Journal
MATERIALS LETTERS
Volume 300, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.matlet.2021.130229
Keywords
Biomaterials; Nanofibrous textiles; Biocompatibility; Mechanical behavior; Biomedical application
Funding
- Shandong Science Foundation for Young Scholar [ZR2020QE090]
- Startup Grant of Qingdao University
- National Key Research and Development Program of China [2017YFB03098052]
- Shandong Provincial Key Research and Development Program, China [2018GGX108003]
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Development of ultra-strong and biocompatible nanofiber yarns for biomedical textile materials presents significant challenges. PLLA nanofiber yarns exhibit exciting mechanical properties and enhanced biocompatibility compared to commercial PLLA microfiber yarns, showing potential for future commercial applications in bio-textiles.
Developing ultra-strong and biocompatible nanofiber yarns for biomedical textile materials remains major challenges. Here, poly(L-lactic acid) (PLLA) nanofiber yarns (NYs) were fabricated by using a modified electrospinning apparatus with a integration function of yarn formation and thermal stretching. Due to the highlyaligned nanofibrous structure and obviously increased crystallinity, the as-prepared PLLA NYs exhibited exciting mechanical properties, which matched those of commercial PLLA microfiber yarns (MYs). The biological tests demonstrated that the braided fabrics made from PLLA NYs presented obviously enhanced biocompatibility than those made from PLLA MYs, by significantly promoting the survival, adhesion and proliferation of human adipose-derived mesenchymal stem cells (hADMSCs). We hope that these results provide new insights for the future development of nanofibrous bio-textiles for commercial applications.
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