4.3 Article

Dihydrobenzofurans and Propynylthiophenes From the Roots of Eupatorium heterophyllum

Journal

NATURAL PRODUCT COMMUNICATIONS
Volume 17, Issue 1, Pages -

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/1934578X211072331

Keywords

Eupatorium heterophyllum; Asteraceae; benzofuran; thiophene; chemical diversity

Funding

  1. Japanese Society for the Promotion of Science [16K18897, 20K07102]
  2. Grants-in-Aid for Scientific Research [20K07102] Funding Source: KAKEN

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Seven new compounds were isolated from the roots of Eupatorium heterophyllum, along with 2 new compounds. Spectroscopic techniques were used for characterization. The chemical diversity in the roots was found to be lower than in the aerial parts.
Seven new dihydrobenzofurans and 2 new propynyl thiophenes were isolated from the roots of Eupatorium heterophyllum together with 13 known compounds. The compounds were characterized using spectroscopic methods including 2D NMR, infrared, and mass spectrometric techniques. Aerial parts of this plant have been known to contain various sesquiterpenoids and displayed high chemical diversity (several compounds isolated and/or identified) among their chemical constituents depending on the collection site. Nevertheless, we found that the chemical diversity in the roots was lower than in the aerial parts.

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