Related references
Note: Only part of the references are listed.Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
Muhammad Issa Khan et al.
MOLECULES (2021)
Withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug
Behrouz Hassannia et al.
BIOCHEMICAL PHARMACOLOGY (2020)
New withanolides with anti-inflammatory activity from the leaves of Datura metel L.
Jinyan Tan et al.
BIOORGANIC CHEMISTRY (2020)
Isolation and characterization of cytotoxic withanolides from the calyx of Physalis alkekengi L. var franchetii
Yi Sun et al.
BIOORGANIC CHEMISTRY (2020)
Anti-angiogenesis Potential of Phytochemicals for the Therapeutic Management of Tumors
Samman Munir et al.
CURRENT PHARMACEUTICAL DESIGN (2020)
Overview of the anticancer activity of withaferin A, an active constituent of the Indian ginseng Withania somnifera
Vishnu Sankar Sivasankarapillai et al.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020)
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2020)
ASR488, a novel small molecule, activates an mRNA binding protein, CPEB1, and inhibits the growth of bladder cancer
Ashish Tyagi et al.
ONCOLOGY LETTERS (2020)
Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action
Anissa Nofita Sari et al.
CANCERS (2020)
Withania somnifera (L.) Dunal: A potential therapeutic adjuvant in cancer
Akash Saggam et al.
JOURNAL OF ETHNOPHARMACOLOGY (2020)
Natural Bioactive New Withanolides
Qian-Qian Xu et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2020)
ASR490, a Small Molecule, Overrides Aberrant Expression of Notch1 in Colorectal Cancer
Ashish Tyagi et al.
MOLECULAR CANCER THERAPEUTICS (2020)
Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes
Marilia Barreca et al.
MARINE DRUGS (2020)
Choking cancer: Developing a pathway of Withaferin A for the prevention of angiogenesis
Rishab Rajeev Samant et al.
CANCER RESEARCH (2020)
Daturanolide A-C, Three New Withanolides from Datura metel L. and Their Cytotoxic Activities
Xiao-Yan Wang et al.
CHEMISTRY & BIODIVERSITY (2019)
Cytotoxic Withanolides from the Roots of Indian Ginseng (Withania somnifera)
Sil Kim et al.
JOURNAL OF NATURAL PRODUCTS (2019)
Expanding the Chemical Space of Withaferin A by Incorporating Silicon To Improve Its Clinical Potential on Human Ovarian Carcinoma Cells
Nayra R. Perestelo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea
Sebastian J. Castro et al.
JOURNAL OF NATURAL PRODUCTS (2019)
Cytotoxic Withanolides from the Whole Herb of Physalis angulata L.
Qinghong Meng et al.
MOLECULES (2019)
Withanolides and 26-Hydroxylated Derivatives with Anti-Inflammatory Property from Solanum Capsicoide
You-Cheng Lin et al.
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2019)
Cancer statistics, 2019
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2019)
Research advances on anticancer activities of matrine and its derivatives: An updated overview
Haroon Ur Rashid et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Indole: A privileged scaffold for the design of anti-cancer agents
Yichao Wan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Metabolomic and biotechnological approaches to determine therapeutic potential of Withania somnifera (L.) Dunal: A review
Niraj Tripathi et al.
PHYTOMEDICINE (2018)
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
Behrouz Hassannia et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Physalis alkekengi L. var. franchetii (Mast.) Makino: An ethnomedical, phytochemical and pharmacological review
Ai-Ling Li et al.
JOURNAL OF ETHNOPHARMACOLOGY (2018)
Antidiabetic potential of the ethyl acetate extract of Physalis alkekengi and chemical constituents identified by HPLC-ESI-QTOF-MS
Qiang Zhang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2018)
Advances in studies of tyrosine kinase inhibitors and their acquired resistance
Qinlian Jiao et al.
MOLECULAR CANCER (2018)
An Adaptogen: Withaferin A Ameliorates in Vitro and in Vivo Pulmonary Fibrosis by Modulating the Interplay of Fibrotic, Matricelluar Proteins, and Cytokines
Swarna Bale et al.
FRONTIERS IN PHARMACOLOGY (2018)
Epigenetic anticancer agents cause HMGB1 release in vivo
Peng Liu et al.
ONCOIMMUNOLOGY (2018)
Cytotoxic withanolides from the aerial parts of Tubocapsicum anomalum
Si-Bei Wang et al.
BIOORGANIC CHEMISTRY (2018)
Withaferin A inhibits apoptosis via activated Akt-mediated inhibition of oxidative stress
Zheyi Yan et al.
LIFE SCIENCES (2018)
Biological Activities of Four Adaptogenic Plant Extracts and Their Active Substances on a Rotifer Model
Lilla Macsai et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)
Withanolides and aromatic glycosides isolated from Nicandra physaloides and their anti-inflammatory activity
Peng Zhang et al.
FITOTERAPIA (2018)
Withaferin A, a novel compound of Indian ginseng (Withania somnifera), ameliorates Cerulein-induced acute pancreatitis: Possible role of oxidative stress and inflammation
Vijaya Lakshmi Tiruveedi et al.
PHYTOTHERAPY RESEARCH (2018)
The Anti-inflammatory Activities of Two Major Withanolides from Physalis minima Via Acting on NF-κB, STAT3, and HO-1 in LPS-Stimulated RAW264.7 Cells
Rui-Jun Li et al.
INFLAMMATION (2017)
Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers
Gabriel G. Llanos et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells
Ya-Ming Xu et al.
JOURNAL OF NATURAL PRODUCTS (2017)
Phenylpropanoids from the fruits of Nicandra physaloides and their anti-inflammatory activities
Bing You Yang et al.
NATURAL PRODUCT RESEARCH (2017)
Regiospecific Synthesis of Ring A Fused Withaferin A Isoxazoline Analogues: Induction of Premature Senescence by W-2b in Proliferating Cancer Cells
Faheem Rasool et al.
SCIENTIFIC REPORTS (2017)
Bioactive new withanolides from the cultured soft coral Sinularia brassica
Chiung-Yao Huang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Anticancer activities of Withania somnifera: Current research, formulations, and future perspectives
Mahendra Rai et al.
PHARMACEUTICAL BIOLOGY (2016)
Withanolides derived from Physalis peruviana (Poha) with potential anti-inflammatory activity
Mayuramas Sang-ngern et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
13,14-seco-Withanolides from Physalis minima with Potential Anti-inflammatory Activity
Ru Lin et al.
CHEMISTRY & BIODIVERSITY (2016)
Chemical Constituents and Biological Activities of Plants from the Genus Physalis
Wen-Na Zhang et al.
CHEMISTRY & BIODIVERSITY (2016)
1H NMR spectroscopy-guided isolation of new sucrose esters from Physalis alkekengi var. franchetii and their antibacterial activity
Chuan-Yang Zhang et al.
FITOTERAPIA (2016)
17β-Hydroxy-18-acetoxywithanolides from Aeroponically Grown Physalis crassifolia and Their Potent and Selective Cytotoxicity for Prostate Cancer Cells
Ya-ming Xu et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Antiproliferative and Anti-inflammatory Withanolides from Physalis angulata
Cheng-Peng Sun et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Natural Products as Sources of New Drugs from 1981 to 2014
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Withanolides from leaves of cultivated Acnistus arborescens
Pedro Henrique J. Batista et al.
PHYTOCHEMISTRY (2016)
Withaphysalin-type withanolides from Physalis minima
Xiao-Ming Xu et al.
PHYTOCHEMISTRY LETTERS (2016)
Withanolides from the stems and leaves of Physalis pubescens and their cytotoxic activity
Guiyang Xia et al.
STEROIDS (2016)
Cytotoxic withanolides from Physalis angulata var. villosa and the apoptosis-inducing effect via ROS generation and the activation of MAPK in human osteosarcoma cells
Ting Ma et al.
RSC ADVANCES (2016)
MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer
Han-Li Huang et al.
SCIENTIFIC REPORTS (2016)
Inhibition of Monosodium Urate Crystal-Induced Inflammation by Withaferin A
Mahaboobkhan Rasool et al.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2016)
Plantagiolides K-N, three new withanolides and one withanolide glucoside from Tacca plantaginea
Zhen-Hua Liu et al.
FITOTERAPIA (2015)
Discovery of Potent 17β-Hydroxywithanolides for Castration-Resistant Prostate Cancer by High-Throughput Screening of a Natural Products Library for Androgen-Induced Gene Expression Inhibitors
Ya-Ming Xu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Withanolides and Sucrose Esters from Physalis neomexicana
Cong-Mei Cao et al.
JOURNAL OF NATURAL PRODUCTS (2015)
Withanolides with Antibacterial Activity from Nicandra john-tyleriana
Fatima Gutierrez Nicolas et al.
JOURNAL OF NATURAL PRODUCTS (2015)
Withanolides from Physalis coztomatl
Huaping Zhang et al.
PHYTOCHEMISTRY (2015)
Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation
C. J. Henrich et al.
CELL DEATH & DISEASE (2015)
Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ
Karen Heyninck et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Structure Activity Relationships for Withanolides as Inducers of the Cellular Heat-Shock Response
E. M. Kithsiri Wijeratne et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
New Horizons for Old Drugs and Drug Leads
Gordon M. Cragg et al.
JOURNAL OF NATURAL PRODUCTS (2014)
Five Withanolides from the Leaves of Datura metel L. and Their Inhibitory Effects on Nitric Oxide Production
Bing-You Yang et al.
MOLECULES (2014)
Anti-inflammatory Activities of an Active Fraction Isolated from the root of Astragalus membranaceus in RAW 264.7 Macrophages
Patrick Kwok-Kin Lai et al.
PHYTOTHERAPY RESEARCH (2014)
Induction of quinone reductase (QR) by withanolides isolated from Physalis angulata L. var. villosa Bonati (Solanaceae)
Hui Ding et al.
STEROIDS (2014)
New anti-inflammatory withanolides from the leaves of Datura metel L.
Bing-You Yang et al.
STEROIDS (2014)
Natural products: A continuing source of novel drug leads
Gordon M. Cragg et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Targeting the hallmarks of cancer: towards a rational approach to next-generation cancer therapy
Pierre Hainaut et al.
CURRENT OPINION IN ONCOLOGY (2013)
Physangulidine A, a Withanolide from Physalis angulata, Perturbs the Cell Cycle and Induces Cell Death by Apoptosis in Prostate Cancer Cells
E. Merit Reyes-Reyes et al.
JOURNAL OF NATURAL PRODUCTS (2013)
Antiproliferative Withanolides from Datura wrightii
Huaping Zhang et al.
JOURNAL OF NATURAL PRODUCTS (2013)
Withanolide-Based Steroids from the Cultured Soft Coral Sinularia brassica
Chiung-Yao Huang et al.
JOURNAL OF NATURAL PRODUCTS (2013)
Biologically Active Withanolides from Withania coagulans
Ihsan-ul-Haq et al.
JOURNAL OF NATURAL PRODUCTS (2013)
Cytotoxic withanolides from the leaves of Moroccan Withania frutescens
Laila El Bouzidi et al.
PHARMACEUTICAL BIOLOGY (2013)
Induction of quinone reductase (QR) by withanolides isolated from Physalis pubescens L. (Solanaceae)
Long Ji et al.
STEROIDS (2013)
Synthesis and Cytotoxicity of Semisynthetic Withalongolide A Analogues
Hashim F. Motiwala et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Molecular insight in the multifunctional activities of Withaferin A
Wim Vanden Berghe et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Leishmanicidal Active Withanolides from a Pakistani Medicinal Plant, Withania coagulans
Masanori Kuroyanagi et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2012)
Molecular cloning, bacterial expression and promoter analysis of squalene synthase from Withania somnifera (L.) Dunal
Wajid Waheed Bhat et al.
GENE (2012)
Biaryl-Bridged Macrocyclic Peptides: Conformational Constraint via Carbogenic Fusion of Natural Amino Acid Side Chains
Falco-Magnus Meyer et al.
JOURNAL OF ORGANIC CHEMISTRY (2012)
Physangulidines A, B, and C: Three New Antiproliferative Withanolides from Physalis angulata L.
Zhuang Jin et al.
ORGANIC LETTERS (2012)
Antiproliferative withanolides from the Solanaceae: A structure-activity study
Huaping Zhang et al.
PURE AND APPLIED CHEMISTRY (2012)
Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors
Long Ji et al.
STEROIDS (2012)
Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models
Wonhwa Lee et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Macrophage-Mediated Lymphangiogenesis: The Emerging Role of Macrophages as Lymphatic Endothelial Progenitors
Sophia Ran et al.
Cancers (2012)
AN OVERVIEW ON ASHWAGANDHA: A RASAYANA (REJUVENATOR) OF AYURVEDA
Narendra Singh et al.
AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Withanolides from the Rhizomes of Dioscorea japonica and Their Cytotoxicity
Ki Hyun Kim et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)
Dinoxin B, a Withanolide from Datura inoxia Leaves with Specific Cytotoxic Activities
Karl Vermillion et al.
JOURNAL OF NATURAL PRODUCTS (2011)
Cytotoxic Withanolide Constituents of Physalis longifolia
Huaping Zhang et al.
JOURNAL OF NATURAL PRODUCTS (2011)
Paraminabeolides A-F, Cytotoxic and Anti-inflammatory Marine Withanolides from the Soft Coral Paraminabea acronocephala
Chih-Hua Chao et al.
JOURNAL OF NATURAL PRODUCTS (2011)
Two New Withanolide Lactones from Flos Daturae
Hai-Xue Kuang et al.
MOLECULES (2011)
Natural withanolides: an overview
Li-Xia Chen et al.
NATURAL PRODUCT REPORTS (2011)
Ring A structural modified derivatives of withaferin A and the evaluation of their cytotoxic potential
Syed Khalid Yousuf et al.
STEROIDS (2011)
Resveratrol and derivatives for the prevention and treatment of cancer
Simone Fulda
DRUG DISCOVERY TODAY (2010)
Withanolides from Withania aristata and their cytotoxic activity
Gabriel G. LLanos et al.
STEROIDS (2010)
Thermodynamic and Structural Effects of Macrocyclic Constraints in Protein-Ligand Interactions
John E. DeLorbe et al.
ACS MEDICINAL CHEMISTRY LETTERS (2010)
2,3-Dihydrowithaferin A-3β-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera
Ya-ming Xu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe
Bharat B. Aggarwal et al.
CLINICAL CANCER RESEARCH (2009)
Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation
Rangan Maitra et al.
JOURNAL OF INFLAMMATION-LONDON (2009)
Selective reactivity of 2-mercaptoethanol with 5β,6β-epoxide in steroids from Withania somnifera
Laxminarain Misra et al.
STEROIDS (2008)
Discovery of novel isoxazolines as anti-tuberculosis agents
Rajendra P. Tangallapally et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
High-throughput, high-sensitivity analysis of gene expression in arabidopsis
Richard Martin Kris et al.
PLANT PHYSIOLOGY (2007)
Isolation, structures, and structure-cytotoxic activity relationships of withanolides and physalins from Physalis angulata
Amooru G. Damu et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Cytotoxic withanolides from Tubocapsicum anomalum
Pei-Wen Hsieh et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Chronic inflammation:: importance of NOD2 and NALP3 in interleukin-1β generation
L. Ferrero-Miliani et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
Seed structure and dormancy of Nicandra physalodes (Solanaceae)
R. Lovey et al.
SEED SCIENCE AND TECHNOLOGY (2007)
Resolvins and protectins in the termination program of acute inflammation
Amirarn Ariel et al.
TRENDS IN IMMUNOLOGY (2007)
Cytotoxic withaphysalins from Physalis minima
Lei Ma et al.
HELVETICA CHIMICA ACTA (2007)
n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
Philip C. Calder
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
Daturametelins H, I, and J: Three new withanolide glycosides from Datura metel L.
L Ma et al.
CHEMISTRY & BIODIVERSITY (2006)
Promoting apoptosis as a strategy for cancer drug discovery
SW Fesik
NATURE REVIEWS CANCER (2005)
Old meets new: The interaction between innate and adaptive immunity
R Clark et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)
Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves
B Jayaprakasam et al.
LIFE SCIENCES (2003)
Adaptogenic activity of Withania somnifera:: an experimental study using a rat model of chronic stress
SK Bhattacharya et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2003)
Activity-guided isolation of novel norwithanolides from Deprea subtriflora with potential cancer chemopreventive activity
BN Su et al.
JOURNAL OF ORGANIC CHEMISTRY (2003)
Anti-inflammatory lipid mediators and insights into the resolution of inflammation
T Lawrence et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Withanolide derivatives from the roots of Withania somnifera and their neurite outgrowth activities
J Zhao et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2002)
Induction of quinone reductase by withanolides
RI Misico et al.
JOURNAL OF NATURAL PRODUCTS (2002)
Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity
RA Isbrucker et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2001)
Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides:: an experimental study
SK Bhattacharya et al.
PHYTOMEDICINE (2000)
Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica
G Mareggiani et al.
JOURNAL OF NATURAL PRODUCTS (2000)
Antifeedant activity evaluation of withanolides from Jaborosa integrifolia
CE Vaccarini et al.
MOLECULES (2000)
Share Paper
