Journal
IMMUNITY
Volume 44, Issue 4, Pages 713-715Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2016.03.015
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- NIAID NIH HHS [R56 AI118719] Funding Source: Medline
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Generally, two signals are required to activate the NLRP3 inflammasome. In this issue of Immunity, Hornung and colleagues (2016) describe an alternative inflammasome activation pathway in human monocytes triggering activation of the NLRP3 inflammasome in response to a single stimulus.
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