIEW (2020)

Article Virology

Temporal signal and the phylodynamic threshold of SARS-CoV-2

Sebastian Duchene et al.

VIRUS EVOLUTION (2020)

Letter Medicine, General & Internal

Seropositive Prevalence of Antibodies Against SARS-CoV-2 in Wuhan, China

Anding Liu et al.

JAMA NETWORK OPEN (2020)

Article Multidisciplinary Sciences

Underdetection of cases of COVID-19 in France threatens epidemic control

Giulia Pullano et al.

NATURE (2020)

Letter Medicine, General & Internal

Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer

Teresa Aydillo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Multidisciplinary Sciences

Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China

Shiyi Cao et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

Lizhou Zhang et al.

NATURE COMMUNICATIONS (2020)

Article Genetics & Heredity

The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR

Shuhui Song et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2020)

Article Psychology, Biological

Ranking the effectiveness of worldwide COVID-19 government interventions

Nils Haug et al.

NATURE HUMAN BEHAVIOUR (2020)

Article Multidisciplinary Sciences

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

Yixuan J. Hou et al.

SCIENCE (2020)

Article Immunology

Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

Shin Murakami et al.

EMERGING INFECTIOUS DISEASES (2020)

Article Multidisciplinary Sciences

Differential effects of intervention timing on COVID-19 spread in the United States

Sen Pei et al.

SCIENCE ADVANCES (2020)

Article Multidisciplinary Sciences

Epidemiology and transmission dynamics of COVID-19 in two Indian states

Ramanan Laxminarayan et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Revealing fine-scale spatiotemporal differences in SARS-CoV-2 introduction and spread

Gage K. Moreno et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Full genome viral sequences inform patterns of SARS-CoV-2 spread into and within Israel

Danielle Miller et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Genomic surveillance of COVID-19 cases in Beijing

Pengcheng Du et al.

NATURE COMMUNICATIONS (2020)

Review Microbiology

Tracking virus outbreaks in the twenty-first century

Nathan D. Grubaugh et al.

NATURE MICROBIOLOGY (2019)

Article Biochemical Research Methods

Nextstrain: real-time tracking of pathogen evolution

James Hadfield et al.

BIOINFORMATICS (2018)

Review Pharmacology & Pharmacy

MERS-CoV spike protein: Targets for vaccines and therapeutics

Qihui Wang et al.

ANTIVIRAL RESEARCH (2016)

Review Biochemistry & Molecular Biology

Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond

Guangwen Lu et al.

TRENDS IN MICROBIOLOGY (2015)

Article Biochemical Research Methods

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

Alexandros Stamatakis

BIOINFORMATICS (2014)

Article Multidisciplinary Sciences

RNA 3′-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

Mickael Bouvet et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)