Journal
LUNG
Volume 199, Issue 6, Pages 677-680Publisher
SPRINGER
DOI: 10.1007/s00408-021-00490-2
Keywords
Pulmonary fibrosis; Emphysema; Pulmonary hypertension; Idiopathic pulmonary fibrosis; Computed tomography (CT)
Categories
Funding
- NIH [1P20GM103652-01, 5R01HL130230]
- Advance Clinical and Translational Research (Advance-CTR) [U54GM115677]
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Our study found that PA/AA ratio > 1 is associated with decreased survival in individuals with pulmonary fibrosis, with or without emphysema. Additionally, the study describes markers of cardiac remodeling and the echocardiographic diagnosis of PH in this patient population.
Pulmonary hypertension (PH) is associated with decreased survival in patients with pulmonary fibrosis and combined pulmonary fibrosis and emphysema. Main pulmonary artery (PA) diameter and PA diameter/ascending aortic diameter (PA/AA) ratio, as measured on CT, have recently emerged as specific markers for PH. Our single-center retrospective study found that PA/AA ratio > 1 is associated with decreased survival in individuals with pulmonary fibrosis, with or without emphysema. Our study also describes markers of cardiac remodeling, and the echocardiographic diagnosis of PH in this patient population.
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