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Adam Giangreco et al.
AGING CELL (2008)
Reproductive senescence in a long-lived seabird: Rates of decline in late-life performance are associated with varying costs of early reproduction
Thomas E. Reed et al.
AMERICAN NATURALIST (2008)
Stems cells and the pathways to aging and cancer
Derrick J. Rossi et al.
CELL (2008)
The longest telomeres: a general signature of adult stem cell compartments
Ignacio Flores et al.
GENES & DEVELOPMENT (2008)
Role of the GH/IGF-1 axis in lifespan and healthspan: Lessons from animal models
Darlene E. Berryman et al.
GROWTH HORMONE & IGF RESEARCH (2008)
Dynamics of fat cell turnover in humans
Kirsty L. Spalding et al.
NATURE (2008)
Quiet as a mouse: dissecting the molecular and genetic basis of hearing
Steve D. M. Brown et al.
NATURE REVIEWS GENETICS (2008)
Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies
A. Stolzing et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Sex differences in ageing in natural populations of vertebrates
T. H. Clutton-Brock et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2007)
Motif module map reveals enforcement of aging by continual NF-κB activity
Adam S. Adler et al.
GENES & DEVELOPMENT (2007)
Photoageing: mechanism, prevention and therapy
M. Yaar et al.
BRITISH JOURNAL OF DERMATOLOGY (2007)
Epidermal stem cells are resistant to cellular aging
Matthew M. Stern et al.
AGING CELL (2007)
A common variant on chromosome 9p21 affects the risk of myocardial infarction
Anna Helgadottir et al.
SCIENCE (2007)
Longevity among hunter-gatherers: A cross-cultural examination
Michael Gurven et al.
POPULATION AND DEVELOPMENT REVIEW (2007)
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
Joao F. Passos et al.
PLOS BIOLOGY (2007)
A common variant of the p16INK4a genetic region is associated with physical function in older people
David Melzer et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
A single IGF1 allele is a major determinant of small size in dogs
Nathan B. Sutter et al.
SCIENCE (2007)
Mitochondrial point mutations do not limit the natural lifespan of mice
Marc Vermulst et al.
NATURE GENETICS (2007)
Scaling of number, size, and metabolic rate of cells with body size in mammals
Van M. Savage et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention - Systematic review and meta-analysis
Goran Bjelakovic et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Age, experience and reproductive performance in a long-lived bird: a hormonal perspective
Frederic Angelier et al.
BEHAVIORAL ECOLOGY AND SOCIOBIOLOGY (2007)
Environmental variation and experience-related differences in the demography of the long-lived black-browed albatross
Marie Nevoux et al.
JOURNAL OF ANIMAL ECOLOGY (2007)
How stem cells age and why this makes us grow old
Norman E. Sharpless et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
NATURE (2006)
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
Akiko Takahashi et al.
NATURE CELL BIOLOGY (2006)
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
Viktor Janzen et al.
NATURE (2006)
Aging and immortality - Quasi-programmed senescence and its pharmacologic inhibition
Mikhail V. Blagosklonny
CELL CYCLE (2006)
Lymphomas and leukemias in mice
Jerrold M. Ward
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2006)
Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals - A randomized controlled trial
LK Heilbronn et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
K Ito et al.
NATURE MEDICINE (2006)
Prevalence of monoclonal gammopathy of undetermined significance
RA Kyle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age
DM Lloyd-Jones et al.
CIRCULATION (2006)
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission
LC Greaves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Mechanisms of therapy-related carcinogenesis
JM Allan et al.
NATURE REVIEWS CANCER (2005)
Opinion - Programmed and altruistic ageing
VD Longo et al.
NATURE REVIEWS GENETICS (2005)
Beyond the '3/4-power law': variation in the intra- and interspecific scaling of metabolic rate in animals
DS Glazier
BIOLOGICAL REVIEWS (2005)
p63 deficiency activates a program of cellular senescence and leads to accelerated aging
WM Keyes et al.
GENES & DEVELOPMENT (2005)
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
GC Kujoth et al.
SCIENCE (2005)
Cell intrinsic alterations underlie hematopoietic stem cell aging
DJ Rossi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance
RA Miller et al.
AGING CELL (2005)
Effects of caloric restriction on cell proliferation in several tissues in mice: role of intermittent feeding
EA Hsieh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
J Campisi
CELL (2005)
Understanding the odd science of aging
TBL Kirkwood
CELL (2005)
Overview of caloric restriction and ageing
EJ Masoro
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
M Murakami et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Accelerated telomere shortening in response to life stress
ES Epel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Shark cartilage, cancer and the growing threat of pseudoscience
GK Ostrander et al.
CANCER RESEARCH (2004)
Gene regulation and DNA damage in the ageing human brain
T Lu et al.
NATURE (2004)
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A Trifunovic et al.
NATURE (2004)
Tobacco carcinogens, their biomarkers and tobacco-induced cancer
SS Hecht
NATURE REVIEWS CANCER (2003)
'Dr Steinach coming to make old young!': sex glands, vasectomy and the quest for rejuvenation in the roaring twenties
C Sengoopta
ENDEAVOUR (2003)
An in vitro model of caloric restriction
R de Cabo et al.
EXPERIMENTAL GERONTOLOGY (2003)
Medical progress - Skin cancers after organ transplantation
S Euvrard et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Human telomerase and its regulation
YS Cong et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2002)
T cell subset patterns that predict resistance to spontaneous lymphoma, mammary adenocarcinoma, and fibrosarcoma in mice
RA Miller et al.
JOURNAL OF IMMUNOLOGY (2002)
Does p53 affect organismal aging?
LA Donehower
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
Age-dependency in hunting ability among the Ache of Eastern Paraguay
R Walker et al.
JOURNAL OF HUMAN EVOLUTION (2002)
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
WC Knowler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
p53 mutant mice that display early ageing-associated phenotypes
SD Tyner et al.
NATURE (2002)
Cellular senescence, cancer and aging: the telomere connection
J Campisi et al.
EXPERIMENTAL GERONTOLOGY (2001)
Genome maintenance mechanisms for preventing cancer
JHJ Hoeijmakers
NATURE (2001)
Calorie restriction and aging: A life-history analysis
DP Shanley et al.
EVOLUTION (2000)
Normal mouse and rat strains as models for age-related cataract and the effect of caloric restriction on its development
NS Wolf et al.
EXPERIMENTAL EYE RESEARCH (2000)
Height and risk of death among men and women: aetiological implications of associations with cardiorespiratory disease and cancer mortality
GD Smith et al.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH (2000)
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
G Barja et al.
FASEB JOURNAL (2000)