4.2 Article

Extended application of the rapid post-mortem test kit for bovine spongiform encephalopathy to chronic wasting disease

Journal

MICROBIOLOGY AND IMMUNOLOGY
Volume 66, Issue 5, Pages 212-215

Publisher

WILEY
DOI: 10.1111/1348-0421.12968

Keywords

Chronic wasting disease (CWD); prion; PRNP; rapid post-mortem test kit

Funding

  1. Development of Management Technologies for the Risk of Introduction of Livestock Infectious Diseases and Their Wildlife-borne Spreads in Japan [FY 2018-2022]
  2. Ministry of Agriculture, Forestry, and Fisheries of Japan [JPJ008617.18065101]

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The present study demonstrated that a rapid post-mortem test kit used for bovine spongiform encephalopathy surveillance in Japan is also valid for detecting chronic wasting disease (CWD) prion.
Chronic wasting disease (CWD) is a prion disease affecting cervid species primarily in the United States of America and Canada; however, it is now emerging in Scandinavian countries. Although CWD cases have not been reported in Japan, in case of a CWD outbreak occuring, it is critical to prepare for testing a large number of specimens. The present study showed that a rapid post-mortem test kit, which is used for bovine spongiform encephalopathy surveillance in Japan, is valid for the detection of CWD prion.

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