Hypercoagulability of COVID-19 and Neurological Complications: A Review

The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination.

Automated summary

The COVID-19 pandemic has led to millions of deaths worldwide, with the potential for neurological complications caused by the virus. These complications may stem from the severity of systemic infection, direct viral invasion of the central nervous system, and possible immune mediated mechanisms.