4.3 Review

Ethical considerations of maternal-fetal surgery

Journal

JOURNAL OF PERINATAL MEDICINE
Volume 50, Issue 5, Pages 519-527

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/jpm-2021-0476

Keywords

ethics; maternal-fetal surgery; prenatal intervention

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The practice of maternal-fetal surgery (MFS) has expanded from treating lethal fetal conditions to treating significantly disabling but not lethal fetal abnormalities. However, MFS still faces ethical issues, including patienthood of the fetus, balancing risks and benefits between mother and fetus, informed consent for experimental procedures, and determining the conditions suitable for MFS intervention.
The practice of maternal-fetal surgery (MFS) has expanded from lethal fetal conditions to conditions which are significantly disabling but not a lethal fetal abnormality. The inclusion of myelomeningocele within the scope of MFS in the 1990s sparked a renewed debate over the ethics of MFS. While demonstrating increasing efficacy and range of application, MFS continues to be ethically fraught due to the inherent tension between maternal and fetal interests. Ethical issues central to MFS include the patienthood of the fetus; the balance of risks and benefits between the woman and fetus; informed consent for experimental procedures; and determination of conditions that meet ethical qualifications for MFS intervention. These concerns are likely to persist and evolve as perinatal medicine continues to advance. Here we summarize the current state of MFS ethics, highlighting the major positions in the literature thus far as well as examine future directions. It is essential robust discussions of these important issues continue both to ensure ethical medical practice and to provide support to clinicians, pregnant women, and their families.

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