Journal
MOLECULES
Volume 27, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/molecules27030948
Keywords
stimuli-responsive; drug delivery; lung cancer
Funding
- aboratory of Life Sciences and Biomedicine of Zhejiang Province, Westlake University
- National Natural Science Foundation [82073297]
- Hangzhou Major Science and Technology Project [20172016A01]
- Natural Science Foundation of Zhejiang Province [LY20H310005, LQ22H180009]
- Clinical Pharmacy of Hangzhou Medical Key Discipline [2021-21-16]
- Postdoctoral Research Foundation of China [2021M702876]
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Lung cancer is the most commonly diagnosed cancer worldwide, and the development of smart carriers for drug delivery presents a promising strategy for therapy.
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death worldwide. Numerous drugs have been developed to treat lung cancer patients in recent years, whereas most of these drugs have undesirable adverse effects due to nonspecific distribution in the body. To address this problem, stimuli-responsive drug delivery systems are imparted with unique characteristics and specifically deliver loaded drugs at lung cancer tissues on the basis of internal tumor microenvironment or external stimuli. This review summarized recent studies focusing on the smart carriers that could respond to light, ultrasound, pH, or enzyme, and provided a promising strategy for lung cancer therapy.
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