4.7 Review

Virus infection induced pulmonary fibrosis

Related references

Note: Only part of the references are listed.
Article Pathology

Fatal pulmonary fibrosis: a post-COVID-19 autopsy case

Hanna Ferlov Schwensen et al.

Summary: A Caucasian female in her 80s who died from severe pulmonary fibrosis after eliminating SARS-CoV-2 infection underwent autopsy, revealing widespread fibrosis in previously healthy lungs. The microscopic examination showed acute and organizing diffuse alveolar damage and fibrosis with honeycomb-like remodelling and bronchial metaplasia.

JOURNAL OF CLINICAL PATHOLOGY (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia

Xiaoyu Han et al.

Summary: The study found that over one-third of severe COVID-19 patients showed fibrotic-like changes in the lung at 6-month follow-up CT, which were associated with older age, acute respiratory distress syndrome, longer hospital stays, tachycardia, noninvasive mechanical ventilation, and higher initial chest CT score.

RADIOLOGY (2021)

Editorial Material Cell Biology

Autophagosome maturation stymied by SARS-CoV-2

Willa Wen-You Yim et al.

Summary: The study reveals that the SARS-CoV-2 protein ORF3a disrupts autophagy by interfering with the fusion between autophagosomes and lysosomes, through dysregulation of the HOPS complex.

DEVELOPMENTAL CELL (2021)

Article Critical Care Medicine

Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study

Anna Duckworth et al.

Summary: Using mendelian randomisation, this study found that shorter telomere length is associated with higher odds of IPF but not COPD, suggesting a potential contributory factor in IPF and differing mechanisms in COPD.

LANCET RESPIRATORY MEDICINE (2021)

Article Immunology

COVID-19 Lung Pathogenesis in SARS-CoV-2 Autopsy Cases

Silvana Valdebenito et al.

Summary: SARS-CoV-2-induced lung damage in COVID-19 patients is highly heterogeneous, manifesting as hemorrhage, immune infiltration, or a combination of both, leading to loss of alveolar wall integrity, lung tissue detachment, and fibrosis. Pathological analysis revealed a strong immune response in COVID-19 cases, with significant B cell infiltration and poor T cell infiltration, indicating a compromised immune cellular response in these patients.

FRONTIERS IN IMMUNOLOGY (2021)

Review Cell Biology

Role of interleukins in the pathogenesis of pulmonary fibrosis

Yi Xin She et al.

Summary: Interleukins play a crucial role in the development of pulmonary fibrosis, and targeting multiple interleukins with different functions or combining with other therapies may be a future direction. Timing of intervention and understanding the roles of interleukins at different stages are critical for therapeutic strategies.

CELL DEATH DISCOVERY (2021)

Article Microbiology

Clinical, Radiological and Functional Characteristics of Pulmonary Diseases among HTLV-1 Infected Patients without Prior Active Tuberculosis Infection

Rodrigo Cachay et al.

Summary: The study found that some HTLV-1-positive patients without a history of TB showed bronchiectasis and pulmonary fibrosis, with normal patterns in pulmonary function tests. However, the sample size was insufficient to draw conclusive results regarding the association between PVL, chest-CT scan findings, and spirometry results.

PATHOGENS (2021)

Article Respiratory System

Pulmonary fibrosis and its related factors in discharged patients with new corona virus pneumonia: a cohort study

Xiaohe Li et al.

Summary: Older age, higher BMI, severe/critical condition, fever, longer viral clearance time, pre-existing disease, and delayed hospitalization were identified as risk factors for developing persistent pulmonary fibrosis in COVID-19 patients. About one-third of fibrotic patients could reverse their condition after around 120 days from onset, and less than half of the patients had their lung function return to normal condition after three months from onset. An effective predictive model with an average AUC of 0.84 was established for early diagnosis of the persistence of pulmonary fibrosis in COVID-19 patients.

RESPIRATORY RESEARCH (2021)

Article Biochemistry & Molecular Biology

PAI-1 Regulation of TGF-β1-induced Alveolar Type II Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages

Tapasi Rana et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

Review Medical Laboratory Technology

Autophagy, an important therapeutic target for pulmonary fibrosis diseases

Hong Zhao et al.

CLINICA CHIMICA ACTA (2020)

Article Medicine, General & Internal

Clinical Characteristics of Coronavirus Disease 2019 in China

W. Guan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Letter Medicine, General & Internal

Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19

Huilan Zhang et al.

ANNALS OF INTERNAL MEDICINE (2020)

Editorial Material Respiratory System

Abnormal pulmonary function in COVID-19 patients at time of hospital discharge

Xiaoneng Mo et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

Article Medicine, Research & Experimental

Clinical and immunological features of severe and moderate coronavirus disease 2019

Guang Chen et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Multidisciplinary Sciences

Respiratory disease in rhesus macaques inoculated with SARS-CoV-2

Vincent J. Munster et al.

NATURE (2020)

Letter Infectious Diseases

Lung fibrosis: an undervalued finding in COVID-19 pathological series

Federica Grillo et al.

LANCET INFECTIOUS DISEASES (2020)

Review Immunology

Mechanisms of SARS-CoV-2 Transmission and Pathogenesis

Andrew G. Harrison et al.

TRENDS IN IMMUNOLOGY (2020)

Article Biochemistry & Molecular Biology

Transient Unfolding and Long-Range Interactions in Viral BCL2 M11 Enable Binding to the BECN1 BH3 Domain

Arvind Ramanathan et al.

BIOMOLECULES (2020)

Article Biochemistry & Molecular Biology

Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples

Ling Leng et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Article Medicine, General & Internal

HIV-1 Protein gp120 Induces Mouse Lung Fibroblast-to-Myofibroblast Transdifferentiation via CXCR4 Activation

Lucian T. Marts et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2019)

Review Microbiology

HTLV-1-Mediated Epigenetic Pathway to Adult T-Cell Leukemia-Lymphoma

Makoto Yamagishi et al.

FRONTIERS IN MICROBIOLOGY (2018)

Review Immunology

Type 2 immunity in tissue repair and fibrosis

Richard L. Gieseck et al.

NATURE REVIEWS IMMUNOLOGY (2018)

Article Medicine, General & Internal

Middle East Respiratory Syndrome

Yaseen M. Arabi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Pharmacology & Pharmacy

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis

Kelly L. Walton et al.

FRONTIERS IN PHARMACOLOGY (2017)

Article Medicine, Research & Experimental

Study of SMAD-Dependent Signal Pathway in the Development of Early Pulmonary Fibrosis in Mice Infected with Influenza A/H1N1 Virus

E. V. Shatskaya et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2017)

Article Immunology

Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort

Joseph K. Leader et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2016)

Article Microbiology

MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2

Man-Lung Yeung et al.

NATURE MICROBIOLOGY (2016)

Article Radiology, Nuclear Medicine & Medical Imaging

Persistence of lymphocytopenia with CT abnormalities among patients with critical H7N9 swine-origin influenza A virus infection

Cheng Chen et al.

JAPANESE JOURNAL OF RADIOLOGY (2015)

Article Radiology, Nuclear Medicine & Medical Imaging

Persistence of lymphocytopenia with CT abnormalities among patients with critical H7N9 swine-origin influenza A virus infection

Cheng Chen et al.

JAPANESE JOURNAL OF RADIOLOGY (2015)

Article Biochemistry & Molecular Biology

Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Axis Protects against Lung Fibrosis by Inhibiting the MAPK/NF-κB Pathway

Ying Meng et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)

Article Multidisciplinary Sciences

Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections

Zhen Zou et al.

NATURE COMMUNICATIONS (2014)

Article Microbiology

Infection with MERS-CoV Causes Lethal Pneumonia in the Common Marmoset

Darryl Falzarano et al.

PLOS PATHOGENS (2014)

Article Respiratory System

Interstitial Lung Disease in HIV

Sarah R. Doffman et al.

CLINICS IN CHEST MEDICINE (2013)

Article Medicine, General & Internal

Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection

Hai-Nv Gao et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Radiology, Nuclear Medicine & Medical Imaging

CT Scans of the Chest in Carriers of Human T-cell Lymphotropic Virus Type 1: Presence of Interstitial Pneumonia

Tsuneo Yamashiro et al.

ACADEMIC RADIOLOGY (2012)

Article Biochemistry & Molecular Biology

Influenza Induces Endoplasmic Reticulum Stress, Caspase-12-Dependent Apoptosis, and c-Jun N-Terminal Kinase-Mediated Transforming Growth Factor-β Release in Lung Epithelial Cells

Elle C. Roberson et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)

Article Radiology, Nuclear Medicine & Medical Imaging

Serial evaluation of high-resolution CT findings in patients with pneumonia in novel swine-origin influenza A (H1N1) virus infection

P. Li et al.

BRITISH JOURNAL OF RADIOLOGY (2012)

Article Radiology, Nuclear Medicine & Medical Imaging

Post-ARDS pulmonary fibrosis in patients with H1N1 pneumonia: role of follow-up CT

G. Mineo et al.

RADIOLOGIA MEDICA (2012)

Article Physiology

Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1-7/Mas axis

Bruce D. Uhal et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)

Article Critical Care Medicine

HIV Infection and Risk for Incident Pulmonary Diseases in the Combination Antiretroviral Therapy Era

Kristina Crothers et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Biochemistry & Molecular Biology

The Epstein-Barr Virus Latent Membrane Protein 1 and Transforming Growth Factor-β1 Synergistically Induce Epithelial-Mesenchymal Transition in Lung Epithelial Cells

Mark D. Sides et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)

Article Pathology

Inhibition of NF-κB Signaling Reduces Virus Load and Gammaherpesvirus-Induced Pulmonary Fibrosis

Laurie T. Krug et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Article Immunology

Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool

Pablo J. E. J. van de Berg et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Respiratory System

Pulmonary fibrosis induced by H5N1 viral infection in mice

Jian Qiao et al.

RESPIRATORY RESEARCH (2009)

Article Physiology

Alveolar epithelial cell injury with Epstein-Barr virus upregulates TGFβ1 expression

Andrea P. Malizia et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)

Review Respiratory System

Apoptosis in lung injury and fibrosis

F. Drakopanagiotakis et al.

EUROPEAN RESPIRATORY JOURNAL (2008)

Article Critical Care Medicine

Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-γ receptor-deficient mice

Ana L. Mora et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2007)

Review Pathology

Pathology and pathogenesis of severe acute respiratory syndrome

Jiang Gu et al.

AMERICAN JOURNAL OF PATHOLOGY (2007)

Article Critical Care Medicine

Acute respiratory distress syndrome induced by avian influenza A (H5N1) virus in mice

Tong Xu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Review Genetics & Heredity

Lessons from SARS: control of acute lung failure by the SARS receptor ACE2

Keiji Kuba et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2006)

Article Physiology

Lung infection with γ-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice

AL Mora et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)

Article Critical Care Medicine

Lung inflammation and fibrosis - An alveolar macrophage-centered perspective from the 1970s to 1980s

HY Reynolds

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

Article Pathology

Pulmonary pathology of severe acute respiratory syndrome in Toronto

DM Hwang et al.

MODERN PATHOLOGY (2005)

Article Radiology, Nuclear Medicine & Medical Imaging

Thin-section CT findings in 32 immunocompromised patients with cytomegalovirus pneumonia who do not have AIDS

T Franquet et al.

AMERICAN JOURNAL OF ROENTGENOLOGY (2003)

Article Critical Care Medicine

Occult herpes family viral infections are endemic in critically ill surgical patients

CH Cook et al.

CRITICAL CARE MEDICINE (2003)

Review Microbiology

SARS - Beginning to understand a new virus

K Stadler et al.

NATURE REVIEWS MICROBIOLOGY (2003)