4.7 Review

beta 3-Adrenoceptor, a novel player in the round-trip from neonatal diseases to cancer: Suggestive clues from embryo

Related references

Note: Only part of the references are listed.
Article Pediatrics

Infantile hemangiomas β3-adrenoceptor overexpression is associated with nonresponse to propranolol

Andrea Bassi et al.

Summary: The research found a significant increase in the expression of beta(3)-AR in hemangioma biopsies from patients nonresponsive to propranolol treatment. This suggests a possible role of beta(3)-AR in the pathogenesis of hemangiomas and a potential new therapeutic target.

PEDIATRIC RESEARCH (2022)

Review Biochemistry & Molecular Biology

Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments

Xiaoxu Wei et al.

Summary: Overall, the use of VM inhibitors in combination with conventional anti-angiogenesis treatments is a promising strategy for improving the effectiveness of targeted angiogenesis treatments; further, considering the importance of hypoxia in tumor invasion and metastasis, drugs targeting the hypoxia signaling pathway seem to achieve good results.

MOLECULAR CANCER (2021)

Review Pediatrics

Clinical Efficacy and Safety of Propranolol in the Prevention and Treatment of Retinopathy of Prematurity: A Meta-Analysis of Randomized Controlled Trials

Haibo B. Kong et al.

Summary: Orally administered propranolol appears to reduce the risk of disease progression and the need for additional treatments in pre-term newborns with retinopathy of prematurity (ROP), especially in stage 2 ROP of the second phase. However, it is associated with an increased risk of adverse events that require careful monitoring for safety concerns.

FRONTIERS IN PEDIATRICS (2021)

Article Pharmacology & Pharmacy

β 3 Adrenergic Receptor Stimulation Promotes Reperfusion in Ischemic Limbs in a Murine Diabetic Model

Kristen J. Bubb et al.

Summary: The study demonstrates that stimulating the beta(3) adrenergic receptor (beta(3)AR) can promote angiogenesis in limbs of patients with peripheral arterial disease, improving redox balance and enhancing angiogenesis.

FRONTIERS IN PHARMACOLOGY (2021)

Review Pediatrics

Mirabegron: Pediatric First Approval

Susan J. Keam

Summary: Mirabegron, developed by Astellas Pharma Inc., is a well-established treatment for overactive bladder in adults and has recently been investigated in pediatric patients with neurogenic detrusor overactivity. It has received its first approval in pediatric patients aged >= 3 years, with extended-release tablets for patients >= 35 kg and oral suspension for patients < 35 kg. The milestones in the development of mirabegron for NDO have led to this pediatric first approval.

PEDIATRIC DRUGS (2021)

Review Cell Biology

Insight into Hypoxia Stemness Control

Miriam Di Mattia et al.

Summary: This research highlights the impact of oxygen on stem cell stemness and multilineage differentiation, emphasizing the signaling mechanisms activated under low oxygen tension and how targeted strategies can be designed to enhance the therapeutic applications of stem cells in tissue engineering and regenerative medicine.

CELLS (2021)

Review Oncology

Stress and cancer: mechanisms, significance and future directions

Anabel Eckerling et al.

Summary: While preclinical studies show that stress can facilitate cancer progression, its impact on human cancer mortality remains inconclusive. This review discusses mechanisms identified in preclinical and clinical studies regarding stress-reducing interventions, and proposes strategies to overcome obstacles in clinical research.

NATURE REVIEWS CANCER (2021)

Article Biochemistry & Molecular Biology

β3-Adrenoreceptor Blockade Induces Stem Cells Differentiation in Melanoma Microenvironment

Maura Calvani et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Pharmacology & Pharmacy

Upregulation of β3-adrenoceptors-a general marker of and protective mechanism against hypoxia?

Massimo Dal Monte et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020)

Review Immunology

Lactic Acid: A Novel Signaling Molecule in Early Pregnancy?

Li-Na Ma et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Medicine, Research & Experimental

The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

Brian S. Finlin et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Immunology

Mechanisms of Fetal T Cell Tolerance and Immune Regulation

Elze Rackaityte et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Cell Biology

Hypoxia-Driven Immune Escape in the Tumor Microenvironment

Alyssa Vito et al.

CELLS (2020)

Article Biochemistry & Molecular Biology

beta 3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance

Maura Calvani et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Immunology

β3-Adrenoceptors as Putative Regulator of Immune Tolerance in Cancer and Pregnancy

Maura Calvani et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Cardiac & Cardiovascular Systems

Cardioprotective Effects of Beta3-Adrenergic Receptor (3-AR) Pre-, Per-, and Post-treatment in Ischemia-Reperfusion

Ruduwaan Salie et al.

CARDIOVASCULAR DRUGS AND THERAPY (2019)

Article Pharmacology & Pharmacy

β3-Adrenoceptor as a potential immuno-suppressor agent in melanoma

Maura Calvani et al.

BRITISH JOURNAL OF PHARMACOLOGY (2019)

Review Oncology

Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches

Karen G. de la Cruz-Lopez et al.

FRONTIERS IN ONCOLOGY (2019)

Article Biochemistry & Molecular Biology

Understanding Immune Tolerance of Cancer: Re-Purposing Insights from Fetal Allografts and Microbes

Megan B. Barnet et al.

BIOESSAYS (2018)

Article Peripheral Vascular Disease

Modulation of cardiac stem cell characteristics by metoprolol in hypertensive heart disease

Sherin Saheera et al.

HYPERTENSION RESEARCH (2018)

Article Biochemistry & Molecular Biology

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

Maria Maryanovich et al.

NATURE MEDICINE (2018)

Review Biochemistry & Molecular Biology

Exploring the links between cancer and placenta development

Vincenzo Costanzo et al.

OPEN BIOLOGY (2018)

Review Oncology

The hypoxic tumour microenvironment

Varvara Petrova et al.

ONCOGENESIS (2018)

Article Peripheral Vascular Disease

Cardiovascular safety of mirabegron: analysis of an integrated clinical trial database of patients with overactive bladder syndrome

William B. White et al.

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2018)

Article Cell Biology

beta 3-Adrenoreceptors Control Mitochondrial Dormancy Melanoma and Embryonic Stem Cells

Maura Calvani et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Article Multidisciplinary Sciences

The impact of rare variation on gene expression across tissues

Xin Li et al.

NATURE (2017)

Review Dermatology

Does hypoxia play a role in infantile hemangioma?

Sophie de Jong et al.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2016)

Review Cardiac & Cardiovascular Systems

Cardiac salvage by tweaking with beta-3-adrenergic receptors

Jean-Luc Balligand

CARDIOVASCULAR RESEARCH (2016)

Review Pharmacology & Pharmacy

Molecular mechanisms for tumour resistance to chemotherapy

Shu-Ting Pan et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Targeting Β-3 Adrenergic Receptors In The Heart-Selective Agonism And Β-Blockade

Alessandro Cannavo et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2016)

Article Obstetrics & Gynecology

Oral propranolol in early stages of retinopathy of prematurity

Aldo Bancalari et al.

JOURNAL OF PERINATAL MEDICINE (2016)

Review Biochemistry & Molecular Biology

The Warburg Effect: How Does it Benefit Cancer Cells?

Maria V. Liberti et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Medicine, Research & Experimental

Hypoxia sensing through β-adrenergic receptors

Hoi I. Cheong et al.

JCI INSIGHT (2016)

Review Biochemistry & Molecular Biology

Glutathione during embryonic development

Jason M. Hansen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)

Article Biochemistry & Molecular Biology

Warburg-like Glycolysis and Lactate Shuttle in Mouse Decidua during Early Pregnancy

Ru-Juan Zuo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Pharmacology & Pharmacy

Role of host β1-and β2-adrenergic receptors in a murine model of B16 melanoma: functional involvement of β3-adrenergic receptors

Federica Sereni et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2015)

Article Medicine, General & Internal

A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma

C. Leaute-Labreze et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Multidisciplinary Sciences

Tissue-based map of the human proteome

Mathias Uhlen et al.

SCIENCE (2015)

Article Ophthalmology

Protective Effects of β1/2 Adrenergic Receptor Deletion in a Model of Oxygen-Induced Retinopathy

Massimo Dal Monte et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)

Article Oncology

Mechanisms of Hypoxia-Mediated Immune Escape in Cancer

Ivraym B. Barsoum et al.

CANCER RESEARCH (2014)

Article Pharmacology & Pharmacy

β3-adrenergic receptor activity modulates melanoma cell proliferation and survival through nitric oxide signaling

Massimo Dal Monte et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2014)

Article Agriculture, Dairy & Animal Science

Expression of Adrenergic Receptors in Bovine and Rabbit Oocytes and Preimplantation Embryos

S. Cikos et al.

REPRODUCTION IN DOMESTIC ANIMALS (2014)

Article Ophthalmology

The β-adrenergic system as a possible new target for pharmacologic treatment of neovascular retinal diseases

Giovanni Casini et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2014)

Article Biochemistry & Molecular Biology

Parallels between embryo and cancer cell metabolism

Danielle G. Smith et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2013)

Article Obstetrics & Gynecology

The Biology of Retinopathy of Prematurity How Knowledge of Pathogenesis Guides Treatment

Lois E. Smith et al.

CLINICS IN PERINATOLOGY (2013)

Article Ophthalmology

Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice

Massimo Dal Monte et al.

EXPERIMENTAL EYE RESEARCH (2013)

Article Cardiac & Cardiovascular Systems

Anti-hypertrophic and anti-oxidant effect of beta3-adrenergic stimulation in myocytes requires differential neuronal NOS phosphorylation

Vabren L. Watts et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)

Article Genetics & Heredity

Functional involvement of β3-adrenergic receptors in melanoma growth and vascularization

Massimo Dal Monte et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2013)

Review Biochemistry & Molecular Biology

Fetomaternal immune cross-talk and its consequences for maternal and offspring's health

Petra C. Arck et al.

NATURE MEDICINE (2013)

Review Cell Biology

Role of Glutathione in Cancer Progression and Chemoresistance

Nicola Traverso et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Article Multidisciplinary Sciences

Autonomic Nerve Development Contributes to Prostate Cancer Progression

Claire Magnon et al.

SCIENCE (2013)

Review Obstetrics & Gynecology

The role of hyperoxia in the pathogenesis of experimental BPD

Bradley W. Buczynski et al.

SEMINARS IN PERINATOLOGY (2013)

Article Immunology

Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling

Donald M. Lamkin et al.

BRAIN BEHAVIOR AND IMMUNITY (2012)

Article Oncology

Molecular Pathways: Beta-Adrenergic Signaling in Cancer

Steven W. Cole et al.

CLINICAL CANCER RESEARCH (2012)

Article Cardiac & Cardiovascular Systems

Cardioprotective Effect of Beta-3 Adrenergic Receptor Agonism Role of Neuronal Nitric Oxide Synthase

Xiaolin Niu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)

Article Pathology

β-Adrenergic receptor expression in vascular tumors

Karen M. Chisholm et al.

MODERN PATHOLOGY (2012)

Article Biochemistry & Molecular Biology

Glycolysis in preimplantation development is partially controlled by the Warburg Effect

Bethany K. Redel et al.

MOLECULAR REPRODUCTION AND DEVELOPMENT (2012)

Article Biochemistry & Molecular Biology

A role for the Warburg effect in preimplantation embryo development: Metabolic modification to support rapid cell proliferation

Rebecca L. Krisher et al.

MOLECULAR REPRODUCTION AND DEVELOPMENT (2012)

Article Medicine, General & Internal

Cancer and Pregnancy: Parallels in Growth, Invasion, and Immune Modulation and Implications for Cancer Therapeutic Agents

Shernan G. Holtan et al.

MAYO CLINIC PROCEEDINGS (2012)

Review Obstetrics & Gynecology

Mechanisms for Ductus Arteriosus Closure

Flavio Coceani et al.

SEMINARS IN PERINATOLOGY (2012)

Article Ophthalmology

Beta-Adrenoreceptor Agonism Influences Retinal Responses to Hypoxia in a Model of Retinopathy of Prematurity

Massimo Dal Monte et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)

Article Immunology

Social isolation is associated with elevated tumor norepinephrine in ovarian carcinoma patients

Susan K. Lutgendorf et al.

BRAIN BEHAVIOR AND IMMUNITY (2011)

Article Biochemistry & Molecular Biology

Beta-3 agonist-induced lipolysis and nitric oxide production: relationship to PPARgamma agonist/antagonist and AMP kinase modulation

Jiri Hodis et al.

GENERAL PHYSIOLOGY AND BIOPHYSICS (2011)

Article Oncology

Beta Blockers and Breast Cancer Mortality: A Population-Based Study

Thomas I. Barron et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

Article Biochemistry & Molecular Biology

Antiangiogenic effects of β2-adrenergic receptor blockade in a mouse model of oxygen-induced retinopathy

Davide - Martini et al.

JOURNAL OF NEUROCHEMISTRY (2011)

Article Multidisciplinary Sciences

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells

Andrea Facciabene et al.

NATURE (2011)

Review Cell Biology

The relationship between early embryo development and tumourigenesis

Yanlei Ma et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)

Article Pharmacology & Pharmacy

Pharmacological evidence for the presence of functional β3-adrenoceptors in rat retinal blood vessels

Asami Mori et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2010)

Article Biochemistry & Molecular Biology

Role of VEGF in organogenesis

Jody J. Haigh

Organogenesis (2010)

Article Clinical Neurology

The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain

Regina Trollmann et al.

BRAIN & DEVELOPMENT (2009)

Review Cell Biology

Regulation of Angiogenesis by Oxygen and Metabolism

Peter Fraisl et al.

DEVELOPMENTAL CELL (2009)

Review Immunology

Human embryo immune escape mechanisms rediscovered by the tumor

Laura Ridolfi et al.

IMMUNOBIOLOGY (2009)

Article Pediatrics

Infantile Hemangiomas and Retinopathy of Prematurity: Possible Association

Vijayakumar Praveen et al.

PEDIATRICS (2009)

Review Multidisciplinary Sciences

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Matthew G. Vander Heiden et al.

SCIENCE (2009)

Review Biochemistry & Molecular Biology

Regulatory T cells and immune tolerance

Shimon Sakaguchi et al.

Letter Medicine, General & Internal

Propranolol for severe hemangiomas of infancy

Christine Leaute-Labreze et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Review Obstetrics & Gynecology

The neonatal intestinal vasculature: Contributing factors to necrotizing enterocolitis

Craig A. Nankervis et al.

SEMINARS IN PERINATOLOGY (2008)

Review Biochemistry & Molecular Biology

T-cell death and cancer immune tolerance

B. Lu et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Hematology

Hypoxia-induced mediators of stem/progenitor cell trafficking are increased in children with hemangioma

Mark E. Kleinman et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Article Obstetrics & Gynecology

Identification of functional α2- and β-adrenergic receptors in mammalian spermatozoa

Susan A. Adeoya-Osiguwa et al.

HUMAN REPRODUCTION (2006)

Article Immunology

Regulation of T cell responses in the developing human fetus

Jakob Michaelsson et al.

JOURNAL OF IMMUNOLOGY (2006)

Article Physiology

P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages

AA Mathias et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)

Article Biochemistry & Molecular Biology

Expression of beta adrenergic receptors in mouse oocytes and preimplantation embryos

S Cikos et al.

MOLECULAR REPRODUCTION AND DEVELOPMENT (2005)

Article Endocrinology & Metabolism

β3-adrenoceptor is the predominant β-adrenoceptor subtype in human myometrium and its expression is up-regulated in pregnancy

C Rouget et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Review Oncology

Molecular mechanisms of drug resistance

DB Longley et al.

JOURNAL OF PATHOLOGY (2005)

Article Nutrition & Dietetics

Glutathione metabolism and its implications for health

GY Wu et al.

JOURNAL OF NUTRITION (2004)

Article Pharmacology & Pharmacy

Comparative pharmacology of human β-adrenergic receptor subtypes -: characterization of stably transfected receptors in CHO cells

C Hoffmann et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)

Article Obstetrics & Gynecology

Impact of oxygen concentration on embryonic development of mouse zygotes

L Karagenc et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2004)

Article Biochemistry & Molecular Biology

Role of adrenergic receptor subtypes in the control of human placental blood vessels

BE Resch et al.

MOLECULAR REPRODUCTION AND DEVELOPMENT (2003)

Article Pharmacology & Pharmacy

Ontogenesis of β-adrenoceptor signaling:: Implications for perinatal physiology and for fetal effects of tocolytic drugs

TA Slotkin et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)

Article Biochemistry & Molecular Biology

β3-Adrenergic receptors regulate retinal endothelial cell migration and proliferation

JJ Steinle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Obstetrics & Gynecology

β2- and β3-adrenoreceptor agonists:: Human myometrial selectivity and effects on umbilical artery tone

MC Dennedy et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2002)

Review Oncology

Emerging molecular markers of cancer

D Sidransky

NATURE REVIEWS CANCER (2002)

Article Cardiac & Cardiovascular Systems

Upregulation of functional β3-adrenergic receptor in the failing canine myocardium

HJ Cheng et al.

CIRCULATION RESEARCH (2001)

Article Obstetrics & Gynecology

Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation

E Jauniaux et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2001)