4.4 Article

Coating of Au@Ag on electrospun cellulose nanofibers for wound healing and antibacterial activity

Journal

KOREAN JOURNAL OF CHEMICAL ENGINEERING
Volume 39, Issue 8, Pages 2165-2171

Publisher

KOREAN INSTITUTE CHEMICAL ENGINEERS
DOI: 10.1007/s11814-021-1023-x

Keywords

Electrospinning; Cellulose Acetate; Nanoparticles; Wound Healing; Antibacterial Activity

Funding

  1. National Natural Science Foundation of China [21673201]
  2. top-notch Academic Programs Project of Jiangsu Higher Education Institutions of China (TAPP)
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions of China

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Electrospun cellulose acetate nanofibers were synthesized and decorated with Au@AgNPs to construct effective wound dressing material. The Au@AgNPs/cellulose exhibited excellent antimicrobial activity and showed promising results in wound healing experiment.
Electrospun cellulose acetate nanofibers were synthesized and deacetylated by alkaline hydrolysis. Au@AgNPs were synthesized and decorated on the surface of cellulose nanofibers. The Au@AgNPs was decorated by dipping method on the surface of cellulose nanofibers to construct effective wound dressing material. Au@NPs and Au@AgNPs/cellulose nanofibers were characterized by scanning electron microscope and transmission electron microscope. Moreover, antibacterial activity was assessed against E. coli and S. aureus finding Au@AgNPs/cellulose excellent antimicrobial material. Moreover the wound healing experiment was carried out by using Au@AgNPs/cellulose as a wound dressing material, and determining great results.

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