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INTEGRATIVE BIOLOGY (2015)
Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer
Freya A. Goumas et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Radiation-induced fibrosis: mechanisms and implications for therapy
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JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2015)
Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
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JOURNAL OF CLINICAL INVESTIGATION (2015)
Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages
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JOURNAL OF CLINICAL INVESTIGATION (2015)
Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously
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JOURNAL OF CONTROLLED RELEASE (2015)
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis
Charles K. Pallangyo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Low numbers of tryptase+ and chymase+ mast cells associated with reduced survival and advanced tumor stage in melanoma
Hanna Siiskonen et al.
MELANOMA RESEARCH (2015)
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
Kari R. Fischer et al.
NATURE (2015)
Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
Richard A. Moffitt et al.
NATURE GENETICS (2015)
T cell exclusion, immune privilege, and the tumor microenvironment
Johanna A. Joyce et al.
SCIENCE (2015)
Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
Jean Albrengues et al.
NATURE COMMUNICATIONS (2015)
Tenascin-C: Exploitation and collateral damage in cancer management
Caroline Spenle et al.
CELL ADHESION & MIGRATION (2015)
Curcumin combined with FAPac vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma
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ONCOTARGET (2015)
Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts
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CELL REPORTS (2015)
CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function
Eunyoung Chun et al.
CELL REPORTS (2015)
Cancer associated fibroblasts have phenotypic and functional characteristics similar to the fibrocytes that represent a novel MDSC subset
Gurcan Gunaydin et al.
ONCOIMMUNOLOGY (2015)
Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
Kazuyoshi Shiga et al.
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Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study
Richard J. Kovacs et al.
CARDIOVASCULAR TOXICOLOGY (2015)
Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer
C. E. Weber et al.
ONCOGENE (2015)
A whole-cell tumor vaccine modified to express fibroblast activation protein induces antitumor immunity against both tumor cells and cancer-associated fibroblasts
Meihua Chen et al.
SCIENTIFIC REPORTS (2015)
Immunological hallmarks of stromal cells in the tumour microenvironment
Shannon J. Turley et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Hedgehog Signaling Restrains Bladder Cancer Progression by Eliciting Stromal Production of Urothelial Differentiation Factors
Kunyoo Shin et al.
CANCER CELL (2014)
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
Berna C. Oezdemir et al.
CANCER CELL (2014)
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Andrew D. Rhim et al.
CANCER CELL (2014)
The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
Ruth Scherz-Shouval et al.
CELL (2014)
Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer
Natalie Hartmann et al.
CLINICAL CANCER RESEARCH (2014)
IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells
Terry-Ann Curran et al.
IMMUNOBIOLOGY (2014)
A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment
Stuart J. Ellem et al.
JOURNAL OF PATHOLOGY (2014)
Insidious Changes in Stromal Matrix Fuel Cancer Progression
Fayth L. Miles et al.
MOLECULAR CANCER RESEARCH (2014)
Senescent stroma promotes prostate cancer progression: The role of miR-210
Maria Letizia Taddei et al.
MOLECULAR ONCOLOGY (2014)
Is there new hope for therapeutic matrix metalloproteinase inhibition?
Roosmarijn E. Vandenbroucke et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Interaction with colon cancer cells hyperactivates TGF-beta signaling in cancer-associated fibroblasts
L. J. A. C. Hawinkels et al.
ONCOGENE (2014)
Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression
G. Comito et al.
ONCOGENE (2014)
TGF-β-inducible microRNA-183 silences tumor-associated natural killer cells
Sarah S. Donatelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Pharmacokinetics and Toxicology of a Fibroblast Activation Protein (FAP)-Activated Prodrug in Murine Xenograft Models of Human Cancer
W. Nathaniel Brennen et al.
PROSTATE (2014)
Tranilast Inhibits the Function of Cancer-Associated Fibroblasts Responsible for the Induction of Immune Suppressor Cell Types
Y. Ohshio et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2014)
Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
Ubaldo E. Martinez-Outschoorn et al.
SEMINARS IN CANCER BIOLOGY (2014)
The role of reactive oxygen species and metabolism on cancer cells and their microenvironment
Ana Costa et al.
SEMINARS IN CANCER BIOLOGY (2014)
Regulation of the anti-tumour immune response by cancer-associated fibroblasts
James Harper et al.
SEMINARS IN CANCER BIOLOGY (2014)
The IL-6-STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression
Q. Zhu et al.
CELL DEATH & DISEASE (2014)
LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer
Jean Albrengues et al.
CELL REPORTS (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Hua Yu et al.
NATURE REVIEWS CANCER (2014)
Hypoxia and the extracellular matrix: drivers of tumour metastasis
Daniele M. Gilkes et al.
NATURE REVIEWS CANCER (2014)
GRP78 secreted by tumor cells stimulates differentiation of bone marrow mesenchymal stem cells to cancer-associated fibroblasts
Yanan Peng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer
Xiongyan Wu et al.
CANCER LETTERS (2013)
Docetaxel Conjugate Nanoparticles That Target α-Smooth Muscle Actin-Expressing Stromal Cells Suppress Breast Cancer Metastasis
Mami Murakami et al.
CANCER RESEARCH (2013)
Dynamic Mast Cell-Stromal Cell Interactions Promote Growth of Pancreatic Cancer
Ying Ma et al.
CANCER RESEARCH (2013)
Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
Thomas A. Mace et al.
CANCER RESEARCH (2013)
Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
Daniela Elena Costea et al.
CANCER RESEARCH (2013)
Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer
Ludivine Bochet et al.
CANCER RESEARCH (2013)
Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma
Tomonari Kinoshita et al.
CANCER SCIENCE (2013)
Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients
Mercedes Herrera et al.
CANCER SCIENCE (2013)
Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism Implications for breast cancer prevention
Rosa Sanchez-Alvarez et al.
CELL CYCLE (2013)
Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma
Abasi Ene-Obong et al.
GASTROENTEROLOGY (2013)
Hepatic stellate cells in liver development, regeneration, and cancer
Chunyue Yin et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
Edward W. Roberts et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
Eric Tran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells
Petra C. Schuberth et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
Pancreatic-carcinoma-cell-derived pro-angiogenic factors can induce endothelial-cell differentiation of a subset of circulating CD34+ progenitors
Barbara Vizio et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo et al.
NATURE CELL BIOLOGY (2013)
Microenvironmental regulation of tumor progression and metastasis
Daniela F. Quail et al.
NATURE MEDICINE (2013)
Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity
Tuanjie Li et al.
MEDICAL ONCOLOGY (2013)
Arginase II Expressed in Cancer-Associated Fibroblasts Indicates Tissue Hypoxia and Predicts Poor Outcome in Patients with Pancreatic Cancer
Yoshinori Ino et al.
PLOS ONE (2013)
A Vaccine That Co-Targets Tumor Cells and Cancer Associated Fibroblasts Results in Enhanced Antitumor Activity by Inducing Antigen Spreading
Stephen Gottschalk et al.
PLOS ONE (2013)
Lung Collagens Perpetuate Pulmonary Fibrosis via CD204 and M2 Macrophage Activation
Mirjam Stahl et al.
PLOS ONE (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Modulation of macrophage phenotype by cell shape
Frances Y. McWhorter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
Vikash P. Chauhan et al.
NATURE COMMUNICATIONS (2013)
Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis
Younghun Jung et al.
NATURE COMMUNICATIONS (2013)
Ways to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytes
Matteo Bellone et al.
FRONTIERS IN ONCOLOGY (2013)
Tracking cells in their native habitat: lineage tracing in epithelial neoplasia
Maria P. Alcolea et al.
NATURE REVIEWS CANCER (2013)
HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)
Ernestina Marianna De Francesco et al.
BREAST CANCER RESEARCH (2013)
History of myeloid-derived suppressor cells
James E. Talmadge et al.
NATURE REVIEWS CANCER (2013)
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Paolo P. Provenzano et al.
CANCER CELL (2012)
The roles of mast cells in anticancer immunity
Dyana K. Dalton et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
Tuanjie Li et al.
CANCER LETTERS (2012)
Tumor-associated neutrophils: friend or foe?
Zvi G. Fridlender et al.
CARCINOGENESIS (2012)
EMT and Dissemination Precede Pancreatic Tumor Formation
Andrew D. Rhim et al.
CELL (2012)
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth Connecting TGF-β signaling with Warburg-like cancer metabolism and L-lactate production
Carmela Guido et al.
CELL CYCLE (2012)
Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma
Jahan S. Khalili et al.
CLINICAL CANCER RESEARCH (2012)
On the dual roles and polarized phenotypes of neutrophils in tumor development and progression
H. Piccard et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2012)
Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin-1 and induction of poor prognosis factors
Jaroslav Valach et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
Helene Salmon et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Cancer-associated fibroblasts and CD163-positive macrophages in oral squamous cell carcinoma: their clinicopathological and prognostic significance
Nobuyuki Fujii et al.
JOURNAL OF ORAL PATHOLOGY & MEDICINE (2012)
Targeting Carcinoma-Associated Fibroblasts Within the Tumor Stroma With a Fibroblast Activation Protein-Activated Prodrug
W. Nathaniel Brennen et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2012)
Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature
Yuval Rinkevich et al.
NATURE CELL BIOLOGY (2012)
Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury
Sophie Dulauroy et al.
NATURE MEDICINE (2012)
Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils
Zvi G. Fridlender et al.
PLOS ONE (2012)
Cell Elasticity Determines Macrophage Function
Naimish R. Patel et al.
PLOS ONE (2012)
FSP1(+) Fibroblasts Promote Skin Carcinogenesis by Maintaining MCP-1-Mediated Macrophage Infiltration and Chronic Inflammation
Jinhua Zhang et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Mast cell: insight into remodeling a tumor microenvironment
Jing Liu et al.
CANCER AND METASTASIS REVIEWS (2011)
ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma
Victoria Sanz-Moreno et al.
CANCER CELL (2011)
Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
Michael Quante et al.
CANCER CELL (2011)
Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
Beatrice Dirat et al.
CANCER RESEARCH (2011)
Autocrine Transforming Growth Factor-β1 Promotes In Vivo Th17 Cell Differentiation
Ilona Gutcher et al.
IMMUNITY (2011)
In situ force mapping of mammary gland transformation
Jose I. Lopez et al.
INTEGRATIVE BIOLOGY (2011)
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
Lucia De Monte et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Lung Cancer-Derived Galectin-1 Mediates Dendritic Cell Anergy through Inhibitor of DNA Binding 3/IL-10 Signaling Pathway
Po-Lin Kuo et al.
JOURNAL OF IMMUNOLOGY (2011)
Serglycin: A Structural and Functional Chameleon with Wide Impact on Immune Cells
Svein O. Kolset et al.
JOURNAL OF IMMUNOLOGY (2011)
Natural Killer Cells and Solid Tumors
Ana Stojanovic et al.
JOURNAL OF INNATE IMMUNITY (2011)
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
Wei Tan et al.
NATURE (2011)
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
Bin-Zhi Qian et al.
NATURE (2011)
Molecular mechanisms and clinical applications of angiogenesis
Peter Carmeliet et al.
NATURE (2011)
Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
Benjamin Diop-Frimpong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors
Constantin Jotzu et al.
CELLULAR ONCOLOGY (2011)
Mast Cells Are Novel Independent Prognostic Markers in Prostate Cancer and Represent a Target for Therapy
Anna Johansson et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
Neta Erez et al.
CANCER CELL (2010)
Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts
Magdalena Ksiazkiewicz et al.
IMMUNOBIOLOGY (2010)
Neutrophils responsive to endogenous IFN-β regulate tumor angiogenesis and growth in a mouse tumor model
Jadwiga Jablonska et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures
Emeline Van Goethem et al.
JOURNAL OF IMMUNOLOGY (2010)
The Evolution of Extracellular Matrix
Suat Oezbek et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Dasatinib reverses Cancer-associated Fibroblasts (CAFs) from primary Lung Carcinomas to a Phenotype comparable to that of normal Fibroblasts
Silke Haubeiss et al.
MOLECULAR CANCER (2010)
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Yasushi Kojima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
The polarization of immune cells in the tumour environment by TGFβ
Richard A. Flavell et al.
NATURE REVIEWS IMMUNOLOGY (2010)
The impact of the extracellular matrix on inflammation
Lydia Sorokin
NATURE REVIEWS IMMUNOLOGY (2010)
Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma
Robert M. Eager et al.
BMC CANCER (2009)
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: N1 versus N2 TAN
Zvi G. Fridlender et al.
CANCER CELL (2009)
White Adipose Tissue Cells Are Recruited by Experimental Tumors and Promote Cancer Progression in Mouse Models
Yan Zhang et al.
CANCER RESEARCH (2009)
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Kandice R. Levental et al.
CELL (2009)
Identification of an active site of EMMPRIN for the augmentation of matrix metalloproteinase-1 and-3 expression in a co-culture of human uterine cervical carcinoma cells and fibroblasts
Takashi Sato et al.
GYNECOLOGIC ONCOLOGY (2009)
Tolerogenic dendritic cells in cancer, transplantation, and autoimmune diseases
Nicole Suciu-Foca et al.
HUMAN IMMUNOLOGY (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model
Debbie Liao et al.
PLOS ONE (2009)
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Mirna Balsamo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation
Gabriel A. Rabinovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Mast cells have prognostic value in Merkel cell carcinoma
Trevor W. Beer et al.
AMERICAN JOURNAL OF DERMATOPATHOLOGY (2008)
SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment
Bo Huang et al.
BLOOD (2008)
The role of endothelial-to-mesenchymal transition in cancer progression
S. Potenta et al.
BRITISH JOURNAL OF CANCER (2008)
Antibody-Mediated Delivery of Interleukin-2 to the Stroma of Breast Cancer Strongly Enhances the Potency of Chemotherapy
Jessica Marlind et al.
CLINICAL CANCER RESEARCH (2008)
Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts
Elinborg Ostermann et al.
CLINICAL CANCER RESEARCH (2008)
The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance
Paola Allavena et al.
IMMUNOLOGICAL REVIEWS (2008)
TGF-β utilizes SMAD3 to inhibit CD16-mediated IFN-γ production and antibody-dependent cellular cytotoxicity in human NK cells
Rossana Trotta et al.
JOURNAL OF IMMUNOLOGY (2008)
Progress in matrix metalloproteinase research
Gillian Murphy et al.
MOLECULAR ASPECTS OF MEDICINE (2008)
Cancer-related inflammation
Alberto Mantovani et al.
NATURE (2008)
A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression
Xiao-Tong Song et al.
NATURE MEDICINE (2008)
Cancer associated fibroblasts stimulated by transforming growth factor beta1 (TGF-β1) increase invasion rate of tumor cells:: a population study
Theresa M. Casey et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts
Elisabeth M. Zeisberg et al.
CANCER RESEARCH (2007)
Phase II trial of single agent Val-boroPro (Talabostat) inhibiting fibroblast activation protein in patients with metastatic colorectal cancer
Kalyani Narra et al.
CANCER BIOLOGY & THERAPY (2007)
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
Antoine E. Karnoub et al.
NATURE (2007)
Tumor microenvironment: The role of the tumor stroma in cancer
Hanchen Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associllited T cells
Michael R. Nazareth et al.
JOURNAL OF IMMUNOLOGY (2007)
The pancreatic stellate cell: a star on the rise in pancreatic diseases
M. Bishr Omary et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Histamine-mediated signaling processes in human malignant mammary cells
Vanina Medina et al.
CANCER BIOLOGY & THERAPY (2006)
Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity
Ryungsa Kim et al.
IMMUNOLOGY (2006)
Nf1± mast cells induce neurofibroma like phenotypes through secreted TGF-β signaling
Feng-Chun Yang et al.
HUMAN MOLECULAR GENETICS (2006)
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
Markus Loeffler et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Tumor-targeting properties of novel antibodies specific to the large isoform of tenascin-C
Simon S. Brack et al.
CLINICAL CANCER RESEARCH (2006)
TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
DA Thomas et al.
CANCER CELL (2005)
The chemokine system in diverse forms of macrophage activation and polarization
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
TJ Curiel et al.
NATURE MEDICINE (2003)
Human mast cells release metalloproteinase-9 on contact with activated T cells:: Juxtacrine regulation by TNF-α
D Baram et al.
JOURNAL OF IMMUNOLOGY (2001)
Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
B Elenbaas et al.
EXPERIMENTAL CELL RESEARCH (2001)