4.2 Article

Mouse Genome Informatics (MGI): latest news from MGD and GXD

Journal

MAMMALIAN GENOME
Volume 33, Issue 1, Pages 4-18

Publisher

SPRINGER
DOI: 10.1007/s00335-021-09921-0

Keywords

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Funding

  1. National Institutes of Health (NIH) [U24 HG000330, U24 HG10859, P41 HD062499]

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The Mouse Genome Informatics (MGI) database system combines expertly curated community data resources to facilitate the use of the mouse as an experimental model for understanding human health and disease genetics. MGI is the authoritative source for mouse gene information, maintains standard ontologies, and contributes to the development of gene and disease ontologies.
The Mouse Genome Informatics (MGI) database system combines multiple expertly curated community data resources into a shared knowledge management ecosystem united by common metadata annotation standards. MGI's mission is to facilitate the use of the mouse as an experimental model for understanding the genetic and genomic basis of human health and disease. MGI is the authoritative source for mouse gene, allele, and strain nomenclature and is the primary source of mouse phenotype annotations, functional annotations, developmental gene expression information, and annotations of mouse models with human diseases. MGI maintains mouse anatomy and phenotype ontologies and contributes to the development of the Gene Ontology and Disease Ontology and uses these ontologies as standard terminologies for annotation. The Mouse Genome Database (MGD) and the Gene Expression Database (GXD) are MGI's two major knowledgebases. Here, we highlight some of the recent changes and enhancements to MGD and GXD that have been implemented in response to changing needs of the biomedical research community and to improve the efficiency of expert curation. MGI can be accessed freely at .

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