Journal
MICROBIAL CELL FACTORIES
Volume 20, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s12934-021-01702-3
Keywords
Whey protein hydrolysate; Casein hydrolysate; Bifidobacterium L80; Proliferation; Organic acid
Categories
Funding
- National Natural Science Foundation [32072258, 31871747]
- Major Science and technology Program of Heilongjiang [2020ZX08B02]
- Technological Innovation Specific Research Fund of Harbin Science and Technology Bureau [2016RAQXJ146]
- Harbin University of Commerce young innovative talents support program [2019CX06, 2019CX34, 2020CX26]
- Training plan of Young Innovative Talents in Universities of Heilongjiang [UNPYSCT-2020 218]
- 2020 Innovation Research Fund for Graduate Students Harbin University of Commerce [YJSCX2020-635HSD]
- Central financial support for the development of local colleges and Universities
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This study suggested that Milk Protein Hydrolysate could effectively enhance the proliferation of Bifidobacterium L80, increase viable counts, and improve antibacterial activity, contributing to the improvement of infant gut health.
The intestinal microecological environment is critical to an infant's growth. For those infants consuming milk power, it is very important to improve the intestinal microecological environment to promote the healthy growth of infants. In this paper, Milk protein hydrolysate (MPH), consisting of different proportions of proteins and small molecule peptides (5:5, 4:6, 3:7, 2:8, 1:9) were added to infant formula powder (IFP). The effects of MFP-enriched IFP addition on proliferation and metabolism of Bifidobacterium L80 were studied. Compared with MPH-free IFP, MFP-enriched IFP with 1:9 of proteins to small molecule peptides significantly enhanced the proliferation of Bifidobacterium L80, resulting in higher cell density, greater viable counts and higher titratable acidity. MFP-enriched IFP increased the content of seven organic acids and H2O2 in the system, and improved the antibacterial activity to E. coli BL21. This study suggested that MPH could be an effective addition to infant formula powder to promote the growth of Bifidobacterium, so to improve the intestinal health of infants.
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