Journal
IMMUNITY
Volume 45, Issue 2, Pages 227-228Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2016.08.006
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- Howard Hughes Medical Institute Funding Source: Medline
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The innate response to many pathogens involves type I interferon production that is initiated upon cytosolic detection of double-stranded DNA (dsDNA), but how dsDNA is detected is controversial. In this issue of Immunity, Gray et al. (2016) use genetics to bring some much-needed clarity to the field.
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