4.2 Review

Research progress in the estimation of postmortem interval (PMI) using non-coding RNA (ncRNA) markers

Journal

MEDICINE SCIENCE AND THE LAW
Volume -, Issue -, Pages -

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/00258024211064404

Keywords

forensic science; forensic pathology; estimation of postmortem interval; non-coding RNA; review

Funding

  1. Shanghai Sailing Program [21YF1418800]
  2. Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science [KF1904]

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This review discusses the use of specific RNA molecules for estimating Postmortem interval (PMI), highlighting methods, existing challenges, and future trends in the field. It provides technical references for relevant studies and practices in the estimation of PMI using non-coding RNAs.
Postmortem interval (PMI) estimation has always been a crucial focus and challenging issue in forensic pathology. In recent years, specific RNA molecules and their variation have been used worldwide to estimate PMI. In this review, we summarize the methods used to detect non-coding RNAs (ncRNAs) for PMI estimation based on the literature, show the existing problems and development trends, and provide technical references for relevant studies and estimation practices.

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