Journal
JOURNAL OF SPINAL CORD MEDICINE
Volume -, Issue -, Pages -Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10790268.2021.1969503
Keywords
Traumatic spinal cord injury; Opioids; Pain management
Categories
Funding
- ICES - Ontario Ministry of Health and Long-Term Care (MOHLTC)
- Connaught New Investigator Award (University of Toronto)
- Craig H. Neilsen Foundation [PSR217, 441259]
- Canadian Institutes of Health Research Embedded Clinician Scientist Salary Award on Transitions in Care [368761]
- Canadian Institutes of Health Research New Investigator Award [361005]
- University of Toronto Department of Family & Community Medicine
- Peter Gilgan Centre for Women's Cancers at Women's College Hospital
- Canadian Cancer Society
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This study found that the majority of individuals eligible for Ontario's public drug program who experienced TSCI used opioids in the year following their injury. Being male, having chronic obstructive pulmonary disease, and using prescription opioids before injury were significantly associated with opioid use in the year after TSCI.
Objective To describe the proportion and identify predictors of community-dwelling individuals with traumatic spinal cord injury (TSCI) who were dispensed >= 1 publicly funded opioid in the year after injury using a retrospective cohort study. Setting Ontario, Canada. Participants, Interventions, Outcome Measures We used administrative data to identify predictors of receiving publicly funded prescription opioids during the year after injury for individuals who were injured between April 2004 and March 2015. Our outcome was modeled using robust Poisson multivariable regression and we reported adjusted relative risks (aRR) with 95% confidence intervals. Results In our retrospective cohort of 934 individuals with TSCI who were eligible for the provincial drug program, 510 (55%) received >= 1 prescription opioid in the year after their injury. Most individuals were male (71%) and the median age was 63 years (interquartile range: 42-72). Being male (aRR 1.15, 95% confidence interval [CI] 1.01-1.31), having chronic obstructive pulmonary disease (aRR 1.25, 95% CI 1.05-1.50), and using prescription opioids before injury (aRR 1.46, 95% CI 1.29-1.66) were significantly associated with receiving opioids in the year after TSCI. Short durations of hospital stay after injury were also identified as being a significant risk factor of outpatient opioid use (aRR = 1.28, 95% CI = 1.08-1.51) when compared to longer hospital stays. Conclusion This study presented evidence showing that most individuals eligible for Ontario's public drug program who experienced a TSCI used opioids in the year following their injury. Due to the paucity of research on this population and their potential for elevated risks of adverse events, it is important for additional studies to be conducted on opioid use in this population to understand short-term and long-term risks and benefits.
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