Comparative analysis of synthesis, characterization, antimicrobial, antioxidant, and enzyme inhibition potential of roses petal based synthesized copper oxide nanoparticles

This study was aimed to compare physiochemical and biological properties of Rosa delicia (R.d), Rosa kardina (R. k), and Rosa foetida (R.f) petals based synthesis of copper oxide nanoparticles (CuO NPs). The nanoparticles were characterized by Fourier transform-infrared spectroscopy (FTIR), X-Ray diffraction (XRD), and Scanning electron microscopy (SEM). The XRD assured the pure monoclinic cubic structure of CuO NPs which were crystalline in nature. The sizes of the nanoparticles were 17.7 nm, 14.9 nm, and 26.3 nm for R. foetida, R. kardinal, and R. delicia, respectively. The binding of various functional groups to CuO NPs was verified by FTIR. The SEM images showed spherical-clustered, and crystalline nanoprism for R. f-CuO NPs, R.d-CuO NPs, and R.k-CuO NPs, respectively. The effectiveness of R.k-CuO NPs and plant extract against all the bacterial strains was found significant as compared to others. In comparison to other samples, R.k-CuO NPs had a greater antioxidant capacity (98.700.3 mu g AAE/mg) and reducing power potential (73.50.18 mu g AAE/mg). The highest DPPH scavenging potential was also observed by R.k-CuO NPs (60.9%). R.d-CuO NPs and extract exhibited the greatest urease inhibition, whereas R. f-CuO NPs and R.k-CuO NPs showed the greatest alpha-amylase and lipase inhibition, respectively. The significant peroxidase-like activity was depicted by R.k-CuO NPs and R. f-CuO NPs. This study concludes that Rosa species have significant potential to synthesize NPs that can be further explored for biomedical purposes. Differences in plant species also have an impact on the physicochemical and biological characteristics of NPs.

Automated summary

This study compares the physicochemical and biological properties of copper oxide nanoparticles synthesized from different species of roses. The results show that the size and structure of the nanoparticles are influenced by the plant species, and R.k-CuO NPs exhibit higher antioxidant and inhibitory potentials, suggesting potential biomedical applications.