Journal
MONATSHEFTE FUR CHEMIE
Volume 152, Issue 11, Pages 1369-1375Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-021-02856-x
Keywords
Isocyanides; Isonicotinamide; Pentafluoropyridine; Emidoyl fluoride; Aromatic nucleophilic substitution
Categories
Funding
- Vali-e-Asr University of Rafsanjan
Ask authors/readers for more resources
The reactivity of some isocyanides with pentafluoropyridine under basic conditions in dry dimethyl sulfoxide was investigated, revealing different selectivity in the reactions. The structures of all compounds were confirmed through various spectroscopic methods and elemental analysis.
Reactivity of some isocyanides with pentafluoropyridine under basic conditions in dry dimethyl sulfoxide was investigated. The reaction of pentafluoropyridine with toluenesulfonylmethyl isocyanide (TosMIC) was less selective, but the reactions of other isocyanides with pentafluoropyridine gave the desired 2,3,5,6-tetrafluoro-N-substituted isonicotinamide. The structures of all the compounds were confirmed by IR, H-1 NMR, F-19 NMR, and C-13 NMR spectroscopy, X-ray crystallography as well as elemental analysis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
