Rapid Determination and Quality Control of Pharmacological Volatiles of Turmeric (Curcuma longa L.) by Fast Gas Chromatography-Surface Acoustic Wave Sensor

Article Cell Biology

Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities

Yuria Hori et al.

Summary: The study identified ar-turmerone analogs that directly and potently protected dopaminergic neurons, even independently of microglial activation inhibition, possibly involving nuclear factor erythroid 2-related factor 2.

CELLS (2021)

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Article Anatomy & Morphology

Curcuma longa L. Effects on Akt/mTOR Pathway and NF-?B Expression During Skin Wound Healing: An Immunohistochemical Study

Chris K. Danilevicz et al.

Summary: The study shows that mucoadhesive formulation with Curcuma longa L. extract accelerates cutaneous wound repair by modulating the inflammatory process and stimulating re-epithelization through an Akt/mTOR-dependent mechanism.

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2021)

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Article Chemistry, Multidisciplinary

Characterization of the Volatile Profile of Cultivated and Wild-Type Italian Celery (Apium graveolens L.) Varieties by HS-SPME/GC-MS

Samantha Reale et al.

Summary: This study examined the volatile profiles of different celery varieties and revealed distinct differences in flavor composition among them, with potential chemical components useful for classification of celery based on variety/origin. Exploratory multivariate statistical analyses using principal component analysis (PCA) showed clear differentiation between wild-type celery and cultivated varieties, particularly black celery Sedano Nero di Torricella Peligna.

APPLIED SCIENCES-BASEL (2021)

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Article Cell Biology

Anti-inflammatory and Antioxidant Activity of Nanoencapsulated Curcuminoids Extracted from Curcuma longa L. in a Model of Cutaneous Inflammation

Emanuele P. Lima et al.

Summary: The study found that nanoencapsulated curcuminoid preparations and free curcuminoids had similar anti-inflammatory effects in topical treatment, while oral administration of nanoencapsulated curcuminoid preparations had a higher anti-inflammatory effect than free curcuminoids. Additionally, nanoencapsulated curcuminoid preparations showed better bioavailability compared to free curcuminoids.

INFLAMMATION (2021)

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Article Plant Sciences

The influence of Javanese turmeric (Curcuma xanthorrhiza) on the pharmacokinetics of warfarin in rats with single and multiple-dose studies

Taofik Rusdiana et al.

Summary: The study found that co-administration of Curcuma xanthorrhiza Roxb. extract and warfarin affected the pharmacokinetics of warfarin in rats, indicating the need for further clinical evaluation of the interaction.

PHARMACEUTICAL BIOLOGY (2021)

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Article Chemistry, Analytical