Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones

In the present study, a new magnetically recyclable nanocatalyst, Fe3O4@SiO2@(CH2)(3)-en-SO3H/H2SO4, was prepared through the immobilization of sulfonated ethylenediamine on the silica-coated magnetite nanoparticles. The catalyst was fully characterized by several physicochemical techniques, including FT-IR, FESEM, TEM, EDS, VSM, XRD and TGA. The resultant nanocatalyst was then utilized in the green synthesis of 2,3-dihydroquinazolin-4(1H)-ones via the cyclocondensationreaction of various aldehydes and ketones with anthranilamide in refluxed EtOH. Short reaction times, high product yields, environmentally friendly reaction conditions, simple operation and reusability of the catalyst are important features of the present procedure. The catalyst can magnetically be recycled and reused several times without notable loss in the activity.

Automated summary

In this study, a new magnetically recyclable nanocatalyst was prepared and successfully applied in green synthesis. The catalyst has multiple advantages and is suitable for environmentally friendly synthesis methods.