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Prion Protein in Glioblastoma Multiforme
Larisa Ryskalin et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Formation of biological condensates via phase separation: Characteristics, analytical methods, and physiological implications
Zhe Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Role of hypoxia in cancer therapy by regulating the tumor microenvironment
Xinming Jing et al.
MOLECULAR CANCER (2019)
Cancer Etiology: A Metabolic Disease Originating from Life's Major Evolutionary Transition?
B. Poljsak et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Hydrogen bond guidance and aromatic stacking drive liquid-liquid phase separation of intrinsically disordered histidine-rich peptides
Bartosz Gabryelczyk et al.
NATURE COMMUNICATIONS (2019)
RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
Petar Stefanov Kovachev et al.
SCIENTIFIC REPORTS (2019)
Glycolytic Proteins Interact With Intracellular Melatonin in Saccharomyces cerevisiae
Maria Angeles Morcillo-Parra et al.
FRONTIERS IN MICROBIOLOGY (2019)
Stiffness and ATP recovery of stored red blood cells in serum
Zhensong Xu et al.
MICROSYSTEMS & NANOENGINEERING (2019)
Melatonin protects mesenchymal stem cells from autophagy-mediated death under ischaemic ER-stress conditions by increasing prion protein expression
Jun Hee Lee et al.
CELL PROLIFERATION (2019)
Iron Metabolism in Cancer
Yafang Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Cellular and Molecular Mechanisms Mediated by recPrPC Involved in the Neuronal Differentiation Process of Mesenchymal Stem Cells
Stefano Martellucci et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Relationship between inorganic ion distribution, resting membrane potential, and the ΔG′ of ATP hydrolysis: a new paradigm
Richard L. Veech et al.
FASEB JOURNAL (2019)
Computational study of metal complexes formed with EDTA, melatonin, and its main metabolites: implications in lead intoxication and clues to a plausible alternative treatment
Erik Diaz-Cervantes et al.
JOURNAL OF MOLECULAR MODELING (2019)
EGFR and Prion protein promote signaling via FOXO3a-KLF5 resulting in clinical resistance to platinum agents in colorectal cancer
Caroline J. Atkinson et al.
MOLECULAR ONCOLOGY (2019)
Review: PrP 106-126-25 years after
G. Forloni et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2019)
Melatonin Alleviates Copper Toxicity via Improving Copper Sequestration and ROS Scavenging in Cucumber
Yun-Yun Cao et al.
PLANT AND CELL PHYSIOLOGY (2019)
Protein Phase Separation as a Stress Survival Strategy
Titus M. Franzmann et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)
Melatonin regulates tumor aggressiveness under acidosis condition in breast cancer cell lines
Nathalia Martins Sonehara et al.
ONCOLOGY LETTERS (2019)
Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance
Jayshree Hirpara et al.
REDOX BIOLOGY (2019)
Drug-resistance reversal in colorectal cancer cells by destruction of flotillins, the key lipid rafts proteins
D. M. Ye et al.
NEOPLASMA (2019)
Antioxidant Defense Mechanisms in Erythrocytes and in the Central Nervous System
Rafael Franco et al.
ANTIOXIDANTS (2019)
Melatonin Protects Band 3 Protein in Human Erythrocytes against H2O2-Induced Oxidative Stress
Rossana Morabito et al.
MOLECULES (2019)
Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer
Adrian P. Wiegmans et al.
JCI INSIGHT (2019)
Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study
Juzar Jamnagerwalla et al.
PROSTATE CANCER AND PROSTATIC DISEASES (2018)
The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells
Sanchareeka Dey et al.
ONCOTARGET (2018)
Melatonin Promotes Apoptosis of Oxaliplatin-resistant Colorectal Cancer Cells Through Inhibition of Cellular Prion Protein
Jun Hee Lee et al.
ANTICANCER RESEARCH (2018)
Melatonin Promotes Apoptosis of Colorectal Cancer Cells via Superoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression
Chul Won Yun et al.
ANTICANCER RESEARCH (2018)
Targeted cancer therapy through 17-DMAG as an Hsp90 inhibitor: Overview and current state of the art
Hassan Mellatyar et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Cellular Prion Protein Enhances Drug Resistance of Colorectal Cancer Cells via Regulation of a Survival Signal Pathway
Jun Hee Lee et al.
BIOMOLECULES & THERAPEUTICS (2018)
Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression
Steven J. Collins et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Amyloid and the origin of life: self-replicating catalytic amyloids as prebiotic informational and protometabolic entities
Carl Peter J. Maury
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
Thomas M. Ashton et al.
CLINICAL CANCER RESEARCH (2018)
Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression
Yong Seok Han et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
FLVCR1 promotes the proliferation and tumorigenicity of synovial sarcoma through inhibiting apoptosis and autophagy
Changliang Peng et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2018)
Synergistic effect of thymoquinone and melatonin against breast cancer implanted in mice
Lena Hisham Odeh et al.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2018)
More than Just a Phase: Prions at the Crossroads of Epigenetic Inheritance and Evolutionary Change
Anupam K. Chakravarty et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma
Jule A. Eriksson et al.
JOURNAL OF NEUROCHEMISTRY (2018)
Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection
Annia Galano et al.
JOURNAL OF PINEAL RESEARCH (2018)
Quantifying Nucleation In Vivo Reveals the Physical Basis of Prion-like Phase Behavior
Tarique Khan et al.
MOLECULAR CELL (2018)
Protein-Based Inheritance: Epigenetics beyond the Chromosome
Zachary H. Harvey et al.
MOLECULAR CELL (2018)
Tolerance to Stress Combination in Tomato Plants: New Insights in the Protective Role of Melatonin
Vicente Martinez et al.
MOLECULES (2018)
Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway
Jun Song et al.
ONCOLOGY REPORTS (2018)
Phase separation of a yeast prion protein promotes cellular fitness
Titus M. Franzmann et al.
SCIENCE (2018)
A new free radical scavenging cascade involving melatonin and three of its metabolites (3OHM, AFMK and AMK)
Miguel Reina et al.
COMPUTATIONAL AND THEORETICAL CHEMISTRY (2018)
Manipulating extracellular tumour pH: an effective target for cancer therapy
Guanyu Hao et al.
RSC ADVANCES (2018)
Prion protein modulates glucose homeostasis by altering intracellular iron
Ajay Ashok et al.
SCIENTIFIC REPORTS (2018)
Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism
Wangie Yu et al.
SCIENTIFIC REPORTS (2018)
Pi-Pi contacts are an overlooked protein feature relevant to phase separation
Robert McCoy Vernon et al.
ELIFE (2018)
Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli
Michael H. Hayes et al.
ELIFE (2018)
Protective Role of Intracellular Melatonin Against Oxidative Stress and UV Radiation in Saccharomyces cerevisiae
Ricardo Bisquert et al.
FRONTIERS IN MICROBIOLOGY (2018)
Squeezing for Life - Properties of Red Blood Cell Deformability
Rick Huisjes et al.
FRONTIERS IN PHYSIOLOGY (2018)
Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome
Do-Wan Shim et al.
FRONTIERS IN IMMUNOLOGY (2018)
ATP enhances at low concentrations but dissolves at high concentrations liquid-liquid phase separation (LLPS) of ALS/FTD-causing FUS
Jian Kang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
A D-enantiomeric peptide interferes with heteroassociation of amyloid-beta oligomers and prion protein
Nadine S. Roesener et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis
Jun Hee Lee et al.
JOURNAL OF PINEAL RESEARCH (2018)
Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition
Sai Ma et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Systems analysis of intracellular pH vulnerabilities for cancer therapy
Erez Persi et al.
NATURE COMMUNICATIONS (2018)
Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC
Soohyun Lee et al.
SCIENTIFIC REPORTS (2018)
Effect of Cholesterol on Membrane Fluidity and Association of A beta Oligomers and Subsequent Neuronal Damage: A Double-Edged Sword
Eduardo J. Fernandez-Perez et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
The Effect of Melatonin on Superoxide Dismutase and Glutathione Peroxidase Activity, and Malondialdehyde Levels in the Targeted and the non-targeted Lung and Heart Tissues after Irradiation in Xenograft Mice Colon Cancer
Seyede Hadis Momeni Hasan Abadi et al.
CURRENT MOLECULAR PHARMACOLOGY (2018)
Melatonin Promotes Ubiquitination of Phosphorylated Pro-Apoptotic Protein Bcl-2-Interacting Mediator of Cell Death-Extra Long (Bim(EL)) in Porcine Granulosa Cells
Yingzheng Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules
Zaira Boussadia et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Liquid and Hydrogel Phases of PrPC Linked to Conformation Shifts and Triggered by Alzheimer's Amyloid-β Oligomers
Mikhail A. Kostylev et al.
MOLECULAR CELL (2018)
Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis
Sarada Preeta Kalainayakan et al.
CELL AND BIOSCIENCE (2018)
Regulation of NLRP3 Inflammasome by Phosphorylation
Nan Song et al.
FRONTIERS IN IMMUNOLOGY (2018)
Metabolic Reprogramming of Non-Hodgkin's B-Cell Lymphomas and Potential Therapeutic Strategies
Jean-Ehrland Ricci et al.
FRONTIERS IN ONCOLOGY (2018)
A quantitative characterization of interaction between prion protein with nucleic acids
Alakesh Bera et al.
BIOCHEMISTRY AND BIOPHYSICS REPORTS (2018)
Mutations Alter RNA-Mediated Conversion of Human Prions
Erik J. Alred et al.
ACS OMEGA (2018)
Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins
Xiongyi Huang et al.
CHEMICAL REVIEWS (2018)
Cancer metastasis: Mechanisms of inhibition by melatonin
Shih-Chi Su et al.
JOURNAL OF PINEAL RESEARCH (2017)
Insulin enhances the peroxidase activity of heme by forming heme-insulin complex: Relevance to type 2 diabetes mellitus
Yi Huang et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)
Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis
Russel J. Reiter et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Epigenetic inheritance, prions and evolution
Johannes Manjrekar
JOURNAL OF GENETICS (2017)
LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface
O. Salvesen et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Membrane Disruption Mechanism of a Prion Peptide (106-126) Investigated by Atomic Force Microscopy, Raman and Electron Paramagnetic Resonance Spectroscopy
Jianjun Pan et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2017)
Melatonin impedes Tet1-dependent mGluR5 promoter demethylation to relieve pain
Ming-Chun Hsieh et al.
JOURNAL OF PINEAL RESEARCH (2017)
Potentiation of biological effects of mesenchymal stem cells in ischemic conditions by melatonin via upregulation of cellular prion protein expression
Jun Hee Lee et al.
JOURNAL OF PINEAL RESEARCH (2017)
Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome
Zhengwang Cao et al.
JOURNAL OF PINEAL RESEARCH (2017)
Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma
Shibo Lin et al.
JOURNAL OF PINEAL RESEARCH (2017)
Increased expression of prion protein gene is accompanied by demethylation of CpG sites in a mouse embryonal carcinoma cell line, P19C6
Wuyun Dalai et al.
JOURNAL OF VETERINARY MEDICAL SCIENCE (2017)
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
Yalikun Suofu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
ATP as a biological hydrotrope
Avinash Patel et al.
SCIENCE (2017)
Physical and biological characteristics of multi drug resistance (MDR): An integral approach considering pH and drug resistance in cancer
Ziad Omran et al.
SEMINARS IN CANCER BIOLOGY (2017)
Full-Length Anion Exchanger 1 Structure and Interactions with Ankyrin-1 Determined by Zero Length Crosslinking of Erythrocyte Membranes
Roland Rivera-Santiago et al.
STRUCTURE (2017)
Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure
Sergey V. Ulianov et al.
EPIGENETICS & CHROMATIN (2017)
Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level increase
Xuan Wang et al.
ONCOTARGET (2017)
Extracellular pH is a biomarker enabling detection of breast cancer and liver cancer using CEST MRI
Miaomiao Chen et al.
ONCOTARGET (2017)
Cellular prion protein is present in mitochondria of healthy mice
Robert Faris et al.
SCIENTIFIC REPORTS (2017)
Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress
Meiyan Jin et al.
CELL REPORTS (2017)
Prion-Like Protein Aggregates and Type 2 Diabetes
Abhisek Mukherjee et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
Pedro M. Aponte et al.
STEM CELLS INTERNATIONAL (2017)
Effects of Hypoxia on Erythrocyte Membrane Properties-Implications for Intravascular Hemolysis and Purinergic Control of Blood Flow
Ryszard Grygorczyk et al.
FRONTIERS IN PHYSIOLOGY (2017)
Post-translational modifications in PrP expand the conformational diversity of prions in vivo
Patricia Aguilar-Calvo et al.
SCIENTIFIC REPORTS (2017)
Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism
Jose Maria Moreno-Navarrete et al.
SCIENTIFIC REPORTS (2017)
The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells
Maryam Akbarzadeh et al.
SCIENTIFIC REPORTS (2017)
Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation
Mark Borris D. Aldonza et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2017)
Synergistic Cytotoxicity of Melatonin and New-generation Anticancer Drugs Against Leukemia Lymphocytes But Not Normal Lymphocytes
Zhivko Zhelev et al.
ANTICANCER RESEARCH (2017)
Iron metabolism and drug resistance in cancer
Hasan Huseyin Kazan et al.
BIOMETALS (2017)
Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas
Russel J. Reiter et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Diverse functions of the prion protein - Does proteolytic processing hold the key?
Luise Linsenrneier et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)
Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin
Qing Chen et al.
ANTI-CANCER DRUGS (2017)
Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis
Benjamin Ruprecht et al.
CANCER RESEARCH (2017)
Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response
Joshua A. Riback et al.
CELL (2017)
Physiological Functions of the Cellular Prion Protein
Andrew R. Castle et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2017)
Targeting the lysosome in cancer
Shengfu Piao et al.
TARGETING THE LYSOSOME (2016)
Prions are affected by evolution at two levels
Reed B. Wickner et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia
Narges K. Tafreshi et al.
MOLECULAR IMAGING AND BIOLOGY (2016)
Silencing Prion Protein in HT29 Human Colorectal Cancer Cells Enhances Anticancer Response to Fucoidan
Chul Won Yun et al.
ANTICANCER RESEARCH (2016)
Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context
Reinhart A. F. Reithmeier et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)
Glucose-based microbial production of the hormone melatonin in yeast Saccharomyces cerevisiae
Susanne M. Germann et al.
BIOTECHNOLOGY JOURNAL (2016)
Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O2 regulation of erythrocyte properties
Haiyan Chu et al.
BLOOD (2016)
Heme Iron Intake, Dietary Antioxidant Capacity, and Risk of Colorectal Adenomas in a Large Cohort Study of French Women
Nadia Bastide et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2016)
Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits
Sohini Chakrabortee et al.
CELL (2016)
The role of cholesterol in membrane fusion
Sung-Tae Yang et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2016)
Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics
Dun-Xian Tan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines
Nesstor Pilco-Ferreto et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease
Ajai K. Tripathi et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Proton Fall or Bicarbonate Rise GLYCOLYTIC RATE IN MOUSE ASTROCYTES IS PAVED BY INTRACELLULAR ALKALINIZATION
Shefeeq M. Theparambil et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Oligomers of Amyloid Prevent Physiological Activation of the Cellular Prion Protein-Metabotropic Glutamate Receptor 5 Complex by Glutamate in Alzheimer Disease
Laura T. Haas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species
Dun-Xian Tan et al.
JOURNAL OF PINEAL RESEARCH (2016)
Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome
Yong Zhang et al.
JOURNAL OF PINEAL RESEARCH (2016)
RNA Remodeling Activity of DEAD Box Proteins Tuned by Protein Concentration, RNA Length, and ATP
Younghoon Kim et al.
MOLECULAR CELL (2016)
Overcoming cetuximab resistance in Ewing's sarcoma by inhibiting lactate dehydrogenase-A
Jiaxin Fu et al.
MOLECULAR MEDICINE REPORTS (2016)
Prions and Protein Assemblies that Convey Biological Information in Health and Disease
David W. Sanders et al.
NEURON (2016)
Band 3 Erythrocyte Membrane Protein Acts as Redox Stress Sensor Leading to Its Phosphorylation by p(72) Syk
Antonella Pantaleo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Oxygen produced by cyanobacteria in simulated Archaean conditions partly oxidizes ferrous iron but mostly escapes-conclusions about early evolution
Susanne Rantamaki et al.
PHOTOSYNTHESIS RESEARCH (2016)
H2O2-Induced Oxidative Stress Affects SO4 = Transport in Human Erythrocytes
Rossana Morabito et al.
PLOS ONE (2016)
17-DMAG, an HSP90 Inhibitor, Ameliorates Multiple Organ Dysfunction Syndrome via Induction of HSP70 in Endotoxemic Rats
Yi-Li Wang et al.
PLOS ONE (2016)
Single Molecule Studies of the Diffusion of Band 3 in Sickle Cell Erythrocytes
Jeff Spector et al.
PLOS ONE (2016)
Disordered nucleiome: Abundance of intrinsic disorder in the DNA- and RNA-binding proteins in 1121 species from Eukaryota, Bacteria and Archaea
Chen Wang et al.
PROTEOMICS (2016)
Phase separation of signaling molecules promotes T cell receptor signal transduction
Xiaolei Su et al.
SCIENCE (2016)
Interaction between Prion Protein's Copper-Bound Octarepeat Domain and a Charged C-Terminal Pocket Suggests a Mechanism for N-Terminal Regulation
Eric G. B. Evans et al.
STRUCTURE (2016)
The Role of Functional Prion-Like Proteins in the Persistence of Memory
Kausik Si et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells
Yong-Seok Han et al.
CELL DEATH & DISEASE (2016)
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells
Alessandro Corsaro et al.
ONCOTARGET (2016)
Glucose-based microbial production of the hormone melatonin in yeast Saccharomyces cerevisiae
Susanne M. Germann et al.
BIOTECHNOLOGY JOURNAL (2016)
A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy
Matthias Christoph Munder et al.
ELIFE (2016)
Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy
Wanyin Chen et al.
STEM CELLS INTERNATIONAL (2016)
Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase-1
Tigist Kassa et al.
FEBS OPEN BIO (2016)
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution
Lisa Gasperini et al.
FRONTIERS IN NEUROSCIENCE (2016)
Copper-induced structural conversion templates prion protein oligomerization and neurotoxicity
Chi-Fu Yen et al.
SCIENCE ADVANCES (2016)
Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte's Quality under in Vitro Conditions
Changjiu He et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Protoporphyrin IX: the Good, the Bad, and the Ugly
Madhav Sachar et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Adaptive Stress Responses During Tumor Metastasis and Dormancy
Daniela Senft et al.
TRENDS IN CANCER (2016)
Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis
Kirsten L. Viola et al.
ACTA NEUROPATHOLOGICA (2015)
The organization of melatonin in lipid membranes
Hannah Dies et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Intracellular pH imaging in cancer cells in vitro and tumors in vivo using the new genetically encoded sensor SypHer2
Marina V. Shirmanova et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)
A Central Role for Heme Iron in Colon Carcinogenesis Associated with Red Meat Intake
Nadia M. Bastide et al.
CANCER RESEARCH (2015)
SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer
Thomas T. Vellinga et al.
CLINICAL CANCER RESEARCH (2015)
Prion Protein Promotes Kidney Iron Uptake via Its Ferrireductase Activity
Swati Haldar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Breast cancer cells: Modulation by melatonin and the ubiquitin-proteasome system - A review
Jerry Vriend et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)
Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism
Dun-Xian Tan et al.
MOLECULES (2015)
Fyn is an important molecule in cancer pathogenesis and drug resistance
Daniel Elias et al.
PHARMACOLOGICAL RESEARCH (2015)
A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells
Anna-Maria Barciszewska et al.
PLOS ONE (2015)
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
Shana Elbaum-Garfinkle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cellular and Molecular Mechanisms Underlying Oxygen-Dependent Radiosensitivity
Chao Liu et al.
RADIATION RESEARCH (2015)
pH Gradient Reversal: An Emerging Hallmark of Cancers
Mohit Sharma et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2015)
Effects of heme-PrP complex on cell-free conversion and peroxidase-linked immunodetection of prions in blood-based assays
Andrei Soutyrine et al.
RESEARCH IN VETERINARY SCIENCE (2015)
Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis
Cornelius Kwang-Lee Chieng et al.
TUMOR BIOLOGY (2015)
The prion protein constitutively controls neuronal store-operated Ca2+ entry through Fyn kinase
Agnese De Mario et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits
Corti Denise et al.
ONCOTARGET (2015)
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules
Sonja Kroschwald et al.
ELIFE (2015)
Role of Heme in Cardiovascular Physiology and Disease
Konrad Teodor Sawicki et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2015)
EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care
Simon Finnegan et al.
ADVANCES IN WOUND CARE (2015)
Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life
Zhenling Peng et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Dietary Iron Controls Circadian Hepatic Glucose Metabolism Through Heme Synthesis
Judith A. Simcox et al.
DIABETES (2015)
Melatonin compensates silencing of heat shock protein 70 and suppresses ultraviolet radiation-induced inflammation in human skin ex vivo and cultured keratinocytes
Konrad Kleszczynski et al.
JOURNAL OF PINEAL RESEARCH (2015)
Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis
Annia Galano et al.
JOURNAL OF PINEAL RESEARCH (2015)
Liquid-Liquid Phase Separation in Biology
Anthony A. Hyman et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30 (2014)
Membrane-Bound CYB5R3 Is a Common Effector of Nutritional and Oxidative Stress Response Through FOXO3a and Nrf2
Emilio Siendones et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Copper: toxicological relevance and mechanisms
Lisa M. Gaetke et al.
ARCHIVES OF TOXICOLOGY (2014)
Reactive oxygen species at phospholipid bilayers: Distribution, mobility and permeation
Rodrigo M. Cordeiro
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
Erythocyte Membrane Model with Explicit Description of the Lipid Bilayer and the Spectrin Network
He Li et al.
BIOPHYSICAL JOURNAL (2014)
Structural and Dynamic Properties of the Human Prion Protein
Wei Chen et al.
BIOPHYSICAL JOURNAL (2014)
New insights provided by a comparison of impaired deformability with erythrocyte oxidative stress for sickle cell disease
Viachaslau M. Barodka et al.
BLOOD CELLS MOLECULES AND DISEASES (2014)
Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells
Yanrong Qian et al.
CANCER LETTERS (2014)
Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
Xin Cai et al.
CELL (2014)
Rebels with a cause: molecular features and physiological consequences of yeast prions
David M. Garcia et al.
FEMS YEAST RESEARCH (2014)
Inborn defects in the antioxidant systems of human red blood cells
Rob van Zwieten et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Sporadic Distribution of Prion-Forming Ability of Sup35p from Yeasts and Fungi
Herman K. Edskes et al.
GENETICS (2014)
Regulation of Aggregation Behavior and Neurotoxicity of Prion Neuropeptides by Platinum Complexes
Xuesong Wang et al.
INORGANIC CHEMISTRY (2014)
A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein
Alex J. McDonald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Calcium regulation of neural rhythms, memory and Alzheimer's disease
Michael J. Berridge
JOURNAL OF PHYSIOLOGY-LONDON (2014)
Melatonin synthesis in rice seedlings in vivo is enhanced at high temperatures and under dark conditions due to increased serotonin N-acetyltransferase and N-acetylserotonin methyltransferase activities
Yeong Byeon et al.
JOURNAL OF PINEAL RESEARCH (2014)
Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cells
Sara Proietti et al.
JOURNAL OF PINEAL RESEARCH (2014)
A review of metal-catalyzed molecular damage: protection by melatonin
Alejandro Romero et al.
JOURNAL OF PINEAL RESEARCH (2014)
Probing the N-Terminal β-Sheet Conversion in the Crystal Structure of the Human Prion Protein Bound to a Nanobody
Romany N. N. Abskharon et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics
Linn Fagerberg et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance
Hariharan Easwaran et al.
MOLECULAR CELL (2014)
Membrane rafts of the human red blood cell
Annarita Ciana et al.
MOLECULAR MEMBRANE BIOLOGY (2014)
Correction: The Cellular Prion Protein PrPc Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins
Etienne Morel et al.
PLoS One (2014)
Correction: Prion Protein Modulates Cellular Iron Uptake: A Novel Function with Implications for Prion Disease Pathogenesis
Ajay Singh et al.
PLoS One (2014)
The Interaction between Amyloid-βPeptides and Anionic Lipid Membranes Containing Cholesterol and Melatonin
Hannah Dies et al.
PLOS ONE (2014)
Role of pHi, and proton transporters in oncogene-driven neoplastic transformation
Stephan Joel Reshkin et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
The cellular form of the prion protein guides the differentiation of human embryonic stem cells into neuron-, oligodendrocyte-, and astrocyte-committed lineages
Young Jin Lee et al.
PRION (2014)
PrP overdrive Does inhibition of α-cleavage contribute to PrPC toxicity and prion disease?
Alex J. McDonald et al.
PRION (2014)
Hsp70-a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck
Mathias Gehrmann et al.
RADIATION ONCOLOGY (2014)
Nucleic acid induced unfolding of recombinant prion protein globular fragment is pH dependent
Alakesh Bera et al.
PROTEIN SCIENCE (2014)
Melatonin directly interacts with cholesterol and alleviates cholesterol effects in dipalmitoylphosphatidylcholine monolayers
Youngjik Choi et al.
SOFT MATTER (2014)
Prion-like aggregation of mutant p53 in cancer
Jerson L. Silva et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment
Daniel Ackerman et al.
TRENDS IN CELL BIOLOGY (2014)
The Structure of Human Prions: From Biology to Structural Models - Considerations and Pitfalls
Claudia Y. Acevedo-Morantes et al.
VIRUSES-BASEL (2014)
Multidrug resistance protein l localization lipid raft domains and prostasomes in prostate cancer cell lines
Alba Goma et al.
ONCOTARGETS AND THERAPY (2014)
Heme, an Essential Nutrient from Dietary Proteins, Critically Impacts Diverse Physiological and Pathological Processes
Jagmohan Hooda et al.
NUTRIENTS (2014)
Cholesterol level affects surface charge of lipid membranes in saline solution
Aniket Magarkar et al.
SCIENTIFIC REPORTS (2014)
Red blood cell oxidative stress impairs oxygen delivery and induces red blood cell aging
Joy G. Mohanty et al.
FRONTIERS IN PHYSIOLOGY (2014)
PrP(C) from stem cells to cancer
Severine Martin-Lanneree et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2014)
Prion Protein Expression and Functional Importance in Developmental Angiogenesis: Role in Oxidative Stress and Copper Homeostasis
Nadia Alfaidy et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Hemoglobin Redox Reactions and Red Blood Cell Aging
Joseph M. Rifkind et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte membrane
Marko Stefanovic et al.
BIOCHEMICAL JOURNAL (2013)
Lipid raft modulation by Rp1 reverses multidrug resistance via inactivating MDR-1 and Src inhibition
Un-Jung Yun et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Amyloids and Yeast Prion Biology
Reed B. Wickner et al.
BIOCHEMISTRY (2013)
Effect of melatonin and cholesterol on the structure of DOPC and DPPC membranes
E. Drolle et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Acidic extracellular microenvironment and cancer
Yasumasa Kato et al.
CANCER CELL INTERNATIONAL (2013)
CD44-Positive Cancer Stem Cells Expressing Cellular Prion Protein Contribute to Metastatic Capacity in Colorectal Cancer
Lei Du et al.
CANCER RESEARCH (2013)
Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Veronica Estrella et al.
CANCER RESEARCH (2013)
Significance of Prion and Prion-Like Proteins in Cancer Development, Progression and Multi-Drug Resistance
Caroline Hinton et al.
CURRENT CANCER DRUG TARGETS (2013)
Changes in prion replication environment cause prion strain mutation
Nuria Gonzalez-Montalban et al.
FASEB JOURNAL (2013)
Heme Bound Amylin: Spectroscopic Characterization, Reactivity, and Relevance to Type 2 Diabetes
Soumya Mukherjee et al.
INORGANIC CHEMISTRY (2013)
Melatonin Anticancer Effects: Review
Giuseppe Di Bella et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Prion Protein Regulates Iron Transport by Functioning as a Ferrireductase
Ajay Singh et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
The cellular form of the prion protein is involved in controlling cell cycle dynamics, self-renewal, and the fate of human embryonic stem cell differentiation
Young Jin Lee et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2′-deoxyguanosine) in ex vivo human skin
Tobias W. Fischer et al.
JOURNAL OF PINEAL RESEARCH (2013)
Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes
Dun-Xian Tan et al.
JOURNAL OF PINEAL RESEARCH (2013)
Growth conditions determine different melatonin levels in Lupinus albus L.
Marino B. Arnao et al.
JOURNAL OF PINEAL RESEARCH (2013)
Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
Ji Won Um et al.
NEURON (2013)
Enhanced Heme Function and Mitochondrial Respiration Promote the Progression of Lung Cancer Cells
Jagmohan Hooda et al.
PLOS ONE (2013)
The Observation of Highly Ordered Domains in Membranes with Cholesterol
Clare L. Armstrong et al.
PLOS ONE (2013)
The role of prion protein in stem cell regulation
A. Miranda et al.
REPRODUCTION (2013)
Blessings in disguise: biological benefits of prion-like mechanisms
Gregory A. Newby et al.
TRENDS IN CELL BIOLOGY (2013)
Archaeal and bacterial diversity in an arsenic-rich shallow-sea hydrothermal system undergoing phase separation
Roy E. Price et al.
FRONTIERS IN MICROBIOLOGY (2013)
Pluripotency transcription factors and cancer stem cells: small genes make a big difference
Anfei Liu et al.
CHINESE JOURNAL OF CANCER (2013)
pH sensing and regulation in cancer
Mehdi Damaghi et al.
FRONTIERS IN PHYSIOLOGY (2013)
Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer
Marc-Andre Dery et al.
BREAST CANCER RESEARCH (2013)
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
Gregory LaMonte et al.
CANCER & METABOLISM (2013)
The Ubiquity of Iron
Perry A. Frey et al.
ACS CHEMICAL BIOLOGY (2012)
Identification of Contact Sites between Ankyrin and Band 3 in the Human Erythrocyte Membrane
Jesse L. Grey et al.
BIOCHEMISTRY (2012)
Potential roles for prions and protein-only inheritance in cancer
H. Antony et al.
CANCER AND METASTASIS REVIEWS (2012)
The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials
Ye-min Wang et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2012)
Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
Mayumi Tamada et al.
CANCER RESEARCH (2012)
Phosphorylation as a Tool To Modulate Aggregation Propensity and To Predict Fibril Architecture
Nathalie M. Valette et al.
CHEMBIOCHEM (2012)
TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells
Dongxiao Zhuang et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Soluble Prion Protein Inhibits Amyloid-β (Aβ) Fibrillization and Toxicity
Krzysztof Nieznanski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life
Bin Xue et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2012)
Octarepeat peptides of prion are essential for multidrug resistance in gastric cancer cells
Ji Heng Wang et al.
JOURNAL OF DIGESTIVE DISEASES (2012)
Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations
Carmen Venegas et al.
JOURNAL OF PINEAL RESEARCH (2012)
Phase transitions in the assembly of multivalent signalling proteins
Pilong Li et al.
NATURE (2012)
Prions are a common mechanism for phenotypic inheritance in wild yeasts
Randal Halfmann et al.
NATURE (2012)
PERSPECTIVE Prion propagation, toxicity and degradation
Adriano Aguzzi et al.
NATURE NEUROSCIENCE (2012)
Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation
R. Santoro et al.
ONCOGENE (2012)
Cellular prion protein accelerates colorectal cancer metastasis via the Fyn-SP1-SATB1 axis
Qianwei Wang et al.
ONCOLOGY REPORTS (2012)
Kosmotropic Anions Promote Conversion of Recombinant Prion Protein into a PrPSc-Like Misfolded Form
Rodrigo Diaz-Espinoza et al.
PLOS ONE (2012)
α-Cleavage of cellular prion protein
Jingjing Liang et al.
PRION (2012)
A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress
Genjiro Suzuki et al.
SCIENCE (2012)
The Origins of the RNA World
Michael P. Robertson et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Propagation of RML Prions in Mice Expressing PrP Devoid of GPI Anchor Leads to Formation of a Novel, Stable Prion Strain
Sukhvir Paul Mahal et al.
PLOS PATHOGENS (2012)
The effect of acute swimming exercise on plasma melatonin levels in rats
A. Uzun et al.
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY (2012)
Modeling cancer glycolysis
Alvaro Marin-Hernandez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2011)
Regulation of membrane-cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3
Emanuela Ferru et al.
BLOOD (2011)
Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning
Lara Milane et al.
CANCER CELL INTERNATIONAL (2011)
Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells
Yeannie Hui-Yeng Yap et al.
CANCER LETTERS (2011)
Cellular prion protein promotes glucose uptake through the Fyn-HIF-2α-Glut1 pathway to support colorectal cancer cell survival
Qing-Quan Li et al.
CANCER SCIENCE (2011)
Expression and knockdown of cellular prion protein (PrPC) in differentiating mouse embryonic stem cells
Oscar A. Peralta et al.
DIFFERENTIATION (2011)
Cellular prion protein localizes to the nucleus of endocrine and neuronal cells and interacts with structural chromatin components
Alexander Strom et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2011)
The role of lipid rafts in prion protein biology
Victoria Lewis et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2011)
Prion-Forming Ability of Ure2 of Yeasts Is Not Evolutionarily Conserved
Herman K. Edskes et al.
GENETICS (2011)
Copper Alters Aggregation Behavior of Prion Protein and Induces Novel Interactions between Its N- and C-terminal Regions
Abhay Kumar Thakur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
A Naturally Occurring C-terminal Fragment of the Prion Protein (PrP) Delays Disease and Acts as a Dominant-negative Inhibitor of PrPSc Formation
Laura Westergard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
A mutation within the C-terminal domain of Sup35p that affects [PSI+] prion propagation
Mehdi Kabani et al.
MOLECULAR MICROBIOLOGY (2011)
Prion protein expression level alters regional copper, iron and zinc content in the mouse brain
M. Jake Pushie et al.
METALLOMICS (2011)
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
Clifford P. Brangwynne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Underestimation of the expression of cellular prion protein on human red blood cells
Martin Panigaj et al.
TRANSFUSION (2011)
Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine
Jonghwan Kim et al.
GENOME MEDICINE (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
Dysregulated pH: a perfect storm for cancer progression
Bradley A. Webb et al.
NATURE REVIEWS CANCER (2011)
Mitochondrial F1Fo-ATP synthase translocates to cell surface in hepatocytes and has high activity in tumor-like acidic and hypoxic environment
Zhan Ma et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2010)
Doppel and PrPC co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells
Anna Caputo et al.
BIOCHEMICAL JOURNAL (2010)
Influence of pH on the Human Prion Protein: Insights into the Early Steps of Misfolding
Marc W. van der Kamp et al.
BIOPHYSICAL JOURNAL (2010)
Band 3 multiprotein complexes in the red cell membrane; of mice and men
Emile van den Akker et al.
BLOOD CELLS MOLECULES AND DISEASES (2010)
Archaic chaos: intrinsically disordered proteins in Archaea
Bin Xue et al.
BMC SYSTEMS BIOLOGY (2010)
Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
Elizabeth C. Finger et al.
CANCER AND METASTASIS REVIEWS (2010)
Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized
Elsa Quintana et al.
CANCER CELL (2010)
Prion protein: From physiology to cancer biology
Maryam Mehrpour et al.
CANCER LETTERS (2010)
Interactions of Prion Protein With Intracellular Proteins: So Many Partners and no Consequences?
Krzysztof Nieznanski
CELLULAR AND MOLECULAR NEUROBIOLOGY (2010)
Prion Protein Amyloid Formation Involves Structural Rearrangements in the C-Terminal Domain
Jitendra Kumar et al.
CHEMBIOCHEM (2010)
Basic Mechanisms Involved in the Anti-Cancer Effects of Melatonin
M. D. Mediavilla et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Clinical Uses of Melatonin: Evaluation of Human Trials
E. J. Sanchez-Barcelo et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Biopreservation of red blood cells - the struggle with hemoglobin oxidation
Tamir Kanias et al.
FEBS JOURNAL (2010)
Electrode potentials of partially reduced oxygen species, from dioxygen to water
Willem H. Koppenol et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Lipid rafts and clusters of apoptotic signaling molecule-enriched rafts in cancer therapy
Faustino Mollinedo et al.
FUTURE ONCOLOGY (2010)
Prevention of UVB Radiation-induced Epidermal Damage by Expression of Heat Shock Protein 70
Minoru Matsuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain
Martin P. Boland et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
Johanna Chiche et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Lipid rafts play an important role for maintenance of embryonic stem cell self-renewal
Min Young Lee et al.
JOURNAL OF LIPID RESEARCH (2010)
Effect of Cholesterol on Electrostatics in Lipid-Protein Films of a Pulmonary Surfactant
Eric Finot et al.
LANGMUIR (2010)
Axonal prion protein is required for peripheral myelin maintenance
Juliane Bremer et al.
NATURE NEUROSCIENCE (2010)
Sensors and regulators of intracellular pH
Joseph R. Casey et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
The prion hypothesis: from biological anomaly to basic regulatory mechanism
Mick F. Tuite et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5
Marianne Renner et al.
NEURON (2010)
Prion disease susceptibility is affected by β-structure folding propensity and local side-chain interactions in PrP
M. Qasim Khan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Hofmeister effect on amyloid formation using yeast prion protein
Victor Yeh et al.
PROTEIN SCIENCE (2010)
Prions, protein homeostasis, and phenotypic diversity
Randal Halfmann et al.
TRENDS IN CELL BIOLOGY (2010)
Genomic polymorphisms in sickle cell disease: implications for clinical diversity and treatment
Kleber Yotsumoto Fertrin et al.
EXPERT REVIEW OF HEMATOLOGY (2010)
Role of Oct4 in maintaining and regaining stem cell pluripotency
Guilai Shi et al.
STEM CELL RESEARCH & THERAPY (2010)
An overview about erythrocyte membrane
Sofia de Oliveira et al.
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION (2010)
Determination of ultrafiltrable and exchangeable copper in plasma: stability and reference values in healthy subjects
Souleiman El Balkhi et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2009)
A large ribonucleoprotein particle induced by cytoplasmic PrP shares striking similarities with the chromatoid body, an RNA granule predicted to function in posttranscriptional gene regulation
Simon Beaudoin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
The role of copper in drug-resistant murine and human tumors
S. Majumder et al.
BIOMETALS (2009)
Effects of Lipid Composition and Phase on the Membrane Interaction of the Prion Peptide 106-126 Amide
Jian Zhong et al.
BIOPHYSICAL JOURNAL (2009)
Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
Johanna Chiche et al.
CANCER RESEARCH (2009)
The role of P-glycoprotein/cellular prion protein interaction in multidrug-resistant breast cancer cells treated with paclitaxel
Q. -Q. Li et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis
S. Zraika et al.
DIABETOLOGIA (2009)
Inhibition of PI3K/Akt partially leads to the inhibition of PrPC-induced drug resistance in gastric cancer cells
Jie Liang et al.
FEBS JOURNAL (2009)
UV-light-induced conversion and aggregation of prion proteins
Lars Redecke et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
ATM-mediated Transcriptional Elevation of Prion in Response to Copper-induced Oxidative Stress
Kefeng Qin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response
Cathryn L. Haigh et al.
JOURNAL OF CELL SCIENCE (2009)
Increased Proportions of C1 Truncated Prion Protein Protect Against Cellular M1000 Prion Infection
Victoria Lewis et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane
Alejandro K. Samhan-Arias et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
Molecular mechanisms for protein-encoded inheritance
Jed J. W. Wiltzius et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Self-Propagating β-Sheet Polypeptide Structures as Prebiotic Informational Molecular Entities: The Amyloid World
C. P. J. Maury
ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES (2009)
Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport
Ajay Singh et al.
PLOS ONE (2009)
Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
Vadivel Ganapathy et al.
PHARMACOLOGY & THERAPEUTICS (2009)
Role of band 3 in regulating metabolic flux of red blood cells
Ian A. Lewis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation
Carin Thomas et al.
REDOX REPORT (2009)
Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke
Stephen R. Robinson et al.
REDOX REPORT (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Regulation of Embryonic Cell Adhesion by the Prion Protein
Edward Malaga-Trillo et al.
PLOS BIOLOGY (2009)
Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders
Ajay Singh et al.
PLOS PATHOGENS (2009)
Glypican-1 Mediates Both Prion Protein Lipid Raft Association and Disease Isoform Formation
David R. Taylor et al.
PLOS PATHOGENS (2009)
Historical Survey on Chromatoid Body Research
Sadaki Yokota
ACTA HISTOCHEMICA ET CYTOCHEMICA (2008)
Effect of melatonin on the blood oxygen transport during hypothermia and rewarming in rats
S. Hlutkin et al.
ADVANCES IN MEDICAL SCIENCES (2008)
Expression of Heat Shock Protein 70 in Human Skin Cells as a Photoprotective Function after UV Exposure
Young Hwa Roh et al.
ANNALS OF DERMATOLOGY (2008)
A monoclonal antibody (1D12) defines novel distribution patterns of prion protein (PrP) as granules in nucleus
Tomoko Hosokawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Mechanism of the metal-mediated endocytosis of the prion protein
Nigel M. Hooper et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Prion protein aggresomes are poly(A)+ ribonucleoprotein complexes that induce a PKR-mediated deficient cell stress response
Kevin Goggin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Characterization of the deoxyhemoglobin binding site on human erythrocyte band 3:: implications for O2 regulation of erythrocyte properties
Haiyan Chu et al.
BLOOD (2008)
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice
M. Estela Campanella et al.
BLOOD (2008)
Glucose metabolism is accelerated by exposure to t-butylhydroperoxide during NADH consumption in human erythrocytes
Yuki Ogasawara et al.
BLOOD CELLS MOLECULES AND DISEASES (2008)
Free radical metabolism in human erythrocytes
M. Y. Burak Cimen
CLINICA CHIMICA ACTA (2008)
Hemin-induced necroptosis involves glutathione depletion in mouse astrocytes
Melissa D. Laird et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells
Mariana P. B. Gomes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Comparative Genomic Analyses of Copper Transporters and Cuproproteomes Reveal Evolutionary Dynamics of Copper Utilization and Its Link to Oxygen
Perry G. Ridge et al.
PLOS ONE (2008)
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain
Mark Wells et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hypoxia, DNA repair and genetic instability
Robert G. Bristow et al.
NATURE REVIEWS CANCER (2008)
Effect of lipid peroxidation on the properties of lipid bilayers: A molecular dynamics study
Jirasak Wong-Ekkabut et al.
BIOPHYSICAL JOURNAL (2007)
Hemin interactions and alterations of the subcellular localization of prion protein
Kil S. Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
pH dependence of melanoma cell migration:: protons extruded by NHE1 dominate protons of the bulk solution
Laura Stuewe et al.
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