Corrosion behviour of micro-arc oxidized titanium in NaCl solution with H2O2 and albumin

Investigations of in vivo corrosion behaviours of Ti-based orthopaedic implants are required for their clinical applications. In this work, C10H12CuN2Na2O8 (Na2Cu-EDTA) has been applied to fabricate a Cu-rich TiO2 ceramic layer on Ti substrate via micro-arc oxidation (MAO). The incorporation of Cu reduces the thickness and porosity of the resultant coating, which also affects its biological properties. With the addition of H2O2 and/or albumin in NaCl solution to simulate the peri-implant conditions, Cu-rich TiO2 ceramic layer displays a desirable chemical stability in simulated human environments whereas the synergistic effect of albumin and H2O2 dramatically affects the electrochemical responses of bare Ti and Cu-free TiO2 layer. Our present work illustrates the influence of in vivo chemical conditions on the corrosion properties of micro-arc oxidized titanium, which provides valuable guidance for its clinical application.

Automated summary

The Cu-rich TiO2 ceramic layer fabricated on a Ti substrate displays desirable chemical stability in simulated human environments, while the electrochemical responses of bare Ti and Cu-free TiO2 layer are significantly affected by the synergistic effect of albumin and H2O2. This study provides valuable guidance for the clinical application of micro-arc oxidized titanium under in vivo chemical conditions.