Journal
MATERIALS LETTERS
Volume 304, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.matlet.2021.130574
Keywords
Screen-printed carbon electrode; Nonenzymatic; Conjugated bilirubin; Direct electro-oxidation
Funding
- Department of Biotechnology (DBT) , Government of India [102/IFD/SAN/2238/2016-17, 102/IFD/SAN/1555/2018-2019]
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The electrochemical oxidation of conjugated bilirubin was studied on an indigenously screen-printed carbon electrode (SPCE), which showed high selectivity and excellent response for conjugated bilirubin detection in urine samples. The SPCE demonstrated a dynamic detection range of 1-600 μM, making it a promising tool for conjugated bilirubin analysis.
Electrochemical oxidation of conjugated bilirubin has been studied on an indigenously screen-printed carbon electrode (SPCE). Microscopic, spectroscopic and electrochemical methods thoroughly characterized the electrode. The surface morphology of SPCE revealed graphite nanoparticles of size around 100 nm. The oxidation of bilirubin occurred on SPCE at lower anodic potential and was highly selective towards conjugated bilirubin in the presence of interfering molecules. The SPCE showed a dynamic detection range of 1-600 mu M. Conjugated bilirubin spiked urine samples were tested on SPCE and found excellent response.
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