Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 22, Issue 6, Pages 884-903Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557521666211008153329
Keywords
Pyrimidine; heterocyclic compounds; marketed drugs; antimicrobial; anticancer; antiviral
Categories
Ask authors/readers for more resources
Pyrimidine and its derivatives are important heterocyclic compounds with wide applications in medicinal chemistry. Pyrimidine plays a significant role as an organic reaction intermediate and exhibits diverse biological activities such as antibacterial and anti-inflammatory effects. Various methods have been reported for the synthesis of pyrimidine derivatives.
Pyrimidine and its derivatives are a very important class of heterocyclic compounds that show interesting applications in the field of medicinal chemistry. Pyrimidine not only plays an important role as an organic reaction intermediate but also has a wide range of interesting biological activities viz. antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal activities, etc. Numerous methods are available for the formation of pyrimidine derivatives that have been reported in the literature. The advantage of pyrimidine as a starting material for different therapeutically potent derivatives has given momentum to this research. This review aims to report the new work on the synthesis of marketed drugs which consist pyrimidine moiety.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available